{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:04:39Z","timestamp":1780049079181,"version":"3.53.1"},"reference-count":18,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Soc. Bras. Med. Trop."],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>INTRODUCTION: Leptospirosis is an infectious disease caused by microorganisms of the genus Leptospira that affects several species of animals, including the human beings. The study described the confirmed cases of leptospirosis in Manaus, from 2000 to 2010. METHODS: A descriptive study based on secondary data analysis of Secretaria Municipal de Sa\u00fade (SEMSA), Sistema de Informa\u00e7\u00e3o de Agravos de Notifica\u00e7\u00e3o SINAN and Sistema de Informa\u00e7\u00e3o sobre Mortalidade (SIM) analyzing the variables: age group, gender, clinical aspects and geographic area and lethality. RESULTS: Were reported 665 cases of leptospirosis, 339 were confirmed and 35 (10.3%) died. The largest number of cases occurred in May (16.8%), March (13.3%) and April (11.4%), a period of intense rainfall. The city areas with the greatest occurrence of the disease were South (26.6%), West (23.5%) and East (19.7%), areas of the greatest precariousness socio-environment. The largest number of cases, including deaths, occurred in the age group from 14 to 44.9 years (74%), being that 291 (85.8%) were male and 48 (14.1%) females. The most frequent symptoms were fever, myalgia, headache and jaundice. In relation to the social conditions were identified low education, poor housing, absence of sanitation and low income. CONCLUSIONS: In Manaus, despite the implementation of the Social and Environmental Program of Igarap\u00e9s of Manaus (PROSAMIM), there are still areas that need a proper urbanization and improvements in socio-environmental conditions, reducing the level of exposure of the human beings that living in these locations.<\/jats:p>","DOI":"10.1590\/s0037-86822012000600011","type":"journal-article","created":{"date-parts":[[2013,1,5]],"date-time":"2013-01-05T12:48:20Z","timestamp":1357390100000},"page":"713-716","source":"Crossref","is-referenced-by-count":24,"title":["Cases distribution of leptospirosis in City of Manaus, State of Amazonas, Brazil, 2000-2010"],"prefix":"10.1590","volume":"45","author":[{"given":"Michele Silva de","family":"Jesus","sequence":"first","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciete Almeida","family":"Silva","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e1tia Maria da Silva","family":"Lima","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ormezinda Celeste Cristo","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1590\/S0037-86822001000400004","article-title":"Leptospirose humana no munic\u00edpio de Belo Horizonte, Minas Gerais, Brasil: uma abordagem geogr\u00e1fica","volume":"34","author":"Figueiredo CM","year":"2001","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.vetmic.2009.03.012","article-title":"Leptospira and leptospirosis","volume":"140","author":"Adler B","year":"2010","journal-title":"Vet Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0378-1135","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1097\/01.qco.0000178824.05715.2c","article-title":"Leptospirosis","volume":"18","author":"Mcbride AJA","year":"2005","journal-title":"Curr Opin Infect Dis"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1590\/S0034-89102010000200008","article-title":"An\u00e1lise espacial e sazonal da leptospirose no munic\u00edpio de S\u00e3o Paulo, SP, 1998 a 2006","volume":"44","author":"Soares TSM","year":"2010","journal-title":"Rev Saude Publica","ISSN":"https:\/\/id.crossref.org\/issn\/0034-8910","issn-type":"print"},{"key":"ref5","series-title":"Espa\u00e7o e doen\u00e7a: um olhar sobre o Amazonas","author":"Toledo LM.","year":"1998"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1590\/S0037-86822001000200004","article-title":"Estudo epidemiol\u00f3gico da leptospirose bovina e humana na Amaz\u00f4nia Oriental Brasileira","volume":"34","author":"Homem VSF","year":"2001","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref7","series-title":"Relat\u00f3rio urbano ambiental integrado","first-page":"188","author":"Velloso R","year":"2002"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1590\/S0037-86822007000500002","article-title":"Factors associated with Leptospira sp. infection in a large urban center in northeastern Brazil","volume":"40","author":"Dias J.P","year":"2007","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1590\/S0036-46652003000500002","article-title":"Human leptospirosis: a twenty-nine-year serological study in S\u00e3o Paulo, Brazil","volume":"5","author":"Romero EC","year":"2003","journal-title":"Rev Inst Med Trop S\u00e3o Paulo","ISSN":"https:\/\/id.crossref.org\/issn\/0036-4665","issn-type":"print"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1371\/journal.pmed.0030308","article-title":"Determining Risk for Severe Leptospirosis by Molecular Analysis of Environmental Surface Waters for Pathogenic Leptospira","volume":"3","author":"Ganoza CA","year":"2006","journal-title":"PLoS Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1590\/S0037-86822001000300006","article-title":"Formas graves de leptospirose: aspectos cl\u00ednicos, demogr\u00e1ficos e ambientais","volume":"34","author":"Costa E","year":"2001","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref12","series-title":"Relat\u00f3rio da Cheia 2009","year":"2009"},{"key":"ref13","series-title":"Diagn\u00f3stico de Leptospirose por PCR e caracteriza\u00e7\u00e3o de isolados de Leptospira spp. Por sequenciamento do 16S rDNA e an\u00e1lise de VNTR","author":"Jouglard SDD"},{"key":"ref14","first-page":"1","article-title":"A comparative study of leptospirosis and dengue in Thai children","volume":"1","author":"Librati DH","year":"2007","journal-title":"PLoS Negl Trop Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1590\/S0036-46652000000100008","article-title":"Systematic Reviews on Leptospirosis","volume":"42","author":"Guidugli F","year":"2000","journal-title":"Rev Inst Med Trop S\u00e3o Paulo","ISSN":"https:\/\/id.crossref.org\/issn\/0036-4665","issn-type":"print"},{"key":"ref16","first-page":"1","article-title":"Household transmission of leptospira infection in urban slum communities","volume":"2","author":"Maciel EAP","year":"2008","journal-title":"PLoS Negl Trop Dis"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1590\/S0034-89101994000100009","article-title":"Levantamento soroepidemiol\u00f3gico de Leptospirose em trabalhadores do servi\u00e7o de saneamento ambiental em localidade urbana da regi\u00e3o sul do Brasil","volume":"28","author":"Almeida LP","year":"1994","journal-title":"Rev Saude Publica","ISSN":"https:\/\/id.crossref.org\/issn\/0034-8910","issn-type":"print"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S0140-6736(99)80012-9","article-title":"Urban epidemic of severe leptospirosis in Brazil","volume":"354","author":"Ko AI","year":"1999","journal-title":"The Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0099-5355","issn-type":"print"}],"container-title":["Revista da Sociedade Brasileira de Medicina Tropical"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rsbmt\/v45n6\/11.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T11:15:51Z","timestamp":1495883751000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0037-86822012000600011&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S0037-86822012000600011"],"URL":"https:\/\/doi.org\/10.1590\/s0037-86822012000600011","relation":{},"ISSN":["0037-8682"],"issn-type":[{"value":"0037-8682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}