{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:47:11Z","timestamp":1784191631418,"version":"3.55.0"},"reference-count":12,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Soc. Bras. Med. Trop."],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>We report a severe case of diarrhea in a 62-year-old female HIV-negative patient from whom Giardia lamblia and Isospora belli were isolated. Because unusual and opportunistic infections should be considered as criteria for further analysis of immunological status, laboratory investigations led to a diagnosis of common variable immunodeficiency (CVID). This is the first reported case of isosporiasis in a patient with CVID and illustrates the importance of being aware of a possible link, particularly in relation to primary immunodeficiency.<\/jats:p>","DOI":"10.1590\/s0037-86822012000600023","type":"journal-article","created":{"date-parts":[[2013,1,5]],"date-time":"2013-01-05T12:48:34Z","timestamp":1357390114000},"page":"768-769","source":"Crossref","is-referenced-by-count":8,"title":["Common variable immunodeficiency and isosporiasis: first report case"],"prefix":"10.1590","volume":"45","author":[{"given":"Gisele Barbosa e","family":"Silva","sequence":"first","affiliation":[{"name":"Universidade Federal de Uberl\u00e2ndia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla Pereira","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Universidade Federal de Uberl\u00e2ndia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gesmar Rodrigues Silva","family":"Segundo","sequence":"additional","affiliation":[{"name":"Universidade Federal de Uberl\u00e2ndia; Universidade Federal de Uberl\u00e2ndia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","first-page":"219","article-title":"Infecci\u00f3n por Isospora belli en pacientes con infecci\u00f3n por VIH. 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