{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T21:14:49Z","timestamp":1772140489148,"version":"3.50.1"},"reference-count":15,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Hosp. Clin."],"published-print":{"date-parts":[[2002]]},"abstract":"<jats:p>A 7-year-old white boy was referred to us with a history of 3 attacks of hypogastric pain over the previous 2 years and persistently elevated serum amylase concentrations. At physical examination, he was well with no evidence of clinical abnormalities. His weight and height were normal. Laboratory diagnostic investigations were all normal except for the presence of Ascaris lumbricoides in the feces and persistently elevated serum amylase levels. Serum amylase determinations in the family members were normal in his father and maternal grandmother but elevated in his mother, sister, maternal aunt, and uncle, all of whom asymptomatic. Macroamylasemia was excluded in the child and in the mother. The finding of persistently elevated amylasemia in the child and in the other family members spanning 3 generations, and the exclusion of diseases that lead to hyperamilasemia are consistent with the diagnosis of familial hyperamylasemia. Until now, only 1 similar case has been reported. Familial hyperamylasemia must be considered in the differential diagnosis of hyperamylasemias in childhood.<\/jats:p>","DOI":"10.1590\/s0041-87812002000200006","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T13:22:17Z","timestamp":1114608137000},"page":"77-82","source":"Crossref","is-referenced-by-count":7,"title":["Familial hyperamylasemia"],"prefix":"10.1590","volume":"57","author":[{"given":"Yu Kar Ling","family":"Koda","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliana","family":"Vidolin","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1136\/gut.40.5.689","article-title":"Familial hyperamylasemia","volume":"40","author":"CUCKOW PM","year":"1997","journal-title":"Gut","ISSN":"https:\/\/id.crossref.org\/issn\/0017-5749","issn-type":"print"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1053\/gast.1996.v110.pm8964417","article-title":"Chronic nonpathological hyperamylasemia of pancreatic origin","volume":"110","author":"GULLO L","year":"1996","journal-title":"Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0016-5085","issn-type":"print"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"50","DOI":"10.7326\/0003-4819-106-1-50","article-title":"Hyperamylasemia in patients with eating disorders","volume":"106","author":"HUMPHRIES LL","year":"1987","journal-title":"Ann Intern Med","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"issue":"5","key":"ref4","first-page":"480","article-title":"Elevated serum amylase activity in the absence of clinical pancreatic or salivary gland disease; 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