{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:06:27Z","timestamp":1773277587014,"version":"3.50.1"},"reference-count":22,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. esc. enferm. USP"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p>Ophthalmoscopy performed for the early diagnosis of retinopathy of prematurity (ROP) is painful for preterm infants, thus necessitating interventions for minimizing pain. The present study aimed to establish the effectiveness of human milk, compared with sucrose, for pain relief in premature infants subjected to ophthalmoscopy for the early diagnosis of ROP. This investigation was a pilot, quasi-experimental study conducted with 14 premature infants admitted to the neonatal intensive care unit (NICU) of a university hospital. Comparison between the groups did not yield a statistically significant difference relative to the crying time, salivary cortisol, or heart rate (HR). Human milk appears to be as effective as sucrose in relieving acute pain associated with ophthalmoscopy. The study\u2019s limitations included its small sample size and lack of randomization. Experimental investigations with greater sample power should be performed to reinforce the evidence found in the present study.<\/jats:p>","DOI":"10.1590\/s0080-623420130000500005","type":"journal-article","created":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T18:26:12Z","timestamp":1387218372000},"page":"1039-1045","source":"Crossref","is-referenced-by-count":15,"title":["Human milk for neonatal pain relief during ophthalmoscopy"],"prefix":"10.1590","volume":"47","author":[{"given":"Laiane Medeiros","family":"Ribeiro","sequence":"first","affiliation":[{"name":"University of Brasilia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thaila Correa","family":"Castral","sequence":"additional","affiliation":[{"name":"University of Goias,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liciane Langona","family":"Montanholi","sequence":"additional","affiliation":[{"name":"University of Sao Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Firmino","family":"Dare","sequence":"additional","affiliation":[{"name":"University of Sao Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Carolina de Araujo","family":"Silva","sequence":"additional","affiliation":[{"name":"University of Sao Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonir Roberto Rauber","family":"Antonini","sequence":"additional","affiliation":[{"name":"University of Sao Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen Gracinda Silvan","family":"Scochi","sequence":"additional","affiliation":[{"name":"University of Sao Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"5","key":"ref1","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1590\/S0004-27492007000500028","article-title":"Proposta de diretrizes brasileiras do exame e tratamento de retinopatia da prematuridade (ROP).","volume":"70","year":"2007","journal-title":"ArqBras Oftalmol."},{"issue":"5","key":"ref2","doi-asserted-by":"crossref","first-page":"e518","DOI":"10.1542\/peds.2004-1180","article-title":"Characteristics of infants with severe retinopathy of prematurity in countries with low, moderate, and high levels of development: implications for screening programs.","volume":"115","year":"2005","journal-title":"Pediatrics."},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1001\/archpedi.155.2.173","article-title":"International Evidence-Based Group for Neonatal Pain. 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