{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:13:12Z","timestamp":1784297592694,"version":"3.55.0"},"reference-count":42,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Col. Bras. Cir."],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:p>OBJETIVO: Analisar os resultados obtidos no Servi\u00e7o de Cirurgia Geral do Hospital Universit\u00e1rio Cajuru - PUCPR, com o tratamento da gangrena de Fournier. M\u00c9TODOS: Foram revisados os prontu\u00e1rios de 40 pacientes com diagn\u00f3stico de Gangrena de Fournier internados no hospital universit\u00e1rio Cajuru de Novembro de 1999 a Abril de 2006, analisando-se as vari\u00e1veis: sexo, idade, fatores predisponentes, etiologia, localiza\u00e7\u00e3o da les\u00e3o, exames laboratoriais, procedimentos cir\u00fargicos realizados, antibioticoterapia e utiliza\u00e7\u00e3o de c\u00e2mara hiperb\u00e1rica. RESULTADOS: A etiologia mais comum foi de origem anorretal. O agente etiol\u00f3gico mais prevalente foi a E. coli. O fator predisponente predominantes foi a diabetes mellitus, A maioria dos pacientes eram do sexo masculino. A localiza\u00e7\u00e3o e extens\u00e3o da les\u00e3o mais freq\u00fcente foi a perineal. Todos foram submetidos \u00e0 desbridamento cir\u00fargico, 17 \u00e0 colostomia e dois \u00e0 cistostomia. Todos os pacientes utilizaram antibi\u00f3tico, sendo os mais usados: metronidazol e gentamicina. Vinte e seis pacientes submeteram-se \u00e0 terapia hiperb\u00e1rica. A mortalidade global foi de 20%. CONCLUS\u00c3O: A S\u00edndrome de Fournier, apesar de todos os avan\u00e7os terap\u00eauticos atuais, continua apresentando altos \u00edndices de mortalidade. O reconhecimento precoce da infec\u00e7\u00e3o associado a tratamento agressivo e invasivo s\u00e3o medidas essenciais para se tentar diminuir esses \u00edndices progn\u00f3sticos.<\/jats:p>","DOI":"10.1590\/s0100-69912010000600010","type":"journal-article","created":{"date-parts":[[2017,2,4]],"date-time":"2017-02-04T08:28:18Z","timestamp":1486196898000},"page":"435-441","source":"Crossref","is-referenced-by-count":43,"title":["Manejo da gangrena de Fournier: experi\u00eancia de um hospital universit\u00e1rio de Curitiba"],"prefix":"10.1590","volume":"37","author":[{"given":"Adriano Antonio","family":"Mehl","sequence":"first","affiliation":[{"name":"PUCPR, BR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorivam Celso","family":"Nogueira Filho","sequence":"additional","affiliation":[{"name":"PUCPR, BR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Marques","family":"Mantovani","sequence":"additional","affiliation":[{"name":"PUCPR, 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