{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T05:41:07Z","timestamp":1737006067243,"version":"3.33.0"},"reference-count":22,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cad. Sa\u00fade P\u00fablica"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p>Foi estudado o crit\u00e9rio de confirma\u00e7\u00e3o etiol\u00f3gica: cultura, cl\u00ednico, teste do L\u00e1tex e contraimunoeletroforese, exame bacteriosc\u00f3pico e cl\u00ednico\/epidemiol\u00f3gico dos 568 casos notificados de doen\u00e7a meningoc\u00f3cica na Regi\u00e3o Metropolitana de Campinas, S\u00e3o Paulo, Brasil, de 1993 a 2002. Foram analisadas as vari\u00e1veis: forma cl\u00ednica, idade, sexo, local de moradia e interna\u00e7\u00e3o, \u00e9poca do ano de ocorr\u00eancia, letalidade e sorogrupo da Neisseria meningitidis. Confirmaram-se, pela cultura, 68,7% dos casos. A letalidade foi diferente de acordo com o crit\u00e9rio de confirma\u00e7\u00e3o da doen\u00e7a. As formas cl\u00ednicas: meningite sem meningococcemia (OR = 2,87; IC: 1,89-4,38) e a meningococcemia sem meningite (OR = 0,26; IC: 0,17-0,45) mostraram-se associadas com o crit\u00e9rio cultura. Maior aten\u00e7\u00e3o \u00e0 confirma\u00e7\u00e3o diagn\u00f3stica deve ser dada aos casos mais severos. A utiliza\u00e7\u00e3o do teste da rea\u00e7\u00e3o em cadeia de polimerase pode ser \u00fatil para aumentar a capacidade da confirma\u00e7\u00e3o etiol\u00f3gica da doen\u00e7a meningoc\u00f3cica em casos de culturas negativas.<\/jats:p>","DOI":"10.1590\/s0102-311x2004000600010","type":"journal-article","created":{"date-parts":[[2007,5,4]],"date-time":"2007-05-04T20:58:07Z","timestamp":1178312287000},"page":"1531-1537","source":"Crossref","is-referenced-by-count":1,"title":["Crit\u00e9rio diagn\u00f3stico da doen\u00e7a meningoc\u00f3cica na Regi\u00e3o Metropolitana de Campinas, S\u00e3o Paulo, Brasil"],"prefix":"10.1590","volume":"20","author":[{"given":"Maria Rita","family":"Donalisio","sequence":"first","affiliation":[{"name":"Universidade Estadual de Campinas, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilu Mendes Moscardini","family":"Rocha","sequence":"additional","affiliation":[{"name":"Instituto Adolfo Lutz, 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