{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T07:56:31Z","timestamp":1693382191524},"reference-count":36,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ABCD, arq. bras. cir. dig."],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p>RACIONAL: A gastrorrafia isolada ou associada ao uso de adesivos biol\u00f3gicos constituiu ao longo da hist\u00f3ria da cirurgia a forma usual de promover a cicatriza\u00e7\u00e3o nas les\u00f5es g\u00e1stricas e o uso de fitoter\u00e1picos tem sido cada vez mais empregado. OBJETIVO: Avaliar a cicatriza\u00e7\u00e3o de ferida provocada no est\u00f4mago de ratos com uso do extrato hidroalco\u00f3lico de Schinus terebinthifolius Raddi. M\u00c9TODOS: Foram utilizados 60 ratos, adultos, machos, distribu\u00eddos em dois grupos: grupo aroeira e grupo controle, os quais foram subdivididos em tr\u00eas subgrupos de cinco animais conforme o momento das mortes dos animais (7, 14 e 21 dias). Todos os animais foram submetidos ao mesmo procedimento cir\u00fargico (les\u00e3o e rafia do est\u00f4mago) diferindo apenas que os animais do grupo aroeira receberam dose di\u00e1ria de 100 mg\/kg do extrato hidroalco\u00f3lico via gavagem enquanto o grupo controle recebeu solu\u00e7\u00e3o salina isot\u00f4nica. Os par\u00e2metros avaliados foram: altera\u00e7\u00f5es macrosc\u00f3picas e microsc\u00f3picas, teste de resist\u00eancia \u00e0 insufla\u00e7\u00e3o de ar atmosf\u00e9rico e teste pela for\u00e7a de tra\u00e7\u00e3o. RESULTADOS: Todos os animais demonstraram boa cicatriza\u00e7\u00e3o da parede abdominal e das gastrorrafias, sem infec\u00e7\u00e3o e deisc\u00eancia. Ambos os grupos apresentaram ader\u00eancias \u00e0 superf\u00edcie das gastrorrafias com \u00f3rg\u00e3os vizinhos. O teste de resist\u00eancia por insufla\u00e7\u00e3o de ar atmosf\u00e9rico e for\u00e7a de tra\u00e7\u00e3o mostraram maiores m\u00e9dias de press\u00e3o no 7\u00ba dia e de for\u00e7a de ruptura nos per\u00edodos estudados para o grupo aroeira. A intensidade da inflama\u00e7\u00e3o cr\u00f4nica revelou diferen\u00e7a estatisticamente significante nas vari\u00e1veis prolifera\u00e7\u00e3o fobrobr\u00e1stica e colageniza\u00e7\u00e3o. CONCLUS\u00c3O: O uso do extrato hidroalco\u00f3lico de Schinus terebinthifolius Raddi acelerou a cicatriza\u00e7\u00e3o do est\u00f4mago de ratos.<\/jats:p>","DOI":"10.1590\/s0102-67202012000300002","type":"journal-article","created":{"date-parts":[[2013,2,9]],"date-time":"2013-02-09T11:36:40Z","timestamp":1360409800000},"page":"140-146","source":"Crossref","is-referenced-by-count":11,"title":["Schinus terebinthifolius raddi (anacardiaceae) no processo de cicatriza\u00e7\u00e3o de gastrorrafias em ratos"],"prefix":"10.1590","volume":"25","author":[{"given":"Orlando Jos\u00e9 Dos","family":"Santos","sequence":"first","affiliation":[{"name":"Universidade Federal do Maranh\u00e3o, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan Kardec Duailibe","family":"Barros-Filho","sequence":"additional","affiliation":[{"name":"Universidade Federal do Maranh\u00e3o, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osvaldo","family":"Malafaia","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica do Paran\u00e1, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jurandir Marcondes","family":"Ribas-Filho","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica do Paran\u00e1, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rayan Haquim Pinheiro","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal da Para\u00edba, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rennan Abud Pinheiro","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal do Maranh\u00e3o, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1590\/S0100-72032003000200004","article-title":"Tratamento de vaginose bacteriana com gel vaginal de Aroeira (Schinus terebinthifolius Raddi): ensaio cl\u00ednico randomizado","volume":"25","author":"Amorim MMR","year":"2003","journal-title":"Revista Brasileira de Ginecologia e Obstetr\u00edcia","ISSN":"http:\/\/id.crossref.org\/issn\/0100-7203","issn-type":"print"},{"key":"ref2","first-page":"9","volume":"24","author":"Bornemisza G","year":"1983","journal-title":"Acta Chirurgica Hungarica","ISSN":"http:\/\/id.crossref.org\/issn\/0231-4614","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1590\/S0102-86502006000800004","article-title":"Avalia\u00e7\u00e3o do extrato hidroalco\u00f3lico de Aroeira (Schinus terebinthifolius Raddi) no processo de cicatriza\u00e7\u00e3o de feridas em pele de ratos","volume":"21","author":"Branco Neto MLC","year":"2006","journal-title":"Acta Cir\u00fargica Brasileira","ISSN":"http:\/\/id.crossref.org\/issn\/0102-8650","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1590\/S0102-695X2010000200001","article-title":"Antiulcer effect of the pepper trees Schinus terebinthifolius Raddi (aroeira da praia) and Myracrodruon urundeuva Allem\u00e3o, Anacardiaceae (aroeira-do-sert\u00e3o)","volume":"20","author":"Carlini EA","year":"2010","journal-title":"Brazilian Journal of Pharmacognosy"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/em.10183","article-title":"Evaluation of mutagenic activity in an extract of pepper tree stem bark (Schinus terebinthifolius Raddi)","volume":"42","author":"Carvalho MCRD","year":"2003","journal-title":"Environmental and Molecular Mutagenesis","ISSN":"http:\/\/id.crossref.org\/issn\/0893-6692","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1590\/S0100-40421998000100015","article-title":"Estrat\u00e9gias para a obten\u00e7\u00e3o de compostos farmacologicamente ativos a partir de plantas medicinais: conceitos sobre modifica\u00e7\u00e3o estrutural para otimiza\u00e7\u00e3o da atividade","volume":"21","author":"Cechinel Filho V","year":"1998","journal-title":"Qu\u00edmica Nova","ISSN":"http:\/\/id.crossref.org\/issn\/0100-4042","issn-type":"print"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1590\/S0100-40422007000300018","article-title":"Constituintes fen\u00f3licos polares de Schinus terebinthifolius Raddi (anacardiaceae)","volume":"30","author":"Ceruks M","year":"2007","journal-title":"Qu\u00edmica Nova","ISSN":"http:\/\/id.crossref.org\/issn\/0100-4042","issn-type":"print"},{"key":"ref8","first-page":"17","article-title":"Cicatriza\u00e7\u00e3o das feridas - Revis\u00e3o da Literatura","volume":"84","author":"Corsi RCC","year":"1994","journal-title":"Rev. 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