{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:20:51Z","timestamp":1772119251029,"version":"3.50.1"},"reference-count":10,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ABCD, arq. bras. cir. dig."],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:p>Background: Through rhythmic variations, the diaphragm influence lower esophageal sphincter (LES) pressure acting as an external sphincter. LES pressure recording is characterized by increased pressure in inspiration due to contraction of the diaphragmatic crura that involves the sphincter. Aim: To describe a method of measuring LES pressure during standardized inspiratory maneuvers with increasing loads. Methods: The study population comprised of eight healthy female volunteers (average age of 31.5 years). An esophageal high-resolution manometry and impedance system was used for measuring the LES pressure during 3-second inspiratory efforts under 12, 24 and 48 cm H2O loads (Threshold maneuvers). Results: There was a significant difference between the average maximum LES pressure and the average maximum basal LES pressure during the first (76.19\u00b117.92 difference, p=0.0008), second (86.92\u00b119.01 difference, p=0.0004), and third seconds of the maneuver (90.86\u00b117.93 difference, p=0.0002), with 12, 24 and 48 cmH2O loads. Conclusion: This maneuver is a standardization of the inspiratory LES pressure and may better differentiate patients with reflux disease from healthy individuals, and may also be useful for monitoring the treatment of these patients through inspiratory muscle training.<\/jats:p>","DOI":"10.1590\/s0102-67202015000300007","type":"journal-article","created":{"date-parts":[[2015,10,29]],"date-time":"2015-10-29T03:03:20Z","timestamp":1446087800000},"page":"174-177","source":"Crossref","is-referenced-by-count":8,"title":["LOWER ESOPHAGEAL SPHINCTER PRESSURE MEASUREMENT UNDER STANDARDIZED INSPIRATORY MANEUVEURS"],"prefix":"10.1590","volume":"28","author":[{"given":"Jeany Borges e Silva","family":"RIBEIRO","sequence":"first","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther Cristina Arruda Oliveira","family":"DI\u00d3GENES","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia Carvalho","family":"BEZERRA","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanila Aguiar Andrade","family":"COUTINHO","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00edcera Ge\u00f3rgia F\u00e9lix de","family":"ALMEIDA","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel \u00c2ngelo Nobre e","family":"SOUZA","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"T\u00e9cnicas para desmame do ventilador mec\u00e2nico","author":"Azeredo CAC","year":"2002"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1053\/j.gastro.2004.11.008","article-title":"Thecnical review on the clinical use of esophageal manometry","volume":"128","year":"2005","journal-title":"Gastroenterology"},{"key":"ref3","article-title":"Efeito do treinamento muscular respirat\u00f3rio por meio do manovacu\u00f4metro e do Threshold Pep em pacientes hemipar\u00e9ticos hospitalizados","author":"Fernades FE","year":"2007","journal-title":"CLAIB 2007"},{"key":"ref4","first-page":"15","article-title":"Esophageal Manometry","volume":"2","author":"Gomes J.","year":"2011","journal-title":"GI Motility Testing: A Laboratory and Office Handbook"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1152\/ajpgi.1990.258.4.G624","article-title":"Human lower esophageal sphincter pressure response to increased intra-abdominal pressure","volume":"258","author":"Mittal RK","year":"1990","journal-title":"Am. 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Liver Physiol"},{"issue":"9","key":"ref6","doi-asserted-by":"crossref","first-page":"e591","DOI":"10.1111\/nmo.12168","article-title":"Esophago-gastric junction pressure morphology: comparison between a station pull-through and real-time 3D-HRM representation","volume":"25","author":"Nicod\u00e8me F","year":"2013","journal-title":"Neurogastroenterol Motil"},{"issue":"2","key":"ref7","first-page":"59","article-title":"Avalia\u00e7\u00e3o funcional do esf\u00edncter esof\u00e1gico inferior por manometria esof\u00e1gica","volume":"19","author":"Luis Novais","year":"2012","journal-title":"J Port Gastrenterol"},{"issue":"11","key":"ref8","doi-asserted-by":"crossref","first-page":"G862","DOI":"10.1152\/ajpgi.00054.2013","article-title":"Inspiratory muscle training improves antireflux barrier in GERD patients","volume":"305","author":"Nobre e Souza M\u00c2","year":"2013","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"7","key":"ref9","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.3748\/wjg.v21.i7.2067","article-title":"Increased inspiratory esophagogastric junction pressure in systemic sclerosis: An add-on to antireflux barrier","volume":"21","author":"Nobre e Souza M\u00c2","year":"2015","journal-title":"World J Gastroenterol, 21"},{"key":"ref10","series-title":"Treinamento muscular inspirat\u00f3rio em pacientes sob desmame da ventila\u00e7\u00e3o mec\u00e2ncia","author":"Pires VA","year":"1999"}],"container-title":["ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S\u00e3o Paulo)"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abcd\/v28n3\/0102-6720-abcd-28-03-00174.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T02:43:56Z","timestamp":1567305836000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-67202015000300174&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0102-67202015000300174"],"URL":"https:\/\/doi.org\/10.1590\/s0102-67202015000300007","relation":{},"ISSN":["0102-6720"],"issn-type":[{"value":"0102-6720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9]]}}}