{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T19:54:22Z","timestamp":1760471662815},"reference-count":33,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:p>OBJETIVO: O estudo foi desenvolvido para avaliar os efeitos do autotransplante espl\u00eanico na prote\u00e7\u00e3o contra sepse abdominal em ratos Wistar jovens e adultos. M\u00c9TODOS: Foram utilizados 54 ratos Wistar jovens e adultos (90 e 180 dias respectivamente) sendo distribu\u00eddos em 3 grupos: Grupo Sham, onde os animais eram submetidos a laparotomia com manipula\u00e7\u00e3o de al\u00e7as apenas (n=6 animais jovens adultos), Grupo Esplenectomia, no qual os animais eram submetidos a esplenectomia total (n=10 animais jovens e adultos) e Grupo Auto-implante, onde os animais eram submetidos a esplenectomia total e um ter\u00e7o do ba\u00e7o era implantado em uma bolsa no retroperit\u00f4nio (n=10 animais jovens e adultos). Ap\u00f3s tr\u00eas meses os animais eram submetidos a nova laparotomia com ligadura e perfura\u00e7\u00e3o do ceco para estimular a sepse abdominal e acompanhados at\u00e9 o momento do \u00f3bito para estabelecimento de uma curva de mortalidade. RESULTADOS: Houve recupera\u00e7\u00e3o do ba\u00e7o implantado em todos os animais. N\u00e3o houve diferen\u00e7a significativa entre o tempo de \u00f3bito entre os grupos. Os animais jovens aparentemente tiveram uma melhor resposta embora n\u00e3o estatisticamente significativa. CONCLUS\u00c3O: Este estudo demonstrou que o auto-implante de ba\u00e7o no retroperit\u00f4nio n\u00e3o prov\u00ea prote\u00e7\u00e3o efetiva contra sepse abdominal em compara\u00e7\u00e3o aos ratos esplenectomizados.<\/jats:p>","DOI":"10.1590\/s0102-86502005000600014","type":"journal-article","created":{"date-parts":[[2006,1,9]],"date-time":"2006-01-09T17:26:48Z","timestamp":1136827608000},"page":"473-477","source":"Crossref","is-referenced-by-count":1,"title":["Resist\u00eancia de ratos \u00e0 peritonite fecal quando submetidos a esplenectomia e auto-implante do ba\u00e7o no retroperit\u00f4nio"],"prefix":"10.1590","volume":"20","author":[{"given":"Darlan de Medeiros","family":"Kestering","sequence":"first","affiliation":[{"name":"UNISUL; UFSC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando Jos\u00e9","family":"d'Acampora","sequence":"additional","affiliation":[{"name":"UFSC; UNIFESP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9bora 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