{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:16:47Z","timestamp":1792801007596,"version":"4.5.0"},"reference-count":17,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:p>PURPOSE: To evaluate the effects of the oxidative stress in an experimental model of torsion\/detorsion of the spermatic cord and the legitimacy of this model for oxidative stress studies. METHODS: Forty-eight male Wistar rats were randomized in two groups (n=24): G-1 (Sham) and G-2 (Ischemia\/Reperfusion). All rats received intraperitoneal saline injections (2.0 ml), at 21, 9, and 1 h before right spermatic cord torsion or first sham operation. Detorsion or second sham operation was carried out 3 h later followed by testis and blood samples collection (T-0). Additional samples were collected at 1-3-6 h time-points for assessment of testis malonaldehyde, glutathione, and plasma total antioxidant power (TAP). RESULTS: Spermatic cord torsion\/detorsion induced a significant increase in testicular malonaldehyde contents and a significant decrease in glutathione concentrations in ischemic rats compared with sham animals. Additional increase in malonaldehyde levels occurred during reperfusion in G-2 rats. TAP was similar in both groups denoting absence of systemic effects in this study. CONCLUSION: Torsion\/detorsion of the spermatic cord for 3 h induces significant lipid peroxidation and reduction in glutathione content of the testis and is, therefore, a valid model for studying the oxidative stress effects of the ischemia\/reperfusion injury in young rat testis.<\/jats:p>","DOI":"10.1590\/s0102-86502007000100005","type":"journal-article","created":{"date-parts":[[2007,3,26]],"date-time":"2007-03-26T19:05:00Z","timestamp":1174935900000},"page":"30-33","source":"Crossref","is-referenced-by-count":19,"title":["Oxidative stress induced by torsion of the spermatic cord in young rats"],"prefix":"10.1590","volume":"22","author":[{"given":"Sergio Botelho","family":"Guimar\u00e3es","sequence":"first","affiliation":[{"name":"UFC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan Arruda","family":"Arag\u00e3o","sequence":"additional","affiliation":[{"name":"UFC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jefferson Menezes 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