{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T05:08:26Z","timestamp":1649135306425},"reference-count":34,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:p>PURPOSE: The usefulness of body movements that occur during sleep when assessing perinatal asphyxia and predicting its long-term consequences is contradictory. This study investigated whether neonatal rats manifest these movements in compensatory rebound after asphyxia, and if these alterations play an important role in its pathogenesis. METHODS: Eight neonatal rats (aged 6-48h) were implanted with small EMG and EKG electrodes and sleep movements were recorded over a 30-minute control period. Recordings were continued during asphyxia caused by the enclosure of the animal in a polyvinyl sheet for 60 minutes, followed by a 30-minute recovery period. RESULTS: Heart rate was lowered to bradycardic level during asphyxia causing behavioral agitation and increased waking time during the initial phase (30 minutes). Sleep-related movements were also significantly reduced from 12.5 \u00b1 0.5 (median \u00b1 SE\/2min) to 9.0 \u00b1 0.44 in the final half of the period (Anova, p&lt;0.05). Movement frequency increased in the recovery period to 15.0 \u00b1 0.49 (Anova, p&lt;0.05). CONCLUSION: These data show that newborn rats present compensatory rebound of body movements during sleep which may help in the diagnosis of asphyxia and other problems related to sleep parameters.<\/jats:p>","DOI":"10.1590\/s0102-86502008000300007","type":"journal-article","created":{"date-parts":[[2008,6,12]],"date-time":"2008-06-12T04:12:52Z","timestamp":1213243972000},"page":"253-257","source":"Crossref","is-referenced-by-count":0,"title":["Compensatory rebound of body movements during sleep, after asphyxia in neonatal rats"],"prefix":"10.1590","volume":"23","author":[{"given":"Olivia Adayr Xavier","family":"Suarez","sequence":"first","affiliation":[{"name":"UNESP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsumasa","family":"Hoshino","sequence":"additional","affiliation":[{"name":"UNESP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"7","key":"ref1","first-page":"210","article-title":"Risk factors 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