{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:29:46Z","timestamp":1777487386480,"version":"3.51.4"},"reference-count":13,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:p>Purpose: Analyze the influence of low-intensity laser therapy in the sciatic nerve regeneration of rats submitted to controlled crush through histological analysis. Methods: Were used 20 Wistar rats, to analyze the influence of low-intensity laser therapy in the sciatic nerve regeneration, where the injury of the type axonotmesis was induced by a haemostatic clamp Crile (2nd level of the rack). The animals were randomly distributed in 2 groups. Control group (CG n = 10) and Laser group (LG n = 10). These were subdivided in 2 subgroups each, according to the euthanasia period: (CG14 _ n = 5 and CG21 _ n = 5) and (LG14 _ n = 5 and LG21 _ n = 5). At the end of treatment, the samples were removed and prepared for histological analysis, where were analyzed and quantified the following findings: Schwann cells, myelinic axons with large diameter and neurons. Results: In the groups submitted to low-intensity laser therapy, were observed an increase in the number of all analyzed aspects with significance level. Conclusion: The irradiation with low intensity laser (904nm) influenced positively the regeneration of the sciatic nerve in Wistar rats after being injured by crush (axonotmesis), becoming the nerve recovery more rapid and efficient.<\/jats:p>","DOI":"10.1590\/s0102-86502011000100004","type":"journal-article","created":{"date-parts":[[2011,1,27]],"date-time":"2011-01-27T08:25:47Z","timestamp":1296116747000},"page":"12-18","source":"Crossref","is-referenced-by-count":44,"title":["Histological analysis of low-intensity laser therapy effects in peripheral nerve regeneration in Wistar rats"],"prefix":"10.1590","volume":"26","author":[{"given":"Cibele Nazar\u00e9 da Silva","family":"C\u00e2mara","sequence":"first","affiliation":[{"name":"UNAMA,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus Vinicius Henriques","family":"Brito","sequence":"additional","affiliation":[{"name":"UEPA,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edvaldo Lima","family":"Silveira","sequence":"additional","affiliation":[{"name":"UEPA,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego S\u00e1 Guimar\u00e3es da","family":"Silva","sequence":"additional","affiliation":[{"name":"UEPA,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian Roberta Ferreira","family":"Sim\u00f5es","sequence":"additional","affiliation":[{"name":"UEPA,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto Waldesmand Farias","family":"Pontes","sequence":"additional","affiliation":[{"name":"UEPA,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1590\/S1413-35552006000100015","article-title":"Os efeitos do ultra-som terap\u00eautico nas les\u00f5es por esmagamento do nervo ci\u00e1tico de ratos: an\u00e1lise funcional da marcha","volume":"10","author":"Monte-Raso VV","year":"2006","journal-title":"Rev Bras Fisioter."},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1590\/S1413-78522006000400005","article-title":"Les\u00e3o por esmagamento do nervo isqui\u00e1tico de ratos: estudo da vasculariza\u00e7\u00e3o","volume":"14","author":"Pachioni CAS","year":"2006","journal-title":"Acta Ortop Bras"},{"issue":"51","key":"ref3","doi-asserted-by":"crossref","first-page":"20505_10","DOI":"10.1073\/pnas.0811201106","article-title":"Etifoxine improves peripheral nerve regeneration and functional recovery","volume":"105","author":"Girard C","year":"2008","journal-title":"Proc Natl Acad Sci USA."},{"issue":"Pt 6","key":"ref4","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1093\/brain\/awp128","article-title":"Polysialic acid glycomimetics promote myelination and functional recovery after peripheral nerve injury in mice","volume":"132","author":"Mehanna A","year":"2009","journal-title":"Brain."},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1002\/lsm.10098","article-title":"Quantitation of calcitonin gene-related peptide mRNA and Neuronal cell death in facial motor nuclei following axotomy and 633 nm low power laser","volume":"31","author":"Snyder SK","year":"2002","journal-title":"Lasers Surg Med."},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1089\/pho.2006.1090","article-title":"Promotion of regenerative processes in injured peripheral nerve induced by low-level laser therapy","volume":"25","author":"Mohammed IF","year":"2007","journal-title":"Photomed Laser Surg."},{"issue":"2","key":"ref7","first-page":"127","article-title":"Estudo comparativo entre dois tipos de raio laser de baixa pot\u00eancia e seus respectivos efeitos sobre a regenera\u00e7\u00e3o nervosa perif\u00e9rica","volume":"19","author":"Camargo VM","year":"2006","journal-title":"Fisioter Mov."},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s10103-008-0634-3","article-title":"Effect of laser therapy (660 nm) on recovery of the sciatic nerve in rats after injury through neurotmesis followed by epineural anastomosis","volume":"24","author":"Dos Reis FA","year":"2009","journal-title":"Lasers Med Sci."},{"issue":"5","key":"ref9","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1590\/S1413-78522008000500011","article-title":"A laserterapia de baixa intensidade acelera a regenera\u00e7\u00e3o de nervos perif\u00e9ricos","volume":"16","author":"Endo C","year":"2008","journal-title":"Acta Ortop. 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