{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:39:35Z","timestamp":1793061575712,"version":"4.5.0"},"reference-count":22,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:p>PURPOSE: To compare vitamin levels, inflammatory and oxidative stress markers before and after skin autograft surgery to correct burn scar areas. METHODS: This prospective study was conducted with 8 patients with a median age of 28 years (range, 16 to 40 years) that had burn sequelae and were admitted to a Burn Unit for correction of small burn scar areas [3.3 (1.0-5.0) % of the corporal surface]. The volunteers were evaluated before and 48 hours after excision of scar tissue and skin autograft. Routine laboratory data, along with a food questionnaire and anthropometry were collected in the preoperative period. Serum vitamin A, C, E, B12 and folic acid levels, inflammatory markers (C-protein reactive, alpha-1-acid glycoprotein, ferritin) and oxidative stress markers (reduced glutathione - GSH and Thiobarbituric Acid Reactive Substances - TBARS) were determined at preoperative and postoperative phases. Data were analyzed with two-sample Wilcoxon test. RESULTS: All volunteers were clinically stable and had adequate nutritional status at admission. After surgery, C-reactive protein serum levels increased [0.4 (0.01-1.0) vs. 2.5 (0.6-4.7) mg\/dL, p=0.01] and vitamin A levels decreased [3.4 (2.1-4.2) vs. 2.4 (1.6-4.1) \u00b5mol\/L, p=0.01]. No changes occurred in other vitamins, ferrritin, alpha-1-acid glycoprotein, GSH and TBARS levels. CONCLUSION: Minimal metabolic changes were produced after skin autograft in small areas of well-nourished patients without active infection or inflammation.<\/jats:p>","DOI":"10.1590\/s0102-86502011000400013","type":"journal-article","created":{"date-parts":[[2011,8,5]],"date-time":"2011-08-05T11:35:38Z","timestamp":1312544138000},"page":"320-324","source":"Crossref","is-referenced-by-count":5,"title":["Inflammatory and oxidative stress after surgery for the small area corrections of burn sequelae"],"prefix":"10.1590","volume":"26","author":[{"given":"Paula Pileggi","family":"Vinha","sequence":"first","affiliation":[{"name":"FMRP-USP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alceu Afonso","family":"Jord\u00e3o Jr","sequence":"additional","affiliation":[{"name":"FMRP-USP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayme Adriano","family":"Farina Jr","sequence":"additional","affiliation":[{"name":"FMRP-USP, 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