{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T08:22:00Z","timestamp":1773908520868,"version":"3.50.1"},"reference-count":12,"publisher":"FapUNIFESP (SciELO)","issue":"suppl 2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>PURPOSE: To evaluate the effects of metoclopramide on abdominal wall healing in rats in the presence of sepsis. METHODS: 40 rats divided into two groups of twenty animals, subdivided into two subgroups of 10 animals each: group (E) - treated with metoclopramide, and saline-treated control group. The two groups were divided into subgroups of 10 to be killed on the 3rd day (n = 10) or day 7 (n = 10) after surgery. Sepsis was induced by cecal ligation and puncture. We performed also the section and anastomosis in left colon. The synthesis of the abdominal wall was made with 3-0 silk thread. We measured the breaking strength of the abdominal wall and made the histopathological evaluation. RESULTS: on 3rd day postoperative, the average breaking strength in the E group was 0.83 \u00b1 0.66 and in group C was 0.35 \u00b1 0.46 (p = 0.010). On the seventh day, the breaking strength in group E was11.44 \u00b1 5.07, in group C 11.66 \u00b1 7.38 (p = 1.000). The E7 group showed lower inflammatory infiltration, foreign body reaction, fibrin than control. CONCLUSION: animals treated with metoclopramide had a higher resistance of the abdominal wall on the 3rd postoperative day.<\/jats:p>","DOI":"10.1590\/s0102-86502011000800017","type":"journal-article","created":{"date-parts":[[2011,10,26]],"date-time":"2011-10-26T01:19:25Z","timestamp":1319591965000},"page":"92-99","source":"Crossref","is-referenced-by-count":4,"title":["Influence of metoclopramide on abdominal wall healing in rats subjected to colonic anastomosis in the presence of peritoneal sepsis induced"],"prefix":"10.1590","volume":"26","author":[{"given":"Naiara Galv\u00e3o da","family":"Silva","sequence":"first","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre Malta","family":"Brand\u00e3o","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Vin\u00edcius Melo de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Henrique Alves de","family":"Morais","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana Marques e","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana Pirani","family":"Carneiro","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Batista de","family":"Sousa","sequence":"additional","affiliation":[{"name":"UnB,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1:35","DOI":"10.1590\/S0034-70942008000100005","article-title":"Profilaxia Antiem\u00e9tica em Cirurgia de Abdome Agudo. 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