{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T01:01:37Z","timestamp":1705539697058},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p>PURPOSE: To compare gene expression of the chemokines RANTES and eotaxin-2, its receptor, CCR-3, adhesion molecule ICAM-1 and its receptor LFA-1 in eosinophilic polyps and in control normal nasal mucosa. METHODS: Gene expression was quantified by Real Time PCR in polyps (n=35) and in healthy nasal mucosa (n=15). RESULTS: Eosinophilic polyps showed a higher expression of eotaxin-2 and RANTES, but not of CCR-3, ICAM-1 or LFA-1 compared to control nasal mucosa. CONCLUSION: Eosinophilic polyps present greater expression of eotaxin-2 and RANTES, but not of CCR-3, ICAM-1 or LFA-1 compared to control nasal mucosa.<\/jats:p>","DOI":"10.1590\/s0102-86502012000900010","type":"journal-article","created":{"date-parts":[[2012,8,29]],"date-time":"2012-08-29T03:29:48Z","timestamp":1346210988000},"page":"645-649","source":"Crossref","is-referenced-by-count":9,"title":["Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis"],"prefix":"10.1590","volume":"27","author":[{"given":"Frans\u00e9rgio Em\u00edlio","family":"Cavallari","sequence":"first","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana Cardoso Pereira","family":"Valera","sequence":"additional","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Jorge","family":"Gallego","sequence":"additional","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael Rossell","family":"Malinsky","sequence":"additional","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Salgado","family":"K\u00fcpper","sequence":"additional","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiane","family":"Milanezi","sequence":"additional","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Santana da","family":"Silva","sequence":"additional","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin","family":"Tamashiro","sequence":"additional","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilma Terezinha","family":"Anselmo-Lima","sequence":"additional","affiliation":[{"name":"USP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.2500\/105065800781329573","article-title":"Nasal polyposis: from cytokines to growth","volume":"14","author":"Bachert C","year":"2000","journal-title":"Am J Rhinol","ISSN":"http:\/\/id.crossref.org\/issn\/1050-6586","issn-type":"print"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/MOO.0b013e3282f363f1","article-title":"Inflammatory genes in nasal polyposis","volume":"16","author":"Figueiredo CR","year":"2008","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/sj.gene.6363881","article-title":"Cytokine gene polymorphism in human disease: online databases, supplement 2","volume":"3","author":"Haukim N","year":"2002","journal-title":"Genes Immun"},{"key":"ref4","author":"Shin SH"},{"issue":"9","key":"ref5","doi-asserted-by":"crossref","first-page":"877","DOI":"10.4065\/74.9.877","article-title":"The diagnosis and incidence of allergic fungal sinusitis","volume":"74","author":"Ponikau JU","year":"1999","journal-title":"Mayo Clean Proc"},{"issue":"3","key":"ref6","first-page":"178","article-title":"The fungal debate: where do we stand today","volume":"45","author":"Ebbens FA","year":"2007","journal-title":"Rhinology","ISSN":"http:\/\/id.crossref.org\/issn\/0300-0729","issn-type":"print"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1590\/S1413-86702009000300015","article-title":"Implications of bacterial biofilms in chronic rhinosinusitis","volume":"13","author":"Tamashiro E","year":"2009","journal-title":"Braz J Infect Dis"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/MOO.0b013e3282fb2885","article-title":"The role of cytokines in chronic rhinosinusitis with nasal polyps","volume":"16","author":"Otto BA","year":"2008","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1177\/000348949810700510","article-title":"Characterization of the eosinophil chemokine RANTES in nasal polyps","volume":"107","author":"Allen JS","year":"1998","journal-title":"Ann Otol Rhinol Laryngol","ISSN":"http:\/\/id.crossref.org\/issn\/0003-4894","issn-type":"print"},{"issue":"3","key":"ref10","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s00405-005-1031-1","article-title":"Interleukin 5, IL6, IL12, IFN gamma, RANTES and fractalkine in human nasal polyps, turbinate mucosa and serum","volume":"263","author":"Danielsen A","year":"2006","journal-title":"Eur Arch Otorhinolaryngol","ISSN":"http:\/\/id.crossref.org\/issn\/0937-4477","issn-type":"print"},{"issue":"4","key":"ref11","first-page":"171","article-title":"Increased eotaxin mRNA expression in non atopic and atopic nasal polyps: comparison to RANTES and MCP3 expression","volume":"35","author":"Bartels J","year":"1997","journal-title":"Rhinology","ISSN":"http:\/\/id.crossref.org\/issn\/0300-0729","issn-type":"print"},{"issue":"1","key":"ref12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/194589240501900103","article-title":"The role of RANTES in nasal polyposis","volume":"19","author":"Meyer JE","year":"2005","journal-title":"Am J Rhinol","ISSN":"http:\/\/id.crossref.org\/issn\/1050-6586","issn-type":"print"},{"issue":"8","key":"ref13","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1097\/00005537-200008000-00025","article-title":"Quantitative analysis of eotaxin and RANTES Messenger RNA in nasal polyps: association of tissue and nasal eosinophils","volume":"110","author":"Shin SH","year":"2000","journal-title":"Laryngoscope","ISSN":"http:\/\/id.crossref.org\/issn\/0023-852X","issn-type":"print"},{"key":"ref14","first-page":"145","article-title":"Eosinophilic nasal polyps are a rich source of eotaxin, eotaxin 2 and eotaxin 3","volume":"44","author":"Olze H","year":"2006","journal-title":"Rhinology","ISSN":"http:\/\/id.crossref.org\/issn\/0300-0729","issn-type":"print"},{"issue":"1","key":"ref15","doi-asserted-by":"crossref","first-page":"11","DOI":"10.2500\/ajra.2010.24.3386","article-title":"Evaluation of the presence of B cell attractant chemokines in chronic rhinosinusitis","volume":"24","author":"Patadia M","year":"2010","journal-title":"Am J Rhinol Allergy"},{"issue":"23","key":"ref16","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0165-2478(03)00163-9","article-title":"Transcription and translation of the chemokines RANTES and MCP1 in nasal polyps and mucosa in allergic and non allergic rhinopathies","volume":"90","author":"Marcella R","year":"2003","journal-title":"Immunol Lett","ISSN":"http:\/\/id.crossref.org\/issn\/0165-2478","issn-type":"print"},{"issue":"2","key":"ref17","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1177\/194589240602000203","article-title":"Altered expression of genes associated with innate immunity and inflammation in recalcitrant rhinosinusitis with polyps","volume":"20","author":"Lane AP","year":"2006","journal-title":"Am J Rhinol","ISSN":"http:\/\/id.crossref.org\/issn\/1050-6586","issn-type":"print"},{"issue":"6","key":"ref18","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1002\/lary.20191","article-title":"Eotaxin-1, -2, and -3 immunoreactivity and protein concentration in the nasal polyps of eosinophilic chronic rhinosinusitis patients","volume":"119","author":"Yao T","year":"2009","journal-title":"Laryngoscope","ISSN":"http:\/\/id.crossref.org\/issn\/0023-852X","issn-type":"print"},{"issue":"6","key":"ref19","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.otohns.2007.07.036","article-title":"Histological and immunological features of non eosinophilic nasal polyps","volume":"137","author":"Kim JW","year":"2007","journal-title":"Otolaryngol Head Neck Surg","ISSN":"http:\/\/id.crossref.org\/issn\/0194-5998","issn-type":"print"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"115","DOI":"10.5301\/JBM.2008.3575","article-title":"Protein biochip array of adhesion molecule expression in peripheral blood of patients with nasal polyposis","volume":"23","author":"Corsi MM","year":"2008","journal-title":"Int J Biol Markers","ISSN":"http:\/\/id.crossref.org\/issn\/0393-6155","issn-type":"print"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1590\/S0034-72992008000700002","article-title":"Diretrizes Brasileiras de Rinossinusites","volume":"74","author":"Ara\u00fajo E","year":"2008","journal-title":"Rev Bras Otorrinolaringol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0091-6749(97)80019-X","article-title":"Il5 synthesis is upregulated in human nasal polyp tissue","volume":"99","author":"Bachert C","year":"1997","journal-title":"J Allergy Clin Immunol","ISSN":"http:\/\/id.crossref.org\/issn\/0091-6749","issn-type":"print"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1067\/mai.2001.112374","article-title":"Total and specific IgE in nasal polyps is related to local eosinophilic inflammation","volume":"107","author":"Bachert C","year":"2001","journal-title":"J Allergy Clin Immunol","ISSN":"http:\/\/id.crossref.org\/issn\/0091-6749","issn-type":"print"},{"issue":"4","key":"ref24","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1365-2222.2007.02929.x","article-title":"Expression of transcription factors NF-kappaB and AP-1 in nasal polyposis","volume":"38","author":"Valera FC","year":"2008","journal-title":"Clin Exp Allergy","ISSN":"http:\/\/id.crossref.org\/issn\/0954-7894","issn-type":"print"},{"issue":"4","key":"ref25","first-page":"607","article-title":"Expression of adhesion molecule ICAM-1 in patients with nasal polyps","volume":"61","author":"Olejniczak I","year":"2007","journal-title":"Otolaryngol Pol","ISSN":"http:\/\/id.crossref.org\/issn\/0030-6657","issn-type":"print"}],"container-title":["Acta Cirurgica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/acb\/v27n9\/v27n9a10.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T01:39:15Z","timestamp":1562117955000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-86502012000900010&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":25,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S0102-86502012000900010"],"URL":"https:\/\/doi.org\/10.1590\/s0102-86502012000900010","relation":{},"ISSN":["0102-8650"],"issn-type":[{"value":"0102-8650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}