{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T07:42:13Z","timestamp":1777362133617,"version":"3.51.4"},"reference-count":29,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1590\/s0102-865020150060000007","type":"journal-article","created":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T20:34:08Z","timestamp":1489610048000},"page":"414-421","source":"Crossref","is-referenced-by-count":25,"title":["The antioxidant effect of dexmedetomidine on testicular ischemia-reperfusion injury"],"prefix":"10.1590","volume":"30","author":[{"given":"Devrim","family":"Tuglu","sequence":"first","affiliation":[{"name":"University of Kirikkale, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ercan","family":"Yuvanc","sequence":"additional","affiliation":[{"name":"University of Kirikkale, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erdal","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"University of Kirikkale, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isin Yazici","family":"Gencay","sequence":"additional","affiliation":[{"name":"University of Kirikkale, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinar","family":"Atasoy","sequence":"additional","affiliation":[{"name":"University of Kirikkale, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ucler","family":"Kisa","sequence":"additional","affiliation":[{"name":"University of Kirikkale, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ertan","family":"Batislam","sequence":"additional","affiliation":[{"name":"University of Kirikkale, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"1","key":"ref1","first-page":"38","article-title":"Testicular torsion: a review","volume":"5","author":"Pentyala S","year":"2001","journal-title":"J Low Genit Tract Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/bjs.1800720702","article-title":"The continuing conundrum of testicular torsion","volume":"72","author":"Williamson RC","year":"1985","journal-title":"Br J Surg"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/BF00300075","article-title":"Reperfusion injury after detorsion of unilateral testicular torsion","volume":"21","author":"Akgur FM","year":"1993","journal-title":"Urol Res"},{"issue":"1-2","key":"ref4","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.mam.2004.02.020","article-title":"Spermatic cord torsion, reactive oxygen and nitrogen species and ischemia-reperfusion injury","volume":"25","author":"Filho DW","year":"2004","journal-title":"Mol Aspects Med"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0031-6997(24)01484-4","article-title":"Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia\/reperfusion injury","volume":"53","author":"Cuzzocrea S","year":"2001","journal-title":"Pharmacol Rev"},{"issue":"3","key":"ref6","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.yexmp.2010.07.006","article-title":"Protective effects of melatonin on testicular torsion\/detorsion-induced ischemia-reperfusion injury in rats","volume":"89","author":"Kanter M","year":"2010","journal-title":"Exp Mol Pathol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1213\/01.ane.0000197777.62397.d5","article-title":"A comparison of Dexmedetomidine versus conventional therapy for sedation and hemodynamic control during carotid endarterectomy performed under regional anesthesia","volume":"102","author":"Mc Cutcheon CA","year":"2006","journal-title":"Anesth Analg"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1097\/00000542-200409000-00028","article-title":"Dexmedetomidine as a total intravenous anesthetic agent","volume":"101","author":"Ramsay MA","year":"2004","journal-title":"Anesthesiology"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1159\/000273476","article-title":"Effect of Dexmedetomidine on testicular torsion\/detorsion damage in rats","volume":"84","author":"Hanci V","year":"2010","journal-title":"Urol Int"},{"key":"ref10","first-page":"2","article-title":"Testicular biopsy score count-a method for registration of spermatogenesis in human testes: normal values and results of 335 hypogonadal males","volume":"1","author":"Johnsen SG","year":"1970","journal-title":"Hormones"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.clinbiochem.2003.10.014","article-title":"A novel automated method to measure total antioxidant response against potent free radical reactions","volume":"37","author":"Erel O","year":"2004","journal-title":"Clin Biochem"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.clinbiochem.2005.08.008","article-title":"A new automated colorimetric method for measuring total oxidant status","volume":"38","author":"Erel O","year":"2005","journal-title":"Clin Biochem"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1100\/2012\/489248","article-title":"The Effects of a-lipoic acid against testicular ischemia-reperfusion injury in rats","volume":"489248","author":"Ozbal S","year":"2012","journal-title":"Sci World J"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1007\/s00383-005-1365-1","article-title":"The protective effect of selenium on ipsilateral and contralateral testes in testicular reperfusion injury","volume":"21","author":"Avlan D","year":"2005","journal-title":"Pediatr Surg Int"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1097\/00000542-199108000-00022","article-title":"Dexmedetomidine improves neurologic outcome from incomplete ischemia in the rat. Reversal by the alpha 2-adrenergic antagonist atipamezole","volume":"75","author":"Hoffman WE","year":"1991","journal-title":"Anesthesiology"},{"issue":"2","key":"ref16","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/00000542-199308000-00016","article-title":"Neuroprotection by the alpha 2-adrenoreceptor agonist Dexmedetomidine in a focal model of cerebral ischemia","volume":"79","author":"Maier C","year":"1993","journal-title":"Anesthesiology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1097\/01.CCM.0000128579.84228.2A","article-title":"Effects of Dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in rats","volume":"32","author":"Taniguchi T","year":"2004","journal-title":"Crit Care Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1111\/j.1399-6576.2009.02019.x","article-title":"Effects of Dexmedetomidine or methylprednisolone on inflammatory responses in spinal cord injury","volume":"53","author":"Can M","year":"2009","journal-title":"Acta Anaesthesiol Scand"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1213\/00000539-199902000-00042","article-title":"The effects of clonidine and Dexmedetomidine on human neutrophil functions","volume":"88","author":"Nishina K","year":"1999","journal-title":"Anesth Analg"},{"issue":"5","key":"ref20","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1097\/ALN.0b013e3182503964","article-title":"Dexmedetomidine administration before, but not after, ischemia attenuates intestinal injury induced by intestinal ischemia-reperfusion in rats","volume":"116","author":"Zhang XY","year":"2012","journal-title":"Anesthesiology"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1080\/08860220802546487","article-title":"Effect of Dexmedetomidine on ischemia-reperfusion injury in rat kidney: a histopathologic study","volume":"31","author":"Kocoglu H","year":"2009","journal-title":"Ren Fail"},{"issue":"3","key":"ref22","doi-asserted-by":"crossref","first-page":"R153","DOI":"10.1186\/cc10283","article-title":"Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice","volume":"15","author":"Gu J","year":"2011","journal-title":"Crit Care"},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"F741","DOI":"10.1152\/ajprenal.90244.2008","article-title":"Alpha2-Adrenergic agonists protect against radiocontrast-induced nephropathy in mice","volume":"295","author":"Billings FT 4th","year":"2008","journal-title":"Am J Physiol Renal Physiol"},{"issue":"4","key":"ref24","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1590\/S0102-86502007000400011","article-title":"Renal function and histology after acute hemorrhage in rats under Dexmedetomidine action","volume":"22","author":"Marangoni MA","year":"2007","journal-title":"Acta Cir Bras"},{"key":"ref25","first-page":"429","article-title":"Effects of Dexmedetomidine on renal system and on vasopressin plasma levels. Experimental study in dogs","volume":"55","author":"Villela NR","year":"2005","journal-title":"Rev Bras Anestesiol"},{"issue":"3","key":"ref26","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1590\/S0102-86502011000300008","article-title":"Dexmedetomidine and S(+) - ketamine in ischemia and reperfusion injury in the rat kidney","volume":"26","author":"Curtis FG","year":"2011","journal-title":"Acta Cir Bras"},{"issue":"4","key":"ref27","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1093\/aje\/154.4.348","article-title":"Correlates of markers of oxidative status in the general population","volume":"154","author":"Trevisan M","year":"2001","journal-title":"Am J Epidemiol"},{"issue":"11","key":"ref28","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1007\/s11064-008-9730-9","article-title":"Effects of acrylamide on the nervous tissue antioxidant system and sciatic nerve electrophysiology in the rat","volume":"33","author":"Zhu YJ","year":"2008","journal-title":"Neurochem Res"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00240-004-0418-6","article-title":"The effect of sustained and local administration of epidermal growth factor on improving bilateral testicular tissue after torsion","volume":"32","author":"Uguralp S","year":"2004","journal-title":"Urol Res"}],"container-title":["Acta Cirurgica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/acb\/v30n6\/0102-8650-acb-30-06-00414.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T22:14:22Z","timestamp":1750112062000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-86502015000600414&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S0102-86502015000600414"],"URL":"https:\/\/doi.org\/10.1590\/s0102-865020150060000007","relation":{},"ISSN":["0102-8650"],"issn-type":[{"value":"0102-8650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6]]}}}