{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:44:58Z","timestamp":1772585098823,"version":"3.50.1"},"reference-count":28,"publisher":"FapUNIFESP (SciELO)","issue":"suppl 1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"published-print":{"date-parts":[[2016]]},"DOI":"10.1590\/s0102-86502016001300005","type":"journal-article","created":{"date-parts":[[2016,4,27]],"date-time":"2016-04-27T23:41:05Z","timestamp":1461800465000},"page":"19-23","source":"Crossref","is-referenced-by-count":25,"title":["Adjunctive Hyperbaric Oxygen Therapy promotes successful healing in patients with refractory Crohn's disease"],"prefix":"10.1590","volume":"31","author":[{"given":"Marley Ribeiro","family":"Feitosa","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"F\u00e9res Filho","sequence":"additional","affiliation":[{"name":"Bar\u00e3o de Mau\u00e1 University Center, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila Mussolin","family":"Tamaki","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo Hospital, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila","family":"Perazzoli","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rio Vin\u00edcius Angelete Alvarez","family":"Bernardes","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rog\u00e9rio Serafim","family":"Parra","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Joaquim Ribeiro da","family":"Rocha","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"F\u00e9res","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"6","key":"ref1","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1053\/j.gastro.2004.02.072","article-title":"From symptom to diagnosis: clinical distinctions among various forms of intestinal inflammation","volume":"126","author":"Sands BE","year":"2004","journal-title":"Gastroenterology"},{"issue":"5","key":"ref2","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1080\/00365520601076124","article-title":"Clinical course in Crohn's disease: results of a five-year population-based follow-up study (the IBSEN study)","volume":"42","author":"Henriksen M","year":"2007","journal-title":"Scand J Gastroenterol"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/ajg.2008.168","article-title":"Management of Crohn's disease in adults","volume":"104","author":"Lichtenstein GR","year":"2009","journal-title":"The American journal of gastroenterology"},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1590\/S0102-86502011000800024","article-title":"Crohn's disease and hyperbaric oxygen therapy","volume":"26","author":"Iezzi LE","year":"2011","journal-title":"Acta Cir Bras"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1097\/00004836-199410000-00006","article-title":"Hyperbaric oxygen for perianal Crohn's disease","volume":"19","author":"Lavy A","year":"1994","journal-title":"J Clin Gastroenterol"},{"issue":"6","key":"ref6","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/BF02054120","article-title":"Hyperbaric oxygenation in severe perineal Crohn's disease","volume":"38","author":"Colombel JF","year":"1995","journal-title":"Dis Colon Rectum"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/00004836-199510000-00010","article-title":"Six patients whose perianal and ileocolic Crohn's disease improved in the Dead Sea environment","volume":"21","author":"Fraser GM","year":"1995","journal-title":"J Clin Gastroenterol"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1023\/A:1027378532003","article-title":"Modification of in vivo and in vitro TNF-alpha, IL-1, and IL-6 secretion by circulating monocytes during hyperbaric oxygen treatment in patients with perianal Crohn's disease","volume":"17","author":"Weisz G","year":"1997","journal-title":"J Cin Immunol"},{"issue":"6","key":"ref9","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/j.1524-475X.2005.00078.x","article-title":"Hyperoxia and angiogenesis","volume":"13","author":"Hopf HW","year":"2005","journal-title":"Wound Repair Regen"},{"issue":"11","key":"ref10","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1089\/ars.2014.5940","article-title":"Hyperbaric oxygen, vasculogenic stem cells, and wound healing","volume":"21","author":"Fosen KM","year":"2014","journal-title":"Antioxid Redox Signal"},{"issue":"1","key":"ref11","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1046\/j.1365-2249.2003.02248.x","article-title":"Hyperbaric oxygen inhibits stimulus-induced proinflammatory cytokine synthesis by human blood-derived monocyte-macrophages","volume":"134","author":"Benson RM","year":"2003","journal-title":"Clin Exp Immunol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13618-015-0026-2","article-title":"Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats","volume":"5","author":"Parra RS","year":"2015","journal-title":"Med Gas Res"},{"issue":"6692","key":"ref13","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/28867","article-title":"Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis","volume":"394","author":"Carmeliet P","year":"1998","journal-title":"Nature"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.pmrj.2009.03.012","article-title":"Hyperbaric oxygen therapy for wound healing and limb salvage: a systematic review","volume":"1","author":"Goldman RJ","year":"2009","journal-title":"PM R"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/0016-5085(89)90649-5","article-title":"Healing of severe perineal and cutaneous Crohn's disease with hyperbaric oxygen","volume":"97","author":"Brady 3rd CE","year":"1989","journal-title":"Gastroenterology"},{"issue":"4","key":"ref16","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/0016-5085(79)90391-3","article-title":"National Cooperative Crohn's Disease Study: extraintestinal manifestations and perianal complications","volume":"77","author":"Rankin GB","year":"1979","journal-title":"Gastroenterology"},{"issue":"5","key":"ref17","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00384-009-0638-x","article-title":"Long-term success rate after surgical treatment of anorectal and rectovaginal fistulas in Crohn's disease","volume":"24","author":"Loffler T","year":"2009","journal-title":"Int J Colorectal Dis"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0016-5085(80)90155-9","article-title":"Healing of perineal Crohn's disease with metronidazole","volume":"79","author":"Bernstein LH","year":"1980","journal-title":"Gastroenterology"},{"issue":"11-12","key":"ref19","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1046\/j.1365-2036.2003.01793.x","article-title":"Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease","volume":"18","author":"Dejaco C","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"issue":"4","key":"ref20","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1590\/S0004-28032014000400004","article-title":"Perianal complete remission with combined therapy (seton placement and anti-TNF agents) in Crohn's disease: a Brazilian multicenter observational study","volume":"51","author":"Kotze PG","year":"2014","journal-title":"Arq Gastroenterol"},{"issue":"8","key":"ref21","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.cgh.2012.12.042","article-title":"Long-term outcome of perianal fistulizing Crohn's disease treated with infliximab","volume":"11","author":"Bouguen G","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"10","key":"ref22","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.dld.2007.07.157","article-title":"Surgical therapy of perianal Crohn's disease","volume":"39","author":"Singh B","year":"2007","journal-title":"Dig Liver Dis"},{"issue":"1","key":"ref23","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1001\/archfaci.6.1.31","article-title":"Effect of hyperbaric oxygen on the growth factor profile of fibroblasts","volume":"6","author":"Kang TS","year":"2004","journal-title":"Arch Facial Plast Surg"},{"issue":"4","key":"ref24","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1182\/blood-2004-04-1559","article-title":"Human mesenchymal stem cells modulate allogeneic immune cell responses","volume":"105","author":"Aggarwal S","year":"2005","journal-title":"Blood"},{"issue":"9","key":"ref25","first-page":"1241","article-title":"Hyperbaric oxygen therapy accelerates vascularization in keratinized oral mucosal surgical flaps","volume":"36","author":"Helmers R","year":"2014","journal-title":"Head Neck"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1746-160X-6-29","article-title":"The impact of hyperbaric oxygen therapy on serological values of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF)","volume":"6","author":"Jung S","year":"2010","journal-title":"Head Face Med"},{"issue":"6","key":"ref27","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1590\/S0365-05962011000600022","article-title":"Hyperbaric oxygen therapy as an adjuvant treatment for pyoderma gangrenosum","volume":"86","author":"Vieira WA","year":"2011","journal-title":"An Bras Dermatol"},{"issue":"2","key":"ref28","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1159\/000353373","article-title":"Perforating Crohn's disease: conservative and surgical treatment","volume":"31","author":"Sampietro GM","year":"2013","journal-title":"Dig Dis"}],"container-title":["Acta Cirurgica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/acb\/v31s1\/0102-8650-acb-31-s1-00019.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,7]],"date-time":"2019-09-07T02:48:03Z","timestamp":1567824483000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-86502016001300019&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":28,"journal-issue":{"issue":"suppl 1","published-print":{"date-parts":[[2016]]}},"alternative-id":["S0102-86502016001300019"],"URL":"https:\/\/doi.org\/10.1590\/s0102-86502016001300005","relation":{},"ISSN":["0102-8650"],"issn-type":[{"value":"0102-8650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}