{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T11:09:26Z","timestamp":1763896166111,"version":"3.41.2"},"reference-count":33,"publisher":"FapUNIFESP (SciELO)","issue":"9","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"DOI":"10.1590\/s0102-865020200090000005","type":"journal-article","created":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T20:04:24Z","timestamp":1603137864000},"source":"Crossref","is-referenced-by-count":3,"title":["The examination of the nephroprotective effect of montelukast sodium and N-acetylcysteine \u0131n renal \u0131schemia with dimercaptosuccinic acid imaging in a placebo-controlled rat model"],"prefix":"10.1590","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8691-090X","authenticated-orcid":false,"given":"Arif","family":"Aydin","sequence":"first","affiliation":[{"name":"NE\u00dc Meram Medicine Faculty,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1917-927X","authenticated-orcid":false,"given":"Mehmet Melih","family":"Sunay","sequence":"additional","affiliation":[{"name":"Karab\u00fck University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6694-8369","authenticated-orcid":false,"given":"Tolga","family":"Karakan","sequence":"additional","affiliation":[{"name":"Ankara Training and Research Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2459-139X","authenticated-orcid":false,"given":"Serkan","family":"\u00d6zcan","sequence":"additional","affiliation":[{"name":"\u0130zmir Katip \u00c7elebi University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2137-4530","authenticated-orcid":false,"given":"Ahmet Metin","family":"Has\u00e7i\u00e7ek","sequence":"additional","affiliation":[{"name":"Ankara Training and Research Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2784-5631","authenticated-orcid":false,"given":"\u0130brahim","family":"Yardimci","sequence":"additional","affiliation":[{"name":"Adana \u00c7ukurova State Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6899-3115","authenticated-orcid":false,"given":"Hatice","family":"Surer","sequence":"additional","affiliation":[{"name":"Ankara Training and Research Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3251-3738","authenticated-orcid":false,"given":"Meliha","family":"Korkmaz","sequence":"additional","affiliation":[{"name":"Ankara Training and Research Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6898-4101","authenticated-orcid":false,"given":"Sema","family":"H\u00fcc\u00fcmeno\u011flu","sequence":"additional","affiliation":[{"name":"Ankara Training and Research Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5563-4527","authenticated-orcid":false,"given":"Emre","family":"Huri","sequence":"additional","affiliation":[{"name":"Hacettepe University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"41","key":"ref1","doi-asserted-by":"crossref","first-page":"14883","DOI":"10.1073\/pnas.0406421101","article-title":"Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury","volume":"101","author":"Hamar P","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref2","first-page":"R922","article-title":"Early kidney TNF-\u03b1 expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion","volume":"277","author":"Donnahoo KK","year":"1999","journal-title":"Am J Physiol"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1046\/j.1523-1755.2001.060002786.x","article-title":"Endothelial cell protection against ischemia\/reperfusion injury by lecithinized superoxide dismutase","volume":"60","author":"Koo DD","year":"2001","journal-title":"Kidney Int"},{"issue":"9","key":"ref4","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1016\/j.transproceed.2015.09.035","article-title":"N-acetylcysteine and high-dose atorvastatin reduce oxidative stress in an \u0131schemia-reperfusion model in the rat kidney","volume":"47","author":"Cusumano G","year":"2015","journal-title":"Transplant Proc"},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.2298\/SARH160301031S","article-title":"Scintigraphic, histopathologic and biochemical evaluation of lycopene effects on renal ischemia reperfusion injury in rats","volume":"145","author":"Sadic M","year":"2017","journal-title":"Srpski arhiv za celokupno lekarstvo"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.phrs.2006.02.007","article-title":"Montelukast protects against renal ischemia\/reperfusion injury in rats","volume":"54","author":"Sener G","year":"2006","journal-title":"Pharmacol Res"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1056-8719(96)00141-4","article-title":"Characterization of renal ischemia-reperfusion injury in rats","volume":"37","author":"Williams P","year":"1997","journal-title":"J Pharmacol Toxicol Methods"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1146\/annurev.ph.57.030195.001523","article-title":"Physiological mechanisms of post-ischemic tissue injury","volume":"57","author":"Granger DN","year":"1995","journal-title":"Annu Rev Physiol"},{"issue":"6","key":"ref9","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1172\/JCI116491","article-title":"Hypercholesterolemia increases endothelial superoxide anion production","volume":"91","author":"Ohara Y","year":"1993","journal-title":"J Clin Invest"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1136\/gut.35.2.179","article-title":"Helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo","volume":"35","author":"Davies GR","year":"1994","journal-title":"Gut"},{"issue":"6","key":"ref11","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/j.1472-8206.2004.00279.x","article-title":"Carvedilol attenuates ischemia-reperfusion-induced oxidative renal injury in rats","volume":"18","author":"Singh D","year":"2004","journal-title":"Fundam Clin Pharmacol"},{"issue":"2","key":"ref12","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0022-5347(05)68626-0","article-title":"In situ detection of lipid peroxidation by-products as markers of renal ischemia injuries in rat kidneys","volume":"162","author":"Eschwege P","year":"1999","journal-title":"J Urol"},{"issue":"6","key":"ref13","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.phrs.2004.06.006","article-title":"Effect of trimetazidine on renal ischemia\/reperfusion injury in rats","volume":"50","author":"Singh D","year":"2004","journal-title":"Pharmacol Res"},{"issue":"2","key":"ref14","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S0272-6386(99)70375-6","article-title":"Neutrophils and renal failure","volume":"34","author":"Heinzelmann M","year":"1999","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"ref15","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jss.2003.07.004","article-title":"Role of leukotrienes on hepatic ischemia\/reperfusion injury in rats","volume":"119","author":"Takamatsu Y","year":"2004","journal-title":"J Surg Res"},{"issue":"4","key":"ref16","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/jcbfm.1991.115","article-title":"Intracarotid infusion of leukotriene C4 selectively increases blood\u2013brain barrier permeability after focal ischemia in rats","volume":"11","author":"Baba T","year":"1991","journal-title":"J Cereb Blood Flow Metab"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000081072","article-title":"Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal ischemia in mice","volume":"73","author":"Yu GL","year":"2005","journal-title":"Pharmacology"},{"issue":"1","key":"ref18","first-page":"1","article-title":"Protective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 in rats","volume":"39","author":"Zhang SH","year":"2004","journal-title":"Yao Xue Xue Bao"},{"issue":"2","key":"ref19","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1124\/mol.66.2.220","article-title":"Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton","volume":"66","author":"Patel NS","year":"2004","journal-title":"Mol Pharmacol"},{"issue":"8","key":"ref20","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1055\/s-2005-871252","article-title":"Protective effect of the 5-lipoxygenase inhibitor ardisiaquinone on hepatic ischemia-reperfusion injury in rats","volume":"71","author":"Matsui N","year":"2005","journal-title":"Planta Med"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0014-2999(02)01313-4","article-title":"Effect of a BLT receptor antagonist in a model of severe ischemia and reperfusion injury in the rat","volume":"440","author":"Souza DG","year":"2002","journal-title":"Eur J Pharmacol"},{"issue":"2","key":"ref22","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1073\/pnas.97.2.823","article-title":"An in vivo approach showing the chemotactic activity of leukotriene B4 in acute renal ischemic-reperfusion injury","volume":"97","author":"Noiri E","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"ref23","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1172\/JCI116356","article-title":"Leukotriene D4 is a mediator of proteinuria and glomerular hemodynamic abnormalities in passive Heymann nephritis","volume":"91","author":"Katoh T","year":"1993","journal-title":"J Clin Invest"},{"issue":"5","key":"ref24","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1111\/j.1523-1755.2005.00276.x","article-title":"The ATP-sensitive potassium channel blocker gliben-clamide prevents renal ischemia\/reperfusion injury in rats","volume":"67","author":"Pompermayer K","year":"2005","journal-title":"Kidney Int"},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"L137","DOI":"10.1152\/ajplung.00261.2003","article-title":"Cytokine mRNA expression in unilateral ischemic-reperfused rat lung with salt solution supplemented with low-endotoxin or standard bovine serum albumin","volume":"286","author":"Teng S","year":"2004","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"3","key":"ref26","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jtcvs.2005.02.035","article-title":"Aprotinin improves kidney function and decreases tubular cell apoptosis and proapoptotic signaling after renal ischemia-reperfusion","volume":"130","author":"Kher A","year":"2005","journal-title":"J Thorac Cardiovasc"},{"issue":"1","key":"ref27","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1476-5381.2008.00012.x","article-title":"Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism","volume":"156","author":"Anderson R","year":"2009","journal-title":"Br J Pharmacol"},{"issue":"6","key":"ref28","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1590\/S0102-86502010000600006","article-title":"Effect of sildenafil in renal ischemia\/reperfusion injury in rats","volume":"25","author":"Medeiros PJ","year":"2010","journal-title":"Acta Cir Bras"},{"issue":"6","key":"ref29","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/s12272-001-1216-3","article-title":"Melatonin treatment against remote organ injury induced by renal ischemia reperfusion injury in diabetes mellitus","volume":"31","author":"Fadillioglu E","year":"2008","journal-title":"Arch Pharm Res"},{"issue":"2","key":"ref30","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jss.2008.07.031","article-title":"Montelukast protects axial pattern rat skin flaps against ischemia\/reperfusion injury","volume":"157","author":"Gideroglu K","year":"2009","journal-title":"J Surg Res"},{"issue":"6","key":"ref31","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1211\/jpp.59.6.0009","article-title":"Montelukast reduces ischaemia\/reperfusion-induced bladder dysfunction and oxidant damage in the rat","volume":"59","author":"Sener G","year":"2007","journal-title":"J Pharm Pharmacol"},{"issue":"1","key":"ref32","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00240-005-0031-3","article-title":"Protein oxidation and lipid peroxidation after renal ischemia-reperfusion injury: protective effects of erdosteine and N-acetylcysteine","volume":"34","author":"Erdogan H","year":"2006","journal-title":"Urol Res"},{"issue":"1","key":"ref33","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3906\/sag-1310-38","article-title":"Protective effects of erdosteine, vitamin E, and vitamin C on renal injury induced by the ischemia-reperfusion of the hind limbs in rats","volume":"45","author":"Sirmali R","year":"2015","journal-title":"Turk J Med Sci"}],"container-title":["Acta Cir\u00fargica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/acb\/v35n9\/1678-2674-acb-35-9-e202000905.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T01:08:56Z","timestamp":1611450536000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-86502020000900204&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":33,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020]]}},"alternative-id":["S0102-86502020000900204"],"URL":"https:\/\/doi.org\/10.1590\/s0102-865020200090000005","relation":{},"ISSN":["1678-2674","0102-8650"],"issn-type":[{"type":"electronic","value":"1678-2674"},{"type":"print","value":"0102-8650"}],"subject":[],"published":{"date-parts":[[2020]]},"article-number":"e202000905"}}