{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T01:45:50Z","timestamp":1768527950181,"version":"3.49.0"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>There has been an increase in the incidence of carcinoma of the tongue, particularly among alcohol and tobacco non-users. However, the number of studies that would allow a better understanding of etiological factors and clinical features, particularly in the Portuguese population, is very limited. This study was based on patients with squamous cell carcinoma of the anterior two thirds of the tongue that were treated at the Department of Head and Neck Surgery of the \u201cInstituto Portugues de Oncologia de Lisboa - Francisco Gentil\u201d (IPOLFG) in Lisbon, Portugal, between January 1, 2001 and December 31, 2009. The patients were divided in alcohol and tobacco users and non-users in order to evaluate the differences between these 2 groups based on gender, age, tumor location, denture use, and tumor size, metastasis and stage. Of the 354 cases, 208 were users and 146 were non-users. The main location in both groups was the lateral border of the tongue. Denture use showed no significant effect in both study groups. It was possible to conclude that patients who did not drink or smoke were older and presented with smaller tumor size, lower incidence of ganglion metastasis and lower tumor stage compared with alcohol and tobacco users.<\/jats:p>","DOI":"10.1590\/s0103-64402011000600013","type":"journal-article","created":{"date-parts":[[2011,12,14]],"date-time":"2011-12-14T04:25:01Z","timestamp":1323836701000},"page":"517-521","source":"Crossref","is-referenced-by-count":32,"title":["Oral tongue squamous cell carcinoma (OTSCC): alcohol and tobacco consumption versus non-consumption. A study in a Portuguese population"],"prefix":"10.1590","volume":"22","author":[{"given":"Rui","family":"Albuquerque","sequence":"first","affiliation":[{"name":"University of Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"L\u00f3pez-L\u00f3pez","sequence":"additional","affiliation":[{"name":"University of Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Mar\u00ed-Roig","sequence":"additional","affiliation":[{"name":"University of Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enric","family":"Jan\u00e9-Salas","sequence":"additional","affiliation":[{"name":"University of Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Rosell\u00f3-Llabr\u00e9s","sequence":"additional","affiliation":[{"name":"University of Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge Rosa","family":"Santos","sequence":"additional","affiliation":[{"name":"Instituto Portugues de Oncologia de Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/hed.20664","article-title":"Squamous cell carcinoma of the head and neck in never smoker-never drinkers: a descriptive epidemiologic study","volume":"30","author":"Dahlstrom KR","year":"2008","journal-title":"Head Neck","ISSN":"https:\/\/id.crossref.org\/issn\/1043-3074","issn-type":"print"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.joms.2004.03.010","article-title":"Tobacco smoking history and presentation of oral squamous cell carcinoma","volume":"62","author":"Schmidt BL","year":"2004","journal-title":"J Oral Maxillofac Surg","ISSN":"https:\/\/id.crossref.org\/issn\/0278-2391","issn-type":"print"},{"key":"ref3","first-page":"299","article-title":"Tobacco consumption among young adults in the two French departments of Savoie in 2008","volume":"57","author":"Slama K","year":"2009","journal-title":"Rev Epidemiol Sante Publique","ISSN":"https:\/\/id.crossref.org\/issn\/0398-7620","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1590\/S0103-64402003000100004","article-title":"Clinical-pathological parameters in squamous cell carcinoma of the tongue","volume":"14","author":"Dantas DD","year":"2003","journal-title":"Braz Dent J","ISSN":"https:\/\/id.crossref.org\/issn\/0103-6440","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/00020840-200304000-00002","article-title":"Current theories for the development of nonsmoking and nondrinking laryngeal carcinoma","volume":"11","author":"Wight R","year":"2003","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.otohns.2004.02.035","article-title":"Habitual risk factors for head and neck cancer","volume":"131","author":"Goldenberg D","year":"2004","journal-title":"Otolaryngol Head Neck Surg","ISSN":"https:\/\/id.crossref.org\/issn\/0194-5998","issn-type":"print"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1053\/j.seminoncol.2004.09.013","article-title":"Descriptive epidemiology and risk factors for head and neck cancer","volume":"31","author":"Sturgis EM","year":"2004","journal-title":"Semin Oncol","ISSN":"https:\/\/id.crossref.org\/issn\/0093-7754","issn-type":"print"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1002\/cncr.20998","article-title":"Tongue and tonsilcarcinoma, increasing trends in the US population ages20-44 years","volume":"103","author":"Shiboski CH","year":"2005","journal-title":"Cancer","ISSN":"https:\/\/id.crossref.org\/issn\/0008-543X","issn-type":"print"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S1368-8375(00)00135-4","article-title":"Risk factors for squamous cell carcinoma of the oral cavity in young people - 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