{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:28:23Z","timestamp":1759541303588},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>This aim of this study was to evaluate the physicochemical and biological properties of novel experimental cements (Hybrid, Paste and Resin) based on synergistic combinations of existing materials, including pH, diametral tensile strength (DTS) and cytotoxicity comparing them with mineral trioxide aggregate (MTA - Angelus\u00ae) and a glass ionomer cement (GIC) developed at our laboratory. For the physicochemical and biological tests, specimens with standard dimensions were produced. pH measurements were performed with digital pH meter at the following time intervals: 3, 24, 48 and 72 h. For the DTS test, cylindrical specimens were subjected to compressive load until fracture. The MTT assay was performed for cytotoxicity evaluation. Data were analyzed by ANOVA and Tukey's test (\u03b1=0.05). Paste group showed pH values similar to MTA, and Hybrid group presented pH values similar to GIC (p&gt;0.05). The tested materials showed pH values ranging from alkaline to near neutrality at the evaluated times. MTA and GIC showed similar DTS values. The lowest and highest DTS values were seen in the Paste and Resin groups, respectively (p&lt;0.05). Cell viability for MTA and experimental Hybrid, Paste and Resin groups was 49%, 93%, 90% and 86%, respectively, when compared with the control group. The photo-cured experimental resin cement showed similar or superior performance compared with the current commercial or other tested experimental materials.<\/jats:p>","DOI":"10.1590\/s0103-64402012000400006","type":"journal-article","created":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T09:41:33Z","timestamp":1354354893000},"page":"344-350","source":"Crossref","is-referenced-by-count":11,"title":["Novel experimental cements for use on the dentin-pulp complex"],"prefix":"10.1590","volume":"23","author":[{"given":"Raquel Ven\u00e2ncio Fernandes","family":"Dantas","sequence":"first","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus Cristian Muniz","family":"Conde","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo Ramalho","family":"Sarmento","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesar Henrique","family":"Zanchi","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra Beatriz Chaves","family":"Tarquinio","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabr\u00edcio Aulo","family":"Ogliari","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1vio Fernando","family":"Demarco","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Pathway of the Pulp","first-page":"822","volume-title":"Pediatric endodontics: endodontic treatment for the primary and young permanent dentition","author":"Camp J","year":"2006","edition":"9"},{"key":"ref2","first-page":"1","article-title":"Dentistry's friend: calcium hydroxide","volume":"22","author":"Stanley HR","year":"1997","journal-title":"Oper Dent","ISSN":"http:\/\/id.crossref.org\/issn\/0361-7734","issn-type":"print"},{"key":"ref3","first-page":"211","article-title":"Pulp response and cytotoxicity evaluation of 2 dentin bonding agents","volume":"32","author":"Demarco FF","year":"2001","journal-title":"Quintessence Int","ISSN":"http:\/\/id.crossref.org\/issn\/0033-6572","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"132","DOI":"10.14219\/jada.archive.1967.0193","article-title":"Pulp reactions to anterior restorative materials","volume":"75","author":"Stanley HR","year":"1967","journal-title":"J Am Dent Assoc","ISSN":"http:\/\/id.crossref.org\/issn\/0002-8177","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"448","DOI":"10.2341\/10-321-L","article-title":"Histologic response and tenascin and fibronectin expression after pulp capping in pig primary teeth with mineral trioxide aggregate or calcium hydroxide","volume":"36","author":"Leites A","year":"2011","journal-title":"Oper Dent","ISSN":"http:\/\/id.crossref.org\/issn\/0361-7734","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1046\/j.1365-2591.2003.00652.x","article-title":"Mineral trioxide aggregate (MTA) and calcium hydroxide as pulp-capping agents in human teeth: a preliminary report","volume":"36","author":"Aeinehchi M","year":"2003","journal-title":"Int Endod J","ISSN":"http:\/\/id.crossref.org\/issn\/0143-2885","issn-type":"print"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.archoralbio.2004.10.005","article-title":"Effects of TGF-beta s on the growth, collagen synthesis and collagen lattice contraction of human dental pulp fibroblasts in vitro","volume":"50","author":"Chan CP","year":"2005","journal-title":"Arch Oral Biol","ISSN":"http:\/\/id.crossref.org\/issn\/0003-9969","issn-type":"print"},{"key":"ref8","first-page":"82","article-title":"Buonocore Memorial Lecture","volume":"19","author":"Mount GJ","year":"1994","journal-title":"Glass-ionomer cements: past, present and future. 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