{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T01:35:00Z","timestamp":1793064900102,"version":"4.5.0"},"reference-count":17,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>South American blastomycosis, paracoccidioidomycosis (Pb mycosis) or Lutz disease is an endemically fungal infection in Latin America. It is caused by the dimorphic fungus Paracoccidioides brasiliensis and may cause oral mucosal lesions. The incidence of Pb mycosis oral lesions was evaluated in patients assisted at a Brazilian Dental School's Specialized Oral Diagnosis Service with special focus on the different clinical forms of these lesions, its location, patients' occupation, deleterious habits, and diagnosis methodology. Students' and professionals' initial diagnoses were compared with the definitive diagnosis. Lesions were detected 31 cases (18 patients). The results show that 88.8% of the patients were male with a mean age of 50 years and 39% work(ed) with activities related to agriculture. As much as 88.9% were smokers and 72.2% were alcohol users. Exfoliative cytology was performed in 66.6% of the patients. Oral mucosa (30%), gingiva (16.6%) and lips 16.6% were the most common sites of Pb mycosis oral lesions. Comparing the initial with the definitive diagnosis made by the professionals their accuracy was 33% (6 out of 18 patients). Students' diagnosis was more accurate demonstrating 72.5% of initial correct diagnosis (13 out of 18). Statistical analysis by ANOVA (\u03b1=0.05, SPSS WIN) demonstrated a significant difference between the diagnosis of Pb mycosis made by students and professionals when considering initial diagnosis and final diagnosis (after histopathological analysis) (p=0.25). Incisional biopsy and exfoliate cytology are efficient for an early diagnosis of this disease in mouth. Students' training in diagnosis of oral pathologies to recognize lesions is urgent to improve public health.<\/jats:p>","DOI":"10.1590\/s0103-64402012000600021","type":"journal-article","created":{"date-parts":[[2013,1,19]],"date-time":"2013-01-19T10:10:25Z","timestamp":1358590225000},"page":"753-757","source":"Crossref","is-referenced-by-count":21,"title":["A retrospective study of oral manifestations in patients with paracoccidioidomycosis"],"prefix":"10.1590","volume":"23","author":[{"given":"Marcelo Rodrigues","family":"Azenha","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubens","family":"Caliento","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Guilherme","family":"Brentegani","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzie Aparecida de","family":"Lacerda","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","first-page":"39","article-title":"Sequelae lesions in the larynxes of patients with paracoccidioidomycosis","volume":"77","author":"Lopes Neto JM","year":"2011","journal-title":"Braz J Otorhinolaryngol"},{"key":"ref2","first-page":"454","article-title":"Clinical-radiological dissociation in lung manifestations of paracoccidioidomycosis","volume":"4","author":"Gomes E","year":"2008","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref3","series-title":"Oral and maxillofacial pathology","author":"Neville BW","year":"2009"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"159","DOI":"10.4269\/ajtmh.2008.79.159","article-title":"Co-existence of integumentary lesions and lung x-ray abnormalities in patients with paracoccidioidomycosis (PCM)","volume":"79","author":"Restrepo A","year":"2008","journal-title":"Am J Trop Med Hyg","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9637","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s11046-007-9047-2","article-title":"Neoplasia and paracoccidioidomycosis","volume":"165","author":"Shikanai-Yasuda MA","year":"2008","journal-title":"Mycopathol"},{"key":"ref6","first-page":"91","article-title":"Paracoccidioidomycosis: report of a case treated with fluconazole","volume":"3","author":"Caballero SS","year":"1998","journal-title":"Med Oral"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1590\/S0037-86822005000300005","article-title":"Clinical-epidemiologic profile of paracoccidioidomycosis at the Stomatology Department of S\u00e3o Lucas Hospital, Pontifical Catholic University of Rio Grande do Sul","volume":"38","author":"Verli FD","year":"2005","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref8","first-page":"23","article-title":"Oral clinical manifestations of paracoccidioidomycosis","volume":"35","author":"Vieira EMM","year":"2006","journal-title":"Rev Patol Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0301-0406","issn-type":"print"},{"key":"ref9","first-page":"295","article-title":"Association between paracoccidioidomycosis and tuberculosis: reality and misdiagnosis","volume":"33","author":"Quagliato-J\u00fanior R","year":"2000","journal-title":"Braz J Pneumol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1128\/CMR.6.2.89","article-title":"Paracoccidioidomycosis: an update","volume":"6","author":"Brummer E","year":"1993","journal-title":"Clin Microbiol Rev","ISSN":"https:\/\/id.crossref.org\/issn\/0893-8512","issn-type":"print"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1067\/moe.2002.129179","article-title":"Paracoccidioidomycosis: Report of 2 cases mimicking squamous cell carcinoma","volume":"94","author":"Meneses-Garcia A","year":"2002","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod","ISSN":"https:\/\/id.crossref.org\/issn\/1079-2104","issn-type":"print"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/MAJ.0b013e3180a6f1e5","article-title":"Paracoccidioidomycosis (South American blastomycosis) of the larynx mimicking carcinoma","volume":"335","author":"Garcia I","year":"2008","journal-title":"Am J Med Sci","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9629","issn-type":"print"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1093\/ajcp\/25.8_ts.0975","article-title":"A stain for fungi in tissue sections and smears: using Gomori's methenamine - silver nitrate technique","volume":"25","author":"Grocott RG","year":"1955","journal-title":"Am J Clin Pathol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9173","issn-type":"print"},{"key":"ref14","first-page":"427","article-title":"Evaluation of cytopathologic exam for diagnosis of oral chronic paracoccidioidomycosis","volume":"36","author":"Ara\u00fajo MS","year":"2003","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1600-0714.1994.tb00262.x","article-title":"Paracoccidioidomycosis manifesting as oral lesions: clinical, cytological investigation","volume":"23","author":"Sposto MR","year":"1994","journal-title":"J Oral Pathol Med","ISSN":"https:\/\/id.crossref.org\/issn\/0904-2512","issn-type":"print"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1128\/JCM.38.9.3478-3480.2000","article-title":"PCR for diagnosis of paracoccidioidomycosis","volume":"38","author":"Gomes GM","year":"2000","journal-title":"J Clin Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1056\/NEJM199401273300407","article-title":"Oral azole drugs as systemic antifungal therapy","volume":"330","author":"Como JA","year":"1994","journal-title":"N Engl J Med","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"}],"container-title":["Brazilian Dental Journal"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/bdj\/v23n6\/v23n06a21.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T19:02:27Z","timestamp":1595271747000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0103-64402012000600021&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012]]}},"alternative-id":["S0103-64402012000600021"],"URL":"https:\/\/doi.org\/10.1590\/s0103-64402012000600021","relation":{},"ISSN":["0103-6440"],"issn-type":[{"value":"0103-6440","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}