{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T16:55:26Z","timestamp":1773766526168,"version":"3.50.1"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An. Bras. Dermatol."],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p>FUNDAMENTO: As doen\u00e7as dermatol\u00f3gicas imunologicamente mediadas comp\u00f5em diversas patologias que apresentam formas variadas de manifesta\u00e7\u00e3o no organismo. OBJETIVO: Foi proposi\u00e7\u00e3o desta pesquisa, estabelecer a preval\u00eancia das principais doen\u00e7as dermatol\u00f3gicas imunologicamente mediadas que apresentam manifesta\u00e7\u00e3o oral. M\u00c9TODOS: Foram avaliados laudos histopatol\u00f3gicos de 10.292 casos arquivados no Servi\u00e7o de Anatomia Patol\u00f3gica da Disciplina de Patologia Oral da Universidade Federal do Rio Grande do Norte, no per\u00edodo de 1988 a 2009. Dos casos diagnosticados como algum tipo de doen\u00e7a em estudo, coletaram-se dados cl\u00ednicos como sexo, idade, ra\u00e7a, s\u00edtio anat\u00f4mico e sintomatologia das doen\u00e7as. RESULTADOS: Do total de casos registrados, no servi\u00e7o supracitado, 82 (0,8%) corresponderam a doen\u00e7as dermato l\u00f3gicas imunologicamente mediadas com manifesta\u00e7\u00e3o na cavidade oral. As doen\u00e7as encontradas neste estudo foram: l\u00edquen plano oral, p\u00eanfigo vulgar e penfigoide benigno das membranas mucosas, sendo o l\u00edquen plano oral a les\u00e3o mais prevalente, representando 68,05% dos casos analisados, dos quais 64,3% apresentavam-se em mu lheres, sendo a mucosa jugal o s\u00edtio anat\u00f4mico mais acometido (46,8%). CONCLUS\u00c3O: A ocorr\u00eancia de doen\u00e7as dermatol\u00f3gicas imunologicamente mediadas que apresentam manifesta\u00e7\u00e3o oral ainda \u00e9 um fato incomum, semelhante ao observado na maioria das regi\u00f5es mundiais. No entanto, a busca pelo diagn\u00f3stico precoce \u00e9 um requisito essencial para a condu\u00e7\u00e3o do tratamento dessas doen\u00e7as, tendo em vista o poss\u00edvel comprometimento sist\u00eamico do organismo nos pacientes.<\/jats:p>","DOI":"10.1590\/s0365-05962011000500007","type":"journal-article","created":{"date-parts":[[2011,12,3]],"date-time":"2011-12-03T06:54:12Z","timestamp":1322895252000},"page":"905-909","source":"Crossref","is-referenced-by-count":13,"title":["Estudo epidemiol\u00f3gico das doen\u00e7as dermatol\u00f3gicas imunologicamente mediadas na cavidade oral"],"prefix":"10.1590","volume":"86","author":[{"given":"Cyntia Helena Pereira de","family":"Carvalho","sequence":"first","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruna Rafaela Martins dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila de Castro","family":"Vieira","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emeline das Neves de Ara\u00fajo","family":"Lima","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Paulo de Andrade","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roseana de Almeida","family":"Freitas","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1601-0825.2005.01140.x","article-title":"Mucosal disease series number III: mucous membrane pemphigoid","volume":"11","author":"Bagan JM","year":"2005","journal-title":"Oral Dis","ISSN":"https:\/\/id.crossref.org\/issn\/1354-523X","issn-type":"print"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"395","DOI":"10.4321\/S1138-123X2004000400003","article-title":"L\u00edquen plano oral: Naturaleza, aspectos cl\u00ednicos y tratamiento","volume":"9","author":"Bermejo-Fenoll A","year":"2004","journal-title":"RCOE","ISSN":"https:\/\/id.crossref.org\/issn\/1136-4319","issn-type":"print"},{"key":"ref3","first-page":"8","article-title":"P\u00eanfigo Vulgar e Penfig\u00f3ide Benigno de Mucosa: Considera\u00e7\u00f5es gerais e relato de casos","volume":"2","author":"Cazal CM","year":"2003","journal-title":"Rev Bras Patol Oral"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.bjoms.2007.07.199","article-title":"Oral mucosal disease: lichen planus","volume":"46","author":"Scully C","year":"2008","journal-title":"Br J Oral Maxillofac Surg","ISSN":"https:\/\/id.crossref.org\/issn\/0266-4356","issn-type":"print"},{"key":"ref5","first-page":"145","article-title":"P\u00eanfigo: Revis\u00e3o da literatura e relato de um caso","volume":"3","author":"Farias ABL","year":"2004","journal-title":"Rev Bras Patol Oral"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1590\/S0365-05962010000200004","article-title":"Avalia\u00e7\u00e3o cl\u00ednica das les\u00f5es orais associadas a doen\u00e7as dermatol\u00f3gicas","volume":"85","author":"Gon\u00e7alves LM","year":"2010","journal-title":"An Bras Dermatol","ISSN":"https:\/\/id.crossref.org\/issn\/0365-0596","issn-type":"print"},{"key":"ref7","first-page":"157","article-title":"Manifestaciones mucocut\u00e1neas del liquen plano: Revisi\u00f3n bibliogr\u00e1fica","volume":"39","author":"Rodriguez Calzadilla OL","year":"2002","journal-title":"Rev Cubana Estomatol","ISSN":"https:\/\/id.crossref.org\/issn\/0034-7507","issn-type":"print"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1902\/jop.2008.070231","article-title":"Diagnostic pathways and clinical significance of desquamative gingivitis","volume":"79","author":"Lo Russo L","year":"2008","journal-title":"J Periodontol","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3492","issn-type":"print"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1601-0825.2005.01142.x","article-title":"Oral lichen planus: clinical features and management","volume":"11","author":"Eisen D","year":"2005","journal-title":"Oral Dis","ISSN":"https:\/\/id.crossref.org\/issn\/1354-523X","issn-type":"print"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1590\/S0034-72992008000200021","article-title":"L\u00edquen plano bucal: considera\u00e7\u00f5es cl\u00ednicas e histopatol\u00f3gicas","volume":"74","author":"Sousa FACG","year":"2008","journal-title":"Rev. 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