{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:39:46Z","timestamp":1768437586595,"version":"3.49.0"},"reference-count":10,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An. Bras. Dermatol."],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>Phyma is the last stage of rosacea and is due to chronic inflammation and edema. It can affect nose (rhinophyma), chin (gnatophyma), forehead (metophyma), ears (otophyma) and eyelids (blepharophyma). Rhinophyma is the most frequent location and there are few reports about gnatophyma. We report the case of a female patient, 41 years old, who had an infiltrated, erythematous, edematous plaque around the chin and lower lip for two years. Histopathology showed perivascular lymphocytic infiltrate, hypertrophied follicles and sebaceous glands, dilated vessels and fibrosis. She was treated with oral tetracycline, oral ivermectin and metronidazole cream with a satisfactory response. The clinical, histopathological and therapeutic response correlation confirmed the diagnosis of gnatophyma, a rare variant of phyma.<\/jats:p>","DOI":"10.1590\/s0365-05962012000600014","type":"journal-article","created":{"date-parts":[[2012,11,28]],"date-time":"2012-11-28T07:56:04Z","timestamp":1354089364000},"page":"903-905","source":"Crossref","is-referenced-by-count":12,"title":["Gnatophyma: a rare form of rosacea"],"prefix":"10.1590","volume":"87","author":[{"given":"Ana Carolina Lisboa de","family":"Macedo","sequence":"first","affiliation":[{"name":"University of Santo Amaro,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Dias Pacheco","family":"Sakai","sequence":"additional","affiliation":[{"name":"University of Santo Amaro,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossana Cantanhede Farias de","family":"Vasconcelos","sequence":"additional","affiliation":[{"name":"University of Santo Amaro,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artur Antonio","family":"Duarte","sequence":"additional","affiliation":[{"name":"University of Santo Amaro,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.jaad.2004.03.030","article-title":"Rosacea: I. 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