{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T03:12:32Z","timestamp":1789269152189,"version":"build-2803163510"},"reference-count":20,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"abstract":"<jats:p>ABSTRACT Myiasis, a condition stemming from the parasitic infestation of Diptera fly larvae, constitutes a complication for cancer patients, particularly those with malignant skin wounds. The factors that contribute to myiasis include old age, inadequate hygiene, poor living conditions, vascular disease, and diabetes. Cases of myiasis in neoplastic wounds in the head and neck region are rare and guidelines or recommendations regarding the best treatment approach remain lacking. Herein, we describe a case of myiasis that developed into an extensive squamous cell carcinoma of the lip in an older male adult due to the delay in oncological treatment stemming from the COVID-19 pandemic. Patients with oral squamous cell carcinoma, especially those residing in rural areas, face a notable risk of developing oral myiasis. Therefore, it is imperative that patients and caregivers adopt strict preventive measures to avoid fly infestations in wounds. Maintaining optimal hygiene (including meticulous cleaning with antiseptic solutions before daily dressing changes) is essential to prevent myiasis. Adequate wound coverage is crucial, especially during warmer seasons.<\/jats:p>","DOI":"10.1590\/s1678-9946202567006","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T11:32:04Z","timestamp":1740051124000},"source":"Crossref","is-referenced-by-count":4,"title":["Myiasis infestation in advanced lip squamous cell carcinoma due to COVID-19 pandemic-related treatment delays"],"prefix":"10.1590","volume":"67","author":[{"given":"Lucas Emanuel Macena da","family":"Silva","sequence":"first","affiliation":[{"name":"Centro Universit\u00e1rio de Patos,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lia Vit\u00f3ria de Ara\u00fajo","family":"Lopes","sequence":"additional","affiliation":[{"name":"Universidade Estadual da Para\u00edba,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego de Sena Costa de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Federal do Oeste da Bahia,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Eduardo Marinho","family":"Vieira","sequence":"additional","affiliation":[{"name":"Universidade Estadual da Para\u00edba,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hianne Cristinne de Morais","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio de Patos,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Augusto Benevenuto de","family":"Andrade","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio de Janeiro,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Carvalho de","family":"Souza","sequence":"additional","affiliation":[{"name":"Universidade Federal do Oeste da Bahia,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0679-8485","authenticated-orcid":false,"given":"John Lennon Silva","family":"Cunha","sequence":"additional","affiliation":[{"name":"Universidade Federal do Oeste da Bahia,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luan \u00c9verton Galdino","family":"Barnab\u00e9","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio de Patos,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"key":"ref1","article-title":"Epidemiology, risk factors, and prevention of head and neck squamous cell carcinoma","volume":"11","author":"Barsouk A","year":"2023","journal-title":"Med Sci (Basel)"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.1016\/j.bjorl.2021.11.003","article-title":"Nutritional and immunological parameters as prognostic factors in patients with advanced oral cancer","volume":"88","author":"Trevisani LF","year":"2022","journal-title":"Braz J Otorhinolaryngol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"E19","DOI":"10.1177\/014556131709600704","article-title":"Myiasis in patients with head and neck cancer: Seldom described but commonly seen","volume":"96","author":"Girardi FM","year":"2017","journal-title":"Ear Nose Throat J"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1227\/00006123-198603000-00021","article-title":"Myiatic scalp and skull infection with diptera Sarcophaga: case report","volume":"18","author":"Arbit E","year":"1986","journal-title":"Neurosurgery"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/j.1365-2133.1993.tb03189.x","article-title":"Opportunistic cutaneous myiasis following radiotherapy for squamous cell carcinoma of the left temple","volume":"129","author":"Phillips WG","year":"1993","journal-title":"Br J Dermatol"},{"key":"ref6","first-page":"1","article-title":"Miasis facial asociada con carcinoma espinocelular en estado terminal","volume":"42","author":"Maciel-Santos ME","year":"2005","journal-title":"Rev Cubana Estomatol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.jaad.2005.07.012","article-title":"Myiasis in a giant squamous cell carcinoma","volume":"54","author":"Hawayek LH","year":"2006","journal-title":"J Am Acad Dermatol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0001-7310(06)73346-4","article-title":"Miasis cut\u00e1neas sobre lesiones tumorales: presentaci\u00f3n de tres casos","volume":"97","author":"Rubio C","year":"2006","journal-title":"Actas Dermosifiliogr"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2334\/josnusd.50.103","article-title":"Oral and maxillofacial myiasis associated with epidermoid carcinoma: a case report","volume":"50","author":"Carvalho RW","year":"2008","journal-title":"J Oral Sci"},{"key":"ref10","first-page":"E9","article-title":"Extensive myiasis infestation over a squamous cell carcinoma in the face: case report","volume":"13","author":"Gabriel JG","year":"2008","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jaad.2008.09.065","article-title":"Massive oculofacial myiasis infestation with Lucilia sericata","volume":"61","author":"Cavusoglu T","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"ref12","first-page":"64","article-title":"Cutaneous manifestation of myiasis in malignant wounds of the head and neck","volume":"19","author":"Sesterhenn AM","year":"2009","journal-title":"Eur J Dermatol"},{"key":"ref13","first-page":"63","article-title":"Orbital myiasis complicating squamous cell carcinoma of eyelid","volume":"16","author":"Yeung JC","year":"2010","journal-title":"Hong Kong Med J"},{"key":"ref14","article-title":"Myiasis infestation in advanced oral squamous cell carcinoma","author":"Pessoa L","year":"2011","journal-title":"BMJ Case 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