{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:29:36Z","timestamp":1773278976178,"version":"3.50.1"},"reference-count":33,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Einstein (S\u00e3o Paulo)"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:p>ABSTRACT Premature ejaculation is the most frequent male sexual dysfunction, estimated to affect 20 to 30% of men at some time in their life. A Pubmed search from the year 2000 to the present was performed to retrieve publications related to management or treatment of premature ejaculation. Behavioral techniques have been the mainstay of premature ejaculation management for many years, although evidence of their short-term efficacy is limited. Topical therapies for premature ejaculation act by desensitizing the penis and do not alter the sensation of ejaculation. Selective serotonin reuptake inhibitors (SSRIs), commonly used in the treatment of depression, are often used to treat premature ejaculation, based on the observation that delayed ejaculation is a frequent side effect of this drug class. Dapoxetine is a short-acting SSRI formulated to treat premature ejaculation, and results seem very promising.<\/jats:p>","DOI":"10.1590\/s1679-45082011rb1929","type":"journal-article","created":{"date-parts":[[2015,8,29]],"date-time":"2015-08-29T23:06:29Z","timestamp":1440889589000},"page":"545-549","source":"Crossref","is-referenced-by-count":1,"title":["Premature ejaculation: is there an efficient therapy?"],"prefix":"10.1590","volume":"9","author":[{"given":"F\u00e1bio Barros de","family":"Francischi","sequence":"first","affiliation":[{"name":"Faculdade de Medicina de S\u00e3o Jos\u00e9 do Rio Preto \u2013 FAMERP,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Cernach","family":"Ayres","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina de S\u00e3o Jos\u00e9 do Rio Preto \u2013 FAMERP,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Eidi","family":"Itao","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina de S\u00e3o Jos\u00e9 do Rio Preto \u2013 FAMERP,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Cesar Fava","family":"Spessoto","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina de S\u00e3o Jos\u00e9 do Rio Preto \u2013 FAMERP,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Germano Ferraz del","family":"Arruda","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina de S\u00e3o Jos\u00e9 do Rio Preto \u2013 FAMERP,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Nestor","family":"Facio Junior","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina de S\u00e3o Jos\u00e9 do Rio Preto \u2013 FAMERP,  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