{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T17:54:33Z","timestamp":1714672473105},"reference-count":21,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Einstein (S\u00e3o Paulo)"],"abstract":"<jats:p>We aimed to identify the late effects of radiation exposure in pediatric cancer survivors. An integrated literature review was performed in the databases MEDLINE and LILACS and SciELO. Included were articles in Portuguese and English, published over the past 10 years, using the following keywords: \u201cneoplasias\/neoplasms\u201d AND \u201cradioterapia\/radiotherapy\u201d AND \u201cradia\u00e7\u00e3o\/radiation\u201d. After analysis, 14 articles - published in nine well-known journals - met the inclusion criteria. The publications were divided into two categories: \u201cLate endocrine effects\u201d and \u201cLate non-endocrine effects\u201d. Considering the increased survival rates in children who had cancer, the impact of late effects of exposure to radiation during radiological examinations for diagnosis and treatment was analyzed. Childhood cancer survivors were exposed to several late effects and should be early and regularly followed up, even when exposed to low radiation doses.<\/jats:p>","DOI":"10.1590\/s1679-45082015rw3102","type":"journal-article","created":{"date-parts":[[2015,8,19]],"date-time":"2015-08-19T22:50:57Z","timestamp":1440024657000},"page":"71-76","source":"Crossref","is-referenced-by-count":6,"title":["Impact of late radiation effects on cancer survivor children: an integrative review"],"prefix":"10.1590","volume":"14","author":[{"given":"Cibeli Fernandes","family":"Coura","sequence":"first","affiliation":[{"name":"Hospital Israelita Albert Einstein,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia Cl\u00e1udia","family":"Modesto","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2015,8,21]]},"reference":[{"key":"ref1","series-title":"Estimativa 2012 2014: Incid\u00eancia de C\u00e2ncer no Brasil","year":"2014"},{"issue":"9","key":"ref2","first-page":"819","article-title":"Evaluation of the main late endocrine effects in children and adolescents after treatment of malignancies","volume":"54","author":"Kupeman H","year":"2010","journal-title":"Arq Bras Endocrinol Metabol"},{"issue":"6","key":"ref3","first-page":"359","article-title":"Thyroid disorders associated with external radiation in children and adolescents","volume":"55","author":"Bonato CC","year":"2011","journal-title":"Arq Bras Endocrinol Metabol"},{"issue":"5","key":"ref4","first-page":"825","article-title":"Endocrine sequelae after radiotherapy in childhood and adolescence","volume":"49","author":"Couto-Silva AC","year":"2005","journal-title":"Arq Bras Endocrinol Metabol"},{"issue":"4","key":"ref5","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1590\/S0104-07072008000400018","article-title":"Revis\u00e3o integrativa: m\u00e9todo de pesquisa para a incorpora\u00e7\u00e3o de evid\u00eancias na sa\u00fade e na enfermagem","volume":"17","author":"Mendes KD","year":"2008","journal-title":"Texto Contexto Enferm"},{"issue":"6","key":"ref6","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1667\/RR1903.1","article-title":"Long-term effects of radiation exposure among adult survivors of childhood cancer: results from the childhood cancer survivor study","volume":"174","author":"Armstrong GT","year":"2010","journal-title":"Radiat Res"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/cncr.25376","article-title":"Prognostic factors and long-term outcomes of childhood nasopharyngeal carcinoma","volume":"117","author":"Cheuk DK","year":"2011","journal-title":"Cancer"},{"issue":"6","key":"ref8","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1667\/RR2240.1","article-title":"Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study","volume":"174","author":"Bhatti P","year":"2010","journal-title":"Radiat Res"},{"issue":"2","key":"ref9","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/ncpendmet1051","article-title":"Radiation-induced hypopituitarism after cancer therapy: who, how and when to test","volume":"5","author":"Darzy KH","year":"2009","journal-title":"Nat Clin Pract Endocrinol Metab"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1590\/S0004-27302009000200011","article-title":"Adiposity in childhood cancer survivors: insights into obesity physiopathology","volume":"53","author":"Silviero-Miachom AA","year":"2009","journal-title":"Arq Bras Endocrinol Metabol"},{"issue":"15","key":"ref11","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1001\/archinternmed.2009.209","article-title":"Diabetes mellitus in long-term survivors of childhood cancer. 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