{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T21:17:14Z","timestamp":1722115034801},"reference-count":7,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Einstein (S\u00e3o Paulo)"],"abstract":"<jats:p>ABSTRACT A 69-year-old male patient, smoker, was diagnosed with small cell lung cancer metastatic to lung, liver and central nervous system. He received chemotherapy with carboplatin AUC 5 on day 1 and etoposide 100mg\/m2 on days 1, 2 and 3. During the first cycle, the patient presented with febrile neutropenia and abdominal distension. Chest, abdomen and pelvis computed tomography scan was performed and detected gas dissecting the wall of sigmoid colon extending to the mesosigmoid. Patient had no abdominal pain, nausea, vomiting, and on physical examination he had no peritoneal irritation, tachycardia or hemodynamic instability compatible with perforation or acute abdomen. Therefore, the radiological finding was interpreted as pneumatosis intestinalis caused by chemotherapy with etoposide. Pneumatosis resolved after continuous oxygen therapy. The second cycle was administered after a complete resolution of the clinical condition and etoposide dose was reduced by 30%. The patient experienced a remarkable evolution.<\/jats:p>","DOI":"10.1590\/s1679-45082016rc3597","type":"journal-article","created":{"date-parts":[[2016,8,13]],"date-time":"2016-08-13T13:02:09Z","timestamp":1471093329000},"page":"420-422","source":"Crossref","is-referenced-by-count":6,"title":["Pneumatosis intestinalis after etoposide-based chemotherapy in a patient with metastatic small cell lung cancer: successful conservative management of a rare condition"],"prefix":"10.1590","volume":"14","author":[{"given":"Luiza Dib Batista Bugiato","family":"Faria","sequence":"first","affiliation":[{"name":"Hospital S\u00edrio-Lib\u00e2nes,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Henrique dos","family":"Anjos","sequence":"additional","affiliation":[{"name":"Hospital S\u00edrio-Lib\u00e2nes,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo dos Santos","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Hospital S\u00edrio-Lib\u00e2nes,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor Fernando da Silva","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Hospital Bras\u00edlia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2016,8,15]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"crossref","DOI":"10.1590\/S0104-42302010000200009","article-title":"Pneumatose intestinal","volume":"56","author":"Loureiro JF","year":"2010","journal-title":"Rev Assoc Med Bras"},{"issue":"6","key":"ref2","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.2214\/AJR.06.1309","article-title":"Pneumatosis intestinalis in the adult: benign to life-threatening causes","volume":"188","author":"Ho LM","year":"2007","journal-title":"AJR Am J Roentgenol"},{"issue":"10","key":"ref3","first-page":"1747","article-title":"Pneumatosis intestinalis: a review","volume":"90","author":"Heng Y","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"ref4","series-title":"Gastrointestinal disease: pathophysiology, diagnosis and management","volume-title":"Other diseases of the colon and rectum","author":"Earnest D","year":"1989"},{"issue":"5","key":"ref5","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1590\/S0100-69912001000500013","article-title":"Pneumatosis Intestinalis","volume":"28","author":"Veloso LF","year":"2001","journal-title":"Rev Col Bras Cir"},{"issue":"14","key":"ref6","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.2169\/internalmedicine.54.4255","article-title":"A rare case of benign pneumatosis intestinalis with portal venous gas and pneumoperitoneum induced by acarbose","volume":"54","author":"Rottenstreich A","year":"2015","journal-title":"Intern Med"},{"issue":"12","key":"ref7","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1200\/JCO.2006.10.5742","article-title":"Pneumatosis coli after etoposide chemotherapy for breast cancer","volume":"25","author":"Shih IL","year":"2007","journal-title":"J Clin Oncol"}],"container-title":["Einstein (S\u00e3o Paulo)"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/eins\/v14n3\/1679-4508-eins-S1679-45082016RC3597.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T01:14:38Z","timestamp":1520298878000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1679-45082016000300420&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,15]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,9]]}},"alternative-id":["S1679-45082016000300420"],"URL":"https:\/\/doi.org\/10.1590\/s1679-45082016rc3597","relation":{},"ISSN":["2317-6385","1679-4508"],"issn-type":[{"value":"2317-6385","type":"electronic"},{"value":"1679-4508","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8,15]]}}}