{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T07:24:33Z","timestamp":1758266673681},"reference-count":28,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. bras. pneumol."],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:p>OBJETIVO: Comparar as manifesta\u00e7\u00f5es cl\u00ednicas, radiol\u00f3gicas e laboratoriais de indiv\u00edduos com tuberculose pulmonar coinfectados com HIV com aqueles sem a coinfec\u00e7\u00e3o. M\u00c9TODOS: Estudo transversal, no qual sinais e sintomas foram analisados por meio de anamnese e exame f\u00edsico em pacientes internados com tuberculose pulmonar. A baciloscopia, a cultura para Mycobacterium tuberculosis, a dosagem de hemoglobina e a contagem de c\u00e9lulas T CD4+ foram obtidas de registros dos prontu\u00e1rios, assim como os laudos das radiografias de t\u00f3rax. RESULTADOS: Foram inclu\u00eddos 50 pacientes com tuberculose pulmonar, que foram divididos em dois grupos (HIV positivo e HIV negativo; n = 25 por grupo). A m\u00e9dia de idade dos participantes foi de 38,4 \u00b1 10,5 anos, 46 (92%) eram do sexo masculino, e 27 (54%) eram caucasianos. Apresentaram expectora\u00e7\u00e3o 21 (84%) e 13 (52%) dos pacientes nos grupos HIV negativo e HIV positivo, respectivamente (p = 0,016). Achados radiol\u00f3gicos de cavita\u00e7\u00e3o estavam presentes em 10 (43%) e 2 (10%) dos pacientes nos grupos HIV negativo e HIV positivo, respectivamente (p = 0,016), ao passo que padr\u00e3o intersticial estava presente em 18 (78%) e 8 (40%) dos pacientes nesses grupos (p = 0,012). O n\u00edvel m\u00e9dio de hemoglobina foi de 11,1 \u00b1 2,9 g\/dL e 9,3 \u00b1 2,2 g\/dL nos grupos HIV negativo e HIV positivo, respectivamente (p = 0,015). CONCLUS\u00d5ES: Entre pacientes coinfectados com tuberculose e HIV desta amostra, houve menor preval\u00eancia de expectora\u00e7\u00e3o, foram menos frequentes os achados radiol\u00f3gicos de cavita\u00e7\u00e3o e de padr\u00e3o intersticial, e os n\u00edveis de hemoglobina foram mais baixos do que naqueles sem essa coinfec\u00e7\u00e3o.<\/jats:p>","DOI":"10.1590\/s1806-37132011000600010","type":"journal-article","created":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T23:46:20Z","timestamp":1326239180000},"page":"768-775","source":"Crossref","is-referenced-by-count":6,"title":["Manifesta\u00e7\u00f5es cl\u00ednicas, radiol\u00f3gicas e laboratoriais em indiv\u00edduos com tuberculose pulmonar: estudo comparativo entre indiv\u00edduos HIV positivos e HIV negativos internados em um hospital de refer\u00eancia"],"prefix":"10.1590","volume":"37","author":[{"given":"Aline","family":"Besen","sequence":"first","affiliation":[{"name":"Universidade Federal de Santa Catarina,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme J\u00f6nck","family":"Staub","sequence":"additional","affiliation":[{"name":"Universidade Federal de Santa Catarina,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosemeri Maurici da","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade do Sul de Santa Catarina,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Controle da Tuberculose: uma proposta de integra\u00e7\u00e3o ensinoservi\u00e7o","year":"2002","edition":"5"},{"issue":"3","key":"ref2","first-page":"393","article-title":"The radiographic appearance of tuberculosis in patients with the acquired immune deficiency syndrome (AIDS) and pre-AIDS","volume":"131","author":"Pitchenik AE","year":"1985","journal-title":"Am Rev Respir 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