{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T02:59:01Z","timestamp":1772852341487,"version":"3.50.1"},"reference-count":15,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. bras. pneumol."],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p>Objective: Pregnancy brings about significant changes in respiratory function, as evidenced by alterations in lung volumes and capacities, which are attributable to the mechanical impediment caused by the growing foetus. This study was undertaken in order to identify changes in respiratory function during normal pregnancy and to determine whether such changes are more pronounced in twin pregnancy than in singleton pregnancy. Methods: Respiratory function was assessed in 50 women with twin pregnancies and in 50 women with singleton pregnancies (during the third trimester in both groups), as well as in 50 non-pregnant women. We measured the following pulmonary function test parameters: FVC; FEV1; PEF rate; FEV1\/FVC ratio; FEF25-75%; and maximal voluntary ventilation. Results: All respiratory parameters except the FEV1\/FVC ratio were found to be lower in the pregnant women than in the non-pregnant women. We found no significant differences between women with twin pregnancies and those with singleton pregnancies, in terms of respiratory function. Conclusions: Despite its higher physiological demands, twin pregnancy does not appear to impair respiratory function to any greater degree than does singleton pregnancy.<\/jats:p>","DOI":"10.1590\/s1806-37132014000300007","type":"journal-article","created":{"date-parts":[[2014,7,14]],"date-time":"2014-07-14T12:40:45Z","timestamp":1405341645000},"page":"244-249","source":"Crossref","is-referenced-by-count":6,"title":["Pulmonary function in advanced uncomplicated singleton and twin pregnancy"],"prefix":"10.1590","volume":"40","author":[{"given":"Anwar Hasan","family":"Siddiqui","sequence":"first","affiliation":[{"name":"Jawaharlal Nehru Medical College, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazia","family":"Tauheed","sequence":"additional","affiliation":[{"name":"Jawaharlal Nehru Medical College, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aquil","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Jawaharlal Nehru Medical College, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehra","family":"Mohsin","sequence":"additional","affiliation":[{"name":"Jawaharlal Nehru Medical College, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Obstetrics and Gynecology","first-page":"46","volume-title":"Physiological changes during pregnancy","author":"Dutta DC","year":"1998","edition":"4th edition"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0272-5231(21)01125-4","article-title":"Respiratory physiology in pregnancy","volume":"13","author":"Elkus R","year":"1992","journal-title":"Clin Chest Med"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ccm.2010.11.001","article-title":"Respiratory physiology in pregnancy","volume":"32","author":"Hegewald MJ","year":"2001","journal-title":"Clin Chest Med"},{"key":"ref4","series-title":"Physiological changes associated with pregnancy. Update in Anaesthesia","first-page":"72","volume":"9","author":"Christopher FC","year":"1998"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00404-004-0691-1","article-title":"Lung function and breathing regulation parameters during pregnancy","volume":"272","author":"Kolarzyk E","year":"2005","journal-title":"Arch Gynecol Obstet"},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1164\/ajrccm\/144.4.837","article-title":"Ventilatory drive and respiratory muscle function in pregnancy","volume":"144","author":"Contreras G","year":"1991","journal-title":"Am Rev Respir Dis"},{"issue":"3","key":"ref7","first-page":"352","article-title":"A longitudinal study of antenatal changes in lung function tests and importance of postpartum exercises in their recovery","volume":"47","author":"Phatak MS","year":"2003","journal-title":"Indian J Physiol Pharmacol"},{"issue":"9","key":"ref8","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1093\/humrep\/deg369","article-title":"Monozygotic twinning following assisted conception: an analysis of 81 consecutive cases","volume":"18","author":"Alikani M","year":"2003","journal-title":"Hum Reprod"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.iac.2005.10.004","article-title":"Respiratory physiologic changes in pregnancy","volume":"26","author":"Wise RA","year":"2006","journal-title":"Immunol Allergy Clin North Am"},{"key":"ref10","series-title":"Current obstetrics & gynecologic: diagnosis and treatment","first-page":"159","volume-title":"Maternal physiology during pregnancy","author":"DeCherney AH","year":"2003","edition":"9th edition"},{"issue":"2","key":"ref11","first-page":"130","article-title":"Effect of anaemia on respiratory and metabolic parameters during third trimester of pregnancy","volume":"31","author":"Singhal U","year":"1987","journal-title":"Indian J Physiol Pharmacol"},{"issue":"2","key":"ref12","first-page":"135","article-title":"PEFR in pregnancy: a longitudinal study","volume":"39","author":"Puranik BM","year":"1995","journal-title":"Ind J Physiol Pharmacol"},{"issue":"2","key":"ref13","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ccm.2004.01.010","article-title":"Pulmonary complications of pregnancy","volume":"25","author":"Pereira A","year":"2004","journal-title":"Clin Chest Med"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"R1369","DOI":"10.1152\/ajpregu.00862.2004","article-title":"Effects of human pregnancy on the ventilatory chemoreflex response to carbon dioxide","volume":"288","author":"Jensen D","year":"2005","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1677\/joe.0.1420261","article-title":"The regulation of plasma relaxin levels during human pregnancy","volume":"142","author":"Johnson MR","year":"1994","journal-title":"J Endocrinol"}],"container-title":["Jornal Brasileiro de Pneumologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/jbpneu\/v40n3\/1806-3713-jbpneu-40-03-00244.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:56:26Z","timestamp":1649638586000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1806-37132014000300244&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["S1806-37132014000300244"],"URL":"https:\/\/doi.org\/10.1590\/s1806-37132014000300007","relation":{},"ISSN":["1806-3713"],"issn-type":[{"value":"1806-3713","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6]]}}}