{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:35:47Z","timestamp":1791358547656,"version":"4.3.1"},"reference-count":40,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. bras. pneumol."],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:p>Objective: To investigate the applicability of ultrasound imaging of the diaphragm in interstitial lung disease (ILD). Methods: Using ultrasound, we compared ILD patients and healthy volunteers (controls) in terms of diaphragmatic mobility during quiet and deep breathing; diaphragm thickness at functional residual capacity (FRC) and at total lung capacity (TLC); and the thickening fraction (TF, proportional diaphragm thickening from FRC to TLC). We also evaluated correlations between diaphragmatic dysfunction and lung function variables. Results: Between the ILD patients (n = 40) and the controls (n = 16), mean diaphragmatic mobility was comparable during quiet breathing, although it was significantly lower in the patients during deep breathing (4.5 \u00b1 1.7 cm vs. 7.6 \u00b1 1.4 cm; p &lt; 0.01). The patients showed greater diaphragm thickness at FRC (p = 0.05), although, due to lower diaphragm thickness at TLC, they also showed a lower TF (p &lt; 0.01). The FVC as a percentage of the predicted value (FVC%) correlated with diaphragmatic mobility (r = 0.73; p &lt; 0.01), and an FVC% cut-off value of &lt; 60% presented high sensitivity (92%) and specificity (81%) for indentifying decreased diaphragmatic mobility. Conclusions: Using ultrasound, we were able to show that diaphragmatic mobility and the TF were lower in ILD patients than in healthy controls, despite the greater diaphragm thickness at FRC in the former. Diaphragmatic mobility correlated with ILD functional severity, and an FVC% cut-off value of &lt; 60% was found to be highly accurate for indentifying diaphragmatic dysfunction on ultrasound.<\/jats:p>","DOI":"10.1590\/s1806-37562015000000266","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T23:29:04Z","timestamp":1462404544000},"page":"88-94","source":"Crossref","is-referenced-by-count":62,"title":["Identifying decreased diaphragmatic mobility and diaphragm thickening in interstitial lung disease: the utility of ultrasound imaging"],"prefix":"10.1590","volume":"42","author":[{"given":"Pauliane Vieira","family":"Santana","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brasil; A.C. Camargo Cancer Center, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Prina","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 Luis Pereira","family":"Albuquerque","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Roberto Ribeiro","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Caruso","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brasil; A.C. 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