{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T05:30:54Z","timestamp":1781242254573,"version":"3.54.1"},"reference-count":38,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. bras. pneumol."],"abstract":"<jats:p>ABSTRACT  Objective: To evaluate the relationship between obesity and asthma.  Methods: This was a preliminary cross-sectional analysis involving 925 subjects with mild-to-moderate or severe asthma evaluated between 2013 and 2015. Obesity was defined on the basis of body mass index (BMI) and abdominal circumference. We collected clinical, laboratory, and anthropometric parameters, as well as pulmonary function test results and data regarding comorbidities. The subjects also completed asthma control and quality of life questionnaires.  Results: Obese individuals had a significantly higher number of neutrophils in peripheral blood than did nonobese individuals (p = 0.01). Among the obese individuals, 163 (61%) had positive skin-prick test results, as did 69% and 71% of the individuals classified as being overweight or normal weight, respectively. Obese individuals showed lower spirometric values than did nonobese individuals, and 32% of the obese individuals had uncontrolled asthma, a significantly higher proportion than that found in the other groups (p = 0.02).  Conclusions: Obese individuals with asthma seem to present with poorer asthma control and lower pulmonary function values than do nonobese individuals. The proportion of subjects with nonatopic asthma was higher in the obese group. Our results suggest that obese individuals with asthma show a distinct inflammatory pattern and are more likely to present with difficult-to-control asthma than are nonobese individuals.<\/jats:p>","DOI":"10.1590\/s1806-37562017000000034","type":"journal-article","created":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T18:40:30Z","timestamp":1532716830000},"page":"207-212","source":"Crossref","is-referenced-by-count":26,"title":["Obesity and asthma: clinical and laboratory characterization of a common combination"],"prefix":"10.1590","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7627-7298","authenticated-orcid":false,"given":"Juliana Pires Viana de","family":"Jesus","sequence":"first","affiliation":[{"name":"Universidade Federal da Bahia,  Brazil; Programa para o Controle da Asma na Bahia,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5043-0613","authenticated-orcid":false,"given":"Aline 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Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1475-2663","authenticated-orcid":false,"given":"Adelmir","family":"Souza-Machado","sequence":"additional","affiliation":[{"name":"Programa para o Controle da Asma na Bahia,  Brasil; Universidade Federal da Bahia,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4868-0124","authenticated-orcid":false,"given":"Eduardo Vieira","family":"Ponte","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brazil; Faculdade de Medicina de Jundia\u00ed,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7403-3871","authenticated-orcid":false,"given":"\u00c1lvaro Augusto","family":"Cruz","sequence":"additional","affiliation":[{"name":"Programa para o Controle da Asma na Bahia,  Brasil; Universidade Federal da Bahia,  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