{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:54:26Z","timestamp":1792166066575,"version":"4.4.0"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. bras. pneumol."],"abstract":"<jats:p>ABSTRACT  Objective: To evaluate the diagnostic accuracy of CT-guided percutaneous core needle biopsy (CT-CNB) of pulmonary nodules \u2264 2 cm, as well as to identify factors influencing the accuracy of the procedure and its morbidity.  Methods: This was a retrospective, single-center study of 170 consecutive patients undergoing CT-CNB of small pulmonary nodules (of \u2264 2 cm) between January of 2010 and August of 2015.  Results: A total of 156 CT-CNBs yielded a definitive diagnosis, the overall diagnostic accuracy being 92.3%. Larger lesions were associated with a higher overall accuracy (OR = 1.30; p = 0.007). Parenchymal hemorrhage occurring during the procedure led to lower accuracy rates (OR = 0.13; p = 0.022). Pneumothorax was the most common complication. A pleura-to-lesion distance &amp;gt; 3 cm was identified as a risk factor for pneumothorax (OR = 16.94), whereas performing a blood patch after biopsy was a protective factor for pneumothorax (OR = 0.18).  Conclusions: Small nodules (of &lt; 2 cm) represent a technical challenge for diagnosis. CT-CNB is an excellent diagnostic tool, its accuracy being high.<\/jats:p>","DOI":"10.1590\/s1806-37562017000000259","type":"journal-article","created":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T16:53:16Z","timestamp":1539190396000},"page":"307-314","source":"Crossref","is-referenced-by-count":26,"title":["CT-guided percutaneous core needle biopsy of pulmonary nodules smaller than 2 cm: technical aspects and factors influencing accuracy"],"prefix":"10.1590","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8274-1034","authenticated-orcid":false,"given":"Juliano Ribeiro de","family":"Andrade","sequence":"first","affiliation":[{"name":"Hospital Israelita Albert Einstein,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7599-583X","authenticated-orcid":false,"given":"Rafael Dahmer","family":"Rocha","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein,  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