{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:18:07Z","timestamp":1791890287410,"version":"4.3.4"},"reference-count":27,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,7,23]],"date-time":"2012-07-23T00:00:00Z","timestamp":1343001600000},"content-version":"vor","delay-in-days":326,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1590\/s1807-59322011000900002","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T07:07:57Z","timestamp":1761721677000},"page":"1519-1522","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["The prevalence of aminoglycoside-modifying enzyme genes (aac (6\u2032)-I, aac (6\u2032)-II, ant (2\u2033)-I, aph (3\u2032)-VI) in Pseudomonas aeruginosa"],"prefix":"10.1016","volume":"66","author":[{"given":"Farzam","family":"Vaziri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahin Najar","family":"Peerayeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qorban Behzadian","family":"Nejad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Farhadian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"suppl 41","key":"10.1590\/S1807-59322011000900002_bib1","first-page":"22","article-title":"Mechanisms of antibiotic resistance in Pseudomonas aeruginosa","volume":"95","author":"Lambert","year":"2002","journal-title":"J R Soc Med"},{"key":"10.1590\/S1807-59322011000900002_bib2","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/jac\/dki160","article-title":"Prevalence of Ambler class A and D \u03b2-lactamases among clinical isolates of Pseudomonas aeruginosa in Korea","volume":"56","author":"Park","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"10.1590\/S1807-59322011000900002_bib3","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1128\/AAC.44.3.710-712.2000","volume":"44","author":"Jalal","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1590\/S1807-59322011000900002_bib4","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0924-8579(00)00212-0","article-title":"Therapeutic guidelines for Pseudomonas aeruginosa infections","volume":"16","author":"Giamarellou","year":"2000","journal-title":"Int J antimicrob Agen"},{"key":"10.1590\/S1807-59322011000900002_bib5","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1093\/jac\/dkn174","article-title":"\u03b2-lactam and aminoglycoside resistance rates and mechanisms among Pseudomonas aeruginosa in French general practice (community and private healthcare centres)","volume":"62","author":"Dubois","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"10.1590\/S1807-59322011000900002_bib6","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1469-0691.2008.02097.x","article-title":"Chromosomal mechanisms of aminoglycoside resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients","volume":"15","author":"Islam","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"10.1590\/S1807-59322011000900002_bib7","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1099\/00221287-146-10-2543","article-title":"Role of Pseudomonas aeruginosa PhoP-PhoQ in resistance to antimicrobial cationic peptides and aminoglycosides","volume":"146","author":"Macfarlane","year":"2000","journal-title":"Microbiol"},{"key":"10.1590\/S1807-59322011000900002_bib8","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/glycob\/cwq047","article-title":"High-level antibiotic resistance in Pseudomonas aeruginosa biofilm: the ndvB gene is involved in the production of highly glycerol-phosphorylated \u03b2-(1\u21923)-glucans, which bind aminoglycosides","volume":"20","author":"Sadovskaya","year":"2010","journal-title":"Glycobiol"},{"key":"10.1590\/S1807-59322011000900002_bib9","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1128\/AAC.00443-07","article-title":"High prevalence of metallo- \u03b2-lactamase and 16S rRNA methylase coproduction among imipenem- resistant Pseudomonas aeruginosa isolates in Brazil","volume":"51","author":"Doi","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1590\/S1807-59322011000900002_bib10","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1128\/mr.57.1.138-163.1993","article-title":"Molecular genetics aminoglycoside resistance genes and familial relationship of the aminoglycoside modifying enzymes","volume":"57","author":"Shaw","year":"1993","journal-title":"Microbiol Rev"},{"key":"10.1590\/S1807-59322011000900002_bib11","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2174\/1568005023342533","article-title":"Aminoglycoside antibiotic resistance by enzymatic deactivation","volume":"2","author":"Smith","year":"2002","journal-title":"Curr Drug Targets Infect Disord"},{"key":"10.1590\/S1807-59322011000900002_bib12","doi-asserted-by":"crossref","first-page":"951","DOI":"10.3201\/eid1106.040924","article-title":"Global spread of multiple aminoglycoside resistance genes","volume":"11","author":"Yamane","year":"2005","journal-title":"Emerg Infect Dis"},{"issue":"Suppl. 2","key":"10.1590\/S1807-59322011000900002_bib13","first-page":"17","article-title":"The most frequently occurring aminoglycoside resistance mechanisms\u2014 combined results of surveys in eight regions of the world","volume":"7","author":"Miller","year":"1995","journal-title":"J Chemother"},{"key":"10.1590\/S1807-59322011000900002_bib14","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1128\/AAC.49.2.479-487.2005","article-title":"Aminoglycoside resistance in Pseudomonas aeruginosa","volume":"49","author":"Poole","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1590\/S1807-59322011000900002_bib15","unstructured":"Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; seventeenth informational supplement. CLSI document M100-S17. CLSI, 2007 Wayne, PA"},{"key":"10.1590\/S1807-59322011000900002_bib16","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/jac\/dkn244","article-title":"Occurrence and mechanisms of amikacin resistance and its association with \u03b2-lactamases in Pseudomonas aeruginosa: a Korean nationwide study","volume":"62","author":"Kim","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"10.1590\/S1807-59322011000900002_bib17","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1093\/jac\/dkm076","article-title":"Susceptibility of Pseudomonas aeruginosa to antimicrobials: a 2004 French multicentre hospital study","volume":"59","author":"Cavallo","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"10.1590\/S1807-59322011000900002_bib18","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S0305-4179(02)00024-4","article-title":"Frequency of Pseudomonas aeruginosa serotypes in burn wound infections and their resistance to antibiotics","volume":"28","author":"Estahbanati","year":"2002","journal-title":"Burns"},{"key":"10.1590\/S1807-59322011000900002_bib19","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1699-0463.1996.tb04940.x","article-title":"Aminoglycoside resistance mechanisms in Enterobacteriaceae and Pseudomonas spp. from two Danish hospitals: correlation with type of aminoglycoside used","volume":"104","author":"Busch-Sorensen","year":"1996","journal-title":"APMIS"},{"key":"10.1590\/S1807-59322011000900002_bib20","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1046\/j.1198-743x.2001.00284.x","article-title":"The changing nature of aminoglycoside resistance mechanisms and prevalence of newly recognized resistance mechanisms in Turkey","volume":"7","author":"Over","year":"2001","journal-title":"Clin Microbiol Infect"},{"key":"10.1590\/S1807-59322011000900002_bib21","first-page":"48","article-title":"Prevalence and mechanisms of aminoglycoside resistance","volume":"80","author":"Phillips","year":"1986","journal-title":"A ten-year study. Am J Med"},{"key":"10.1590\/S1807-59322011000900002_bib22","doi-asserted-by":"crossref","first-page":"S46","DOI":"10.1093\/clinids\/24.Supplement_1.S46","article-title":"The most frequent aminoglycoside resistance mechanisms changes with time and geographic area: a reflection of aminoglycoside usage patterns","volume":"24","author":"Miller","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1590\/S1807-59322011000900002_bib23","doi-asserted-by":"crossref","first-page":"57","DOI":"10.5145\/KJCM.2009.12.2.57","article-title":"Aminoglycoside Resistance in Gram-negative Bacilli","volume":"12","author":"Park","year":"2009","journal-title":"Korean J Clin Microbiol"},{"key":"10.1590\/S1807-59322011000900002_bib24","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.drup.2010.08.003","article-title":"Aminoglycoside modifying enzymes","volume":"13","author":"Ramirez","year":"2010","journal-title":"Drug Resist"},{"key":"10.1590\/S1807-59322011000900002_bib25","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1099\/jmm.0.009142-0","article-title":"Pseudomonas aeruginosa \u2013 a phenomenon of bacterial resistance","volume":"58","author":"Strateva","year":"2009","journal-title":"J Medic Microbiol"},{"key":"10.1590\/S1807-59322011000900002_bib26","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1021\/ja011695m","article-title":"Design of novel antibiotics that bind to the ribosomal acyltransfer site","volume":"124","author":"Haddad","year":"2002","journal-title":"J Am Chem Soc"},{"key":"10.1590\/S1807-59322011000900002_bib27","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.coph.2009.08.006","article-title":"Prospects for the next anti-Pseudomonas drug","volume":"9","author":"Page","year":"2009","journal-title":"Curr Opin Pharmacol"}],"container-title":["Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1807593222019366?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1807593222019366?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T07:10:19Z","timestamp":1761721819000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1807593222019366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S1807593222019366"],"URL":"https:\/\/doi.org\/10.1590\/s1807-59322011000900002","relation":{},"ISSN":["1807-5932"],"issn-type":[{"value":"1807-5932","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The prevalence of aminoglycoside-modifying enzyme genes (aac (6\u2032)-I, aac (6\u2032)-II, ant (2\u2033)-I, aph (3\u2032)-VI) in Pseudomonas aeruginosa","name":"articletitle","label":"Article Title"},{"value":"Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1590\/S1807-59322011000900002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 CLINICS. Published by Elsevier Spain","name":"copyright","label":"Copyright"}]}}