{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T12:14:33Z","timestamp":1775564073329,"version":"3.50.1"},"reference-count":11,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement. neuropsychol."],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:p>Abstract Alzheimer's disease (AD) is characterized by impairment in memory and autonomy, causing excessive pressure on family and an overburdened health care system. Early diagnosis, with the appropriate treatment, is important to reduce the pattern of disease progression.  Objective: The study sought to identify the most probable causes of delay in diagnosis.  Methods: A cross-sectional study involving AD patients followed at an Outpatient Geriatric Clinic from a tertiary public university hospital was conducted between June 2009 and February 2011.  Results: Ninety-four patients were evaluated (66% women), aged 77.76\u00b16.8 years and with median educational level of 3 years (95% CI 2.7-3.80). Regarding severity of dementia, 51.8% of patients were classified as having mild dementia (CDR 1), 40% moderate dementia (CDR 2) and 8.2% severe dementia (CDR 3). Mean educational level of caregivers was 8.3\u00b13.9 years. Among those who believed there was a delay, 36% stated that the \"family thought that the changes were normal for the age of the patient\" reporting average delay of 1.8 years (95% CI: 1.3-2.5) while 45.3% stated that the \"doctor did not reach a diagnosis\" reporting a median delay of 1.5 years (95% CI: 1.4-2.3).  Conclusion: Based on these results, it can be concluded the time between onset of symptoms and diagnosis was excessive. This study may be useful to help increase awareness of issues not sufficiently discussed in the literature, such as diagnostic delay and influence of caregivers' educational level on treatment.<\/jats:p>","DOI":"10.1590\/s1980-57642011dn05040011","type":"journal-article","created":{"date-parts":[[2016,7,23]],"date-time":"2016-07-23T13:15:04Z","timestamp":1469279704000},"page":"328-331","source":"Crossref","is-referenced-by-count":20,"title":["Factors influencing possible delay in the diagnosis of Alzheimer's disease Findings from a tertiary Public University Hospital"],"prefix":"10.1590","volume":"5","author":[{"given":"Lu\u00eds Felipe Jos\u00e9 Ravic de","family":"Miranda","sequence":"first","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael de Oliveira","family":"Matoso","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rlon Vieira","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thiago Oliveira Lemos de","family":"Lima","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano Fiorini","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Castro","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9bora Regina de Melo","family":"Moreira","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeferson Cruz","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas Jardim de","family":"Paula","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Alexandre V.","family":"Magno","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Caramelli","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edgar Nunes de","family":"Moraes","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Indicadores Sociodemogr\u00e1ficos e de Sa\u00fade no Brasil","year":"2009"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1159\/000109998","article-title":"Prevalence of Dementia in the United States: The Aging, Demographics, and Memory Study","volume":"29","author":"Plassman BL","year":"2007","journal-title":"Neuroepidemiology"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1017\/S1041610209009430","article-title":"Prevalence of dementia in Latin America: a collaborative study of population-based cohorts","volume":"21","author":"Nitrini R","year":"2009","journal-title":"Int Psychogeriatr"},{"key":"ref4","article-title":"Community based study of psychiatric disorders among the elderly living in delhi","volume":"7","author":"Chowdhury Archana","year":"2008","journal-title":"Int J Health"},{"key":"ref5","series-title":"Avalia\u00e7\u00e3o do Programa P\u00fablico Brasileiro de Tratamento da Doen\u00e7a de Alzheimer no ano de 2008","author":"Cintra MTG","year":"2008"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1001\/archinte.158.9.1021","article-title":"Donepezil Improves Cognition and Global Function in Alzheimer Disease","volume":"158","author":"Rogers SL","year":"1998","journal-title":"Arch Int Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":"Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group","volume":"34","author":"McKhann G","year":"1984","journal-title":"Neurology"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1212\/WNL.43.2.250","article-title":"Vascular dementia: diagnostic criteria for research studies. 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