{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T16:21:59Z","timestamp":1772468519423,"version":"3.50.1"},"reference-count":35,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Bras. Parasitol. Vet."],"abstract":"<jats:p>Abstract Cystic echinococcosis (CE) are commonly found in the liver and lungs of affected hosts. The treatment approach is usually surgical, or giving drugs in conjunction before surgery to kill protoscolices, to avoid anaphylactic shock from leakage of hydatid fluid into the peritoneum and to decrease opportunities for recurrences. The present study was to evaluate the in vitro scolicidal efficacy of hydroalcoholic extract of Punica granatum peel and Nigella sativa, on the protoscolices of CE that collected from the lungs of infected camels. Different concentrations of extracts with different exposure times were used and a viability assay was applied to measure the scolicidal effect. N. sativa showed its highest scolicidal efficacy at 100 mg\/mL and 10 mg\/mL concentrations after 30 and 60 min. P. granatum peel extract showed its maximum scolicidal efficacy at 100 mg\/mL concentration after 120 min. All experiments of the current study revealed that the extracts of both N. sativa and P. granatum had a scolicidal effects on the protoscolices of camel hydatid cysts. It could be concluded that N. sativa extract is more potent than P. granatum peel extract regarding scolicidal effect, but the efficacies of both extracts were of moderate significant correlation to exposure time and concentrations.<\/jats:p>","DOI":"10.1590\/s1984-29612019019","type":"journal-article","created":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T15:35:24Z","timestamp":1560353724000},"page":"210-214","source":"Crossref","is-referenced-by-count":6,"title":["In-vitro evaluation of Nigella sativa and Punica granatum effect on protoscolices of hydatid cysts"],"prefix":"10.1590","volume":"28","author":[{"given":"Nasr Moawad","family":"El-Bahy","sequence":"first","affiliation":[{"name":"Sadat City University,  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amer Ragheb","family":"Abdelaziz","sequence":"additional","affiliation":[{"name":"Sohag University,  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1810-9501","authenticated-orcid":false,"given":"Reda Elbastawisy","family":"Khalafalla","sequence":"additional","affiliation":[{"name":"Kafrelsheikh University,  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2019,4]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.bjbas.2018.02.003","article-title":"In vitro and in vivo anthelmintic activity of pumpkin seeds and pomegranate peels extracts against Ascaridia galli.","volume":"7","author":"Abdelaziz ARA","year":"2018","journal-title":"Beni-Suef Univ J Basic Appl Sci"},{"issue":"2","key":"ref2","first-page":"511","article-title":"Effect of Nigella sativa and Allium cepa oils on Trichinella spiralis in experimentally infected rats","volume":"35","author":"Abu El Ezz NM","year":"2005","journal-title":"J Egypt Soc Parasitol"},{"issue":"5","key":"ref3","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S2221-1691(13)60075-1","article-title":"A review on therapeutic potential of Nigella sativa: A miracle herb","volume":"3","author":"Ahmad A","year":"2013","journal-title":"Asian Pac J Trop Biomed"},{"key":"ref4","first-page":"17","article-title":"Efficacy of Punica granatum Linn. 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