{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:28:31Z","timestamp":1791494911263,"version":"4.3.4"},"reference-count":38,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Bras. Parasitol. Vet."],"abstract":"<jats:p>Abstract Canine visceral leishmaniasis is a disease caused by the protozoon Leishmania infantum, an important agent of zoonotic concern. In this study we determined the seroprevalence, risk factors and spatial distribution of infection by L. infantum among dogs in the Paje\u00fa microregion of the Sert\u00e3o region of Pernambuco, Brazil. Canine serum samples (n = 247) were tested using the Dual Path Platform (DPP\u00ae) rapid screening test and ELISA\/S7\u00ae confirmatory test; and risk factors were assessed through univariate analysis and logistical regression. The spatial distribution of reactive dogs was analyzed by drawing a map using QGIS. Seroprevalence of 13.7% (34\/247) was detected, with cases predominating in the municipality of Tabira (26.4%; 9\/34). Age above 10 years was considered to be a risk factor associated with the presence of anti-L. infantum antibodies. The high overall prevalence and spatial distribution of positive cases showed wide dispersion of reagents dogs in the study area. Therefore, preventive measures are needed in order to reduce the risk of infection for animals and humans.<\/jats:p>","DOI":"10.1590\/s1984-29612023029","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T12:38:12Z","timestamp":1684759092000},"source":"Crossref","is-referenced-by-count":14,"title":["Canine visceral leishmaniasis: risk factors and spatial analysis in an endemic area of Northeastern Brazil"],"prefix":"10.1590","volume":"32","author":[{"given":"Samuel Souza","family":"Silva","sequence":"first","affiliation":[{"name":"Universidade Federal do Agreste de Pernambuco,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia Oliveira de","family":"Macedo","sequence":"additional","affiliation":[{"name":"Universidade Federal do Agreste de Pernambuco,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9ssica Cardoso Pessoa de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Federal do Agreste de Pernambuco,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leucio C\u00e2mara","family":"Alves","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural de Pernambuco,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00edlcia Aparecida de","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Universidade Federal do Agreste de Pernambuco,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0347-9358","authenticated-orcid":false,"given":"Rafael Antonio Nascimento","family":"Ramos","sequence":"additional","affiliation":[{"name":"Universidade Federal do Agreste de Pernambuco,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2023]]},"reference":[{"issue":"3","key":"ref1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004349","article-title":"A historical overview of the classification, evolution, and dispersion of Leishmania parasites and sandflies","volume":"10","author":"Akhoundi M","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"issue":"Pt A","key":"ref2","article-title":"Seroepidemiology of visceral leishmaniasis among free-roaming dogs and children in Zahedan city, southeast of Iran, 2018-2020","volume":"161","author":"Akhtardanesh B","year":"2021","journal-title":"Microb Pathog"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1476-072X-13-13","article-title":"Prediction of high-risk areas for visceral leishmaniasis using socioeconomic indicators and remote sensing data","volume":"13","author":"Almeida AS","year":"2014","journal-title":"Int J Health Geogr"},{"issue":"4","key":"ref4","article-title":"Operational difficulties in the use of insecticidal dog collars for the control of visceral leishmaniasis, municipality of Montes Claros, MG, Brazil, 2012","volume":"27","author":"Alves EB","year":"2018","journal-title":"Epidemiol Serv Saude"},{"key":"ref5","first-page":"41","article-title":"Epidemiological aspects and risk factors for infection by Leishmania infantum chagasi in dogs from municipality of Petrolina, Northeastern Brazil","volume":"3-4","author":"Araujo AC","year":"2016","journal-title":"Vet Parasitol Reg Stud Reports"},{"key":"ref6","article-title":"Space-time analysis of the incidence of human visceral leishmaniasis (VL) and prevalence of canine VL in a municipality of southeastern Brazil: identification of priority areas for surveillance and control","volume":"197","author":"Arruda RMF","year":"2019","journal-title":"Acta Trop"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"653","DOI":"10.5216\/cab.v11i3.5933","article-title":"Soropreval\u00eancia e vari\u00e1veis epidemiol\u00f3gicas associadas \u00e0 leishmaniose visceral canina em \u00e1rea end\u00eamica no munic\u00edpio de S\u00e3o Lu\u00eds, Maranh\u00e3o, Brasil","volume":"11","author":"Barbosa DS","year":"2010","journal-title":"Ci\u00eanc Anim Bras"},{"issue":"2","key":"ref8","first-page":"209","article-title":"Eco-epidemiological aspects of visceral leishmaniasis in the municipality of Diamantina, Jequitinhonha Valley (Minas Gerais State, Brazil)","volume":"94","author":"Batista-Santos F","year":"2021","journal-title":"Yale J Biol Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.prevetmed.2017.07.011","article-title":"Reliability of techniques used in the diagnosis of canine visceral leishmaniasis by the national control program in Brazil: a survey in an area of recent transmission","volume":"146","author":"Belo VS","year":"2017","journal-title":"Prev Vet Med"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s11686-020-00294-z","article-title":"Leishmania infantum infection in a domestic cat: a real threat or an occasional finding?","volume":"66","author":"Berenguer LKAR","year":"2021","journal-title":"Acta Parasitol"},{"issue":"1","key":"ref11","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1186\/s12879-020-05125-0","article-title":"Canine serological survey and dog culling and its relationship with human visceral leishmaniasis in an endemic urban area","volume":"20","author":"Bermudi PMM","year":"2020","journal-title":"BMC Infect Dis"},{"issue":"12","key":"ref12","doi-asserted-by":"crossref","first-page":"4091","DOI":"10.1007\/s00436-021-07072-4","article-title":"Didelphis spp. opossums and their parasites in the Americas: a one health perspective","volume":"120","author":"Bezerra-Santos MA","year":"2021","journal-title":"Parasitol Res"},{"key":"ref13","series-title":"Manual de vigil\u00e2ncia e controle da leishmaniose visceral","year":"2014"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1590\/S0102-09352012000600017","article-title":"Caracteriza\u00e7\u00e3o demogr\u00e1fica das popula\u00e7\u00f5es de c\u00e3es e gatos supervisionados do munic\u00edpio de S\u00e3o Paulo","volume":"64","author":"Canatto BD","year":"2012","journal-title":"Arq Bras Med Vet Zootec"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","DOI":"10.1590\/s1984-29612020017","article-title":"Canine visceral leishmaniasis: perception, prevalence, and spatial distribution in municipality of Nossa Senhora do Livramento, Mato Grosso, Brazil","volume":"29","author":"Carvalho MR","year":"2020","journal-title":"Rev Bras Parasitol Vet"},{"issue":"2","key":"ref16","article-title":"Controle da leishmaniose visceral canina por eutan\u00e1sia: estimativa de efeito baseado em inqu\u00e9rito e modelagem matem\u00e1tica","volume":"36","author":"Costa DNCC","year":"2020","journal-title":"Cad Saude Publica"},{"issue":"1-2","key":"ref17","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.vetpar.2006.03.008","article-title":"Seroepidemiological survey on canine leishmaniasis among dogs from an urban area of Brazil","volume":"140","author":"Dantas-Torres F","year":"2006","journal-title":"Vet Parasitol"},{"issue":"2","key":"ref18","article-title":"Canine leishmaniasis in the semi-arid region of Pernambuco, northeastern Brazil: epidemiology, factors associated with seropositivity and spatial analysis","volume":"29","author":"Evaristo AMCF","year":"2020","journal-title":"Rev Bras Parasitol Vet"},{"issue":"4","key":"ref19","doi-asserted-by":"crossref","first-page":"23","DOI":"10.56242\/globalhealth;2021;1;4;23-29","article-title":"Detection and molecular characterization of Leishmania in dogs from northeastern Brazil","volume":"1","author":"Evaristo AMCF","year":"2021","journal-title":"Braz J Glo Health"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1093\/jme\/tjaa199","article-title":"Detection of Pintomyia fischeri (Diptera: Psychodidae) with Leishmania infantum (Trypanosomatida: Trypanosomatidae) promastigotes in a focus of visceral leishmaniasis in Brazil","volume":"58","author":"Galvis-Ovallos F","year":"2021","journal-title":"J Med Entomol"},{"key":"ref21","series-title":"IBGE cidades","year":"2022"},{"issue":"5","key":"ref22","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1590\/0037-8682-0087-2018","article-title":"Seroprevalence and spatial distribution of canine leishmaniasis in an endemic region in Brazil: how has the situation changed after 10 years?","volume":"51","author":"Lins TNB","year":"2018","journal-title":"Rev Soc Bras Med Trop"},{"issue":"2","key":"ref23","first-page":"67","article-title":"Sazonalidade de flebotom\u00edneos em \u00e1rea end\u00eamica de leishmaniose visceral no munic\u00edpio de Sobral, Cear\u00e1, Brasil","volume":"18","author":"Macedo ITF","year":"2008","journal-title":"Ci\u00eanc Anim"},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1007\/s00436-022-07661-x","article-title":"Vector-borne pathogens of zoonotic concern in dogs from a Quilombola community in northeastern Brazil","volume":"121","author":"Macedo LO","year":"2022","journal-title":"Parasitol Res"},{"issue":"6","key":"ref25","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1590\/0037-8682-0042-2014","article-title":"Outbreak of canine visceral leishmaniasis in Barra Mansa, State of Rio de Janeiro","volume":"47","author":"Mello CX","year":"2014","journal-title":"Rev Soc Bras Med Trop"},{"issue":"11","key":"ref26","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1007\/s00436-021-07319-0","article-title":"Canine leishmaniasis in an endemic region, Northeastern Brazil: a comparative study with four groups of animals","volume":"120","author":"Oliveira MR","year":"2021","journal-title":"Parasitol Res"},{"issue":"12","key":"ref27","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.3390\/microorganisms9122627","article-title":"Comparative study of real-time PCR (TaqMan Probe and Sybr Green), Serological techniques (ELISA, IFA and DAT) and clinical signs evaluation, for the diagnosis of canine leishmaniasis in experimentally infected dogs","volume":"9","author":"Peris MP","year":"2021","journal-title":"Microorganisms"},{"issue":"4","key":"ref28","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1590\/0037-8682-0224-2014","article-title":"Prevalence of zoonotic visceral leishmaniasis in dogs in an endemic area of Brazil","volume":"48","author":"Pimentel DS","year":"2015","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref29","series-title":"Estat\u00edstica aplicada \u00e0 pesquisa em ci\u00eancia veterin\u00e1ria","author":"Reis JC","year":"2003"},{"issue":"1-2","key":"ref30","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.vetpar.2008.04.014","article-title":"Cross-sectional serological study of canine Leishmania infection in Fortaleza, Cear\u00e1 state, Brazil","volume":"155","author":"Rondon FCM","year":"2008","journal-title":"Vet Parasitol"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ijppaw.2014.08.004","article-title":"Wild and synanthropic reservoirs of Leishmania species in the Americas","volume":"3","author":"Roque ALR","year":"2014","journal-title":"Int J Parasitol Parasites Wildl"},{"issue":"1","key":"ref32","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s13071-019-3383-1","article-title":"Home sweet home: sand flies find a refuge in remote indigenous villages in north-eastern Brazil, where leishmaniasis is endemic","volume":"12","author":"Sales KGS","year":"2019","journal-title":"Parasit Vectors"},{"issue":"10","key":"ref33","doi-asserted-by":"crossref","first-page":"236","DOI":"10.3390\/vetsci8100236","article-title":"Seroprevalence and risk factors associated with canine leishmaniasis in Egypt","volume":"8","author":"Selim A","year":"2021","journal-title":"Vet Sci"},{"issue":"14","key":"ref34","article-title":"Epidemiologia da leishmaniose visceral humana em Petrolina, Pernambuco, no per\u00edodo de 2009 a 2020: uma an\u00e1lise descritiva","volume":"10","author":"Silva MMS","year":"2021","journal-title":"Res Soc Dev"},{"issue":"5","key":"ref35","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1590\/0037-8682-0047-2018","article-title":"Demographic and clinical characterization of human visceral leishmaniasis in the State of Pernambuco, Brazil between 2006 and 2015","volume":"51","author":"Sousa JMS","year":"2018","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref36","series-title":"Epidemiologia veterin\u00e1ria","author":"Thrusfield MV","year":"2004"},{"key":"ref37","article-title":"Socio-economic and environmental factors associated with the occurrence of canine infection by Leishmania infantum in Teresina, Brazil","volume":"24","author":"Veloso ECM","year":"2021","journal-title":"Vet Parasitol Reg Stud Reports"},{"key":"ref38","series-title":"Leishmaniasis","year":"2022"}],"container-title":["Revista Brasileira de Parasitologia Veterin\u00e1ria"],"original-title":["Leishmaniose visceral canina: fatores de risco e an\u00e1lise espacial em uma \u00e1rea end\u00eamica do Nordeste do Brasil"],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S1984-29612023000200307&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T12:38:48Z","timestamp":1684759128000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1984-29612023000200307&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":38,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023]]}},"alternative-id":["S1984-29612023000200307"],"URL":"https:\/\/doi.org\/10.1590\/s1984-29612023029","relation":{},"ISSN":["1984-2961","0103-846X"],"issn-type":[{"value":"1984-2961","type":"electronic"},{"value":"0103-846X","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]},"article-number":"e003223"}}