{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:48:47Z","timestamp":1777445327029,"version":"3.51.4"},"reference-count":23,"publisher":"FapUNIFESP (SciELO)","issue":"4","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Bras. Parasitol. Vet."],"abstract":"<jats:p>Abstract Many studies about fasciolosis control have been carried out, whether acting on the adult parasite or in Pseudosuccinea columella, compromising the development of the larval stages. The present study aimed to evaluate, under laboratory conditions, the susceptibility of P. columella to Heterorhabditis bacteriophora HP88, during for 24 and 48 hours of exposure. The snails were evaluated for 21 days for accumulated mortality; number of eggs laid; hatchability rate; biochemical changes; and histopathological analysis. We found that exposure induced a reduction in glucose and glycogen levels, characterizing a negative energy balance, due to the depletion of energy reserves as a result of the direct competition established by the nematode\/endosymbiont bacteria complex in such substrates. A mortality rate of 48.25% and 65.52% was observed in the group exposed for 24 h and 48 h, respectively, along with significant impairment of reproductive biology in both exposed groups in relation to the respective controls. The results presented here show that P. columella is susceptible to the nematode H. bacteriophora, with the potential to be used as an alternative bioagent in the control of this mollusk, especially in areas considered endemic for fascioliasis, in line with the position expressed by the World Health Organization Health.<\/jats:p>","DOI":"10.1590\/s1984-29612023072","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T12:21:11Z","timestamp":1701087671000},"source":"Crossref","is-referenced-by-count":2,"title":["Influence of exposure Heterorhabditis bacteriophora HP88, (Rhabditida: Heterorhabditidae) on biological and physiological parameters of Pseudosuccinea columella (Basommatophora: Lymnaeidae)"],"prefix":"10.1590","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8076-5705","authenticated-orcid":false,"given":"Nat\u00e2nia do Carmo","family":"Sperandio","sequence":"first","affiliation":[{"name":"Universidade Federal do Esp\u00edrito Santo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor Menezes","family":"Tunholi","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludimila Santos","family":"Amaral","sequence":"additional","affiliation":[{"name":"Universidade Federal do Esp\u00edrito Santo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Larissa Bitencourt","family":"Vidal","sequence":"additional","affiliation":[{"name":"Universidade Federal de Vi\u00e7osa,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lais Sperandio","family":"Cassani","sequence":"additional","affiliation":[{"name":"Universidade Federal do Esp\u00edrito Santo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vin\u00edcius Menezes","family":"Tunholi-Alves","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa Carvalho Machado do","family":"Couto-Chambarelli","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jankerle Neves","family":"Boeloni","sequence":"additional","affiliation":[{"name":"Universidade Federal do Esp\u00edrito Santo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caio","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8700-3065","authenticated-orcid":false,"given":"Isabella Vilhena Freire","family":"Martins","sequence":"additional","affiliation":[{"name":"Universidade Federal do Esp\u00edrito Santo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2023]]},"reference":[{"key":"ref1","article-title":"Heterorhabditis bacteriophora (Rhabditida: Heterorhabditidae), isolate HP88, induces reproductive and physiological alterations in Biomphalaria glabrata (Gastropoda: Planorbidae): an alternative for biological control of schistosomiasis","volume":"230","author":"Amaral LS","year":"2022","journal-title":"Acta Trop"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1590\/S0036-46652014000100005","article-title":"Fasciola hepatica in bovines in Brazil: data availability and spatial distribution","volume":"56","author":"Bennema SC","year":"2014","journal-title":"Rev Inst Med Trop S\u00e3o Paulo"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1590\/S0102-695X2010000200024","article-title":"Atividade moluscicida de plantas: uma alternativa 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