{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T19:48:36Z","timestamp":1776282516477,"version":"3.50.1"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa Cient\u00edfica e Tecnol\u00f3gica da UFRRJ"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Bras. Parasitol. Vet."],"abstract":"<jats:p>Abstract Lice and mange represent common ectoparasitic infestations in domestic cats, affecting their health and well-being. The study evaluated the efficacy of a topical formulation containing 12.5% fipronil + 0.83% moxidectin + 8.3% praziquantel against common feline ectoparasites Otodectes cynotis, Notoedres cati and Felicola subrostratus. For the ear mite study, a controlled trial was conducted on cats naturally infested with O. cynotis. For the other two parasites, field studies were conducted on naturally infested cats. Cats in the treated group received a single topical dose of formulation. Parasite counts were performed at various time points post-treatment to assess efficacy. The results demonstrated the formulation was highly effective against all three parasites, achieving 100% efficacy after 3 days of treatment. The product was well-tolerated and safe, making it a suitable option for the treatment of feline ectoparasitosis.<\/jats:p>","DOI":"10.1590\/s1984-29612025080","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T18:22:19Z","timestamp":1776277339000},"source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of a single-dose topical formulation combining Fipronil, Moxidectin and Praziquantel against natural infestations of Notoedres cati, Otodectes cynotis and Felicola subrostratus in cats"],"prefix":"10.1590","volume":"35","author":[{"given":"Diefrey Ribeiro","family":"Campos","sequence":"first","affiliation":[{"name":"Universidade Federal Rural Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6057-9649","authenticated-orcid":false,"given":"Eduardo Fellipe Melo Santos","family":"Soares","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Breno Cayeiro","family":"Cruz","sequence":"additional","affiliation":[{"name":"Ourofino Sa\u00fade Animal Ltda,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela Pereira Sal\u00e7a de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gessica Ariane de Melo","family":"Cruz","sequence":"additional","affiliation":[{"name":"Ourofino Sa\u00fade Animal Ltda,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milenni Garcia","family":"Michels","sequence":"additional","affiliation":[{"name":"Ourofino Sa\u00fade Animal Ltda,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinando Nielsen de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Ourofino Sa\u00fade Animal Ltda,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor Renan Honorato","family":"Gatto","sequence":"additional","affiliation":[{"name":"Ourofino Sa\u00fade Animal Ltda,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thais Ribeiro","family":"Correia","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio Barbour","family":"Scott","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.5455\/javar.2019.f308","article-title":"Pharmacokinetics of combination antiparasitic drug preparation for dogs and cats in the form of spot-on solution","volume":"6","author":"Arisov 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