{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T16:08:07Z","timestamp":1778861287312,"version":"3.51.4"},"reference-count":40,"publisher":"FapUNIFESP (SciELO)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100020648","name":"Universidade Estadual de Santa Cruz","doi-asserted-by":"crossref","award":["PROPP\/UESC 073.0886.2022. 0034488-66"],"award-info":[{"award-number":["PROPP\/UESC 073.0886.2022. 0034488-66"]}],"id":[{"id":"10.13039\/501100020648","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100020648","name":"Universidade Estadual de Santa Cruz","doi-asserted-by":"crossref","award":["406083\/2022-6"],"award-info":[{"award-number":["406083\/2022-6"]}],"id":[{"id":"10.13039\/501100020648","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Instituto Nacional de Ci\u00eancia e Tecnologia em Bioinsumos Inovadores","award":["PROPP\/UESC 073.0886.2022. 0034488-66"],"award-info":[{"award-number":["PROPP\/UESC 073.0886.2022. 0034488-66"]}]},{"name":"Instituto Nacional de Ci\u00eancia e Tecnologia em Bioinsumos Inovadores","award":["406083\/2022-6"],"award-info":[{"award-number":["406083\/2022-6"]}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["PROPP\/UESC 073.0886.2022. 0034488-66"],"award-info":[{"award-number":["PROPP\/UESC 073.0886.2022. 0034488-66"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["406083\/2022-6"],"award-info":[{"award-number":["406083\/2022-6"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Bras. Parasitol. Vet."],"abstract":"<jats:p>Abstract The search for sustainable alternatives to manage gastrointestinal nematodes in small ruminants has intensified due to rising anthelmintic resistance. This study evaluated in vitro the efficacy of several Brazilian isolates of the genus Metarhizium spp. on gastrointestinal nematodes (GINs) of goats which were naturally infected with mixed populations predominantly composed of Haemonchus spp. (63%), Trichostrongylus spp. (35%), and Oesophagostomum spp. (2%). Biological assays were conducted using quantitative coproculture after 10 days of incubation, and SEM was performed after 72 h of fungus\u2013larva interaction. Isolates LCM S05, LCM S10, LCM S11, LCM S13, LCM S14, and LCM S15 promoted larval reduction of: 50.24%, 43.29%, 44.99%, 55.45%, 52.52%, and 67.95%, respectively. Isolate LCM S15, which showed the greatest reduction in larvae, was tested at concentrations of 1.0 \u00d7 106, 1.0 \u00d7 107, and 1.0 \u00d7 108 conidia\/mL, resulting in reductions in larvae of 36.90%, 50.17%, and 68.28%, respectively. In SEM, photomicrographs demonstrated that conidia adhered to and germinated on the nematode integument. This study demonstrates the potential of Brazilian isolates of Metarhizium spp. for the control of GINs in goats and highlights the route of fungal infection through the integument.<\/jats:p>","DOI":"10.1590\/s1984-296120260010","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T15:12:44Z","timestamp":1778857964000},"source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of Metarhizium spp. against gastrointestinal nematodes in goats and evidence of conidia infection through the integument"],"prefix":"10.1590","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7912-2419","authenticated-orcid":false,"given":"Ially de Almeida","family":"Moura","sequence":"first","affiliation":[{"name":"Universidade Estadual de Santa Cruz,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Wesley Oliveira da","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayara Mac\u00eado","family":"Barrozo","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tha\u00eds Almeida","family":"Corr\u00eaa","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia Silva","family":"G\u00f4lo","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabele da Costa","family":"\u00c2ngelo","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caio M\u00e1rcio de Oliveira","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9verton Kort Kamp","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00e2nia Rita Elias Pinheiro","family":"Bittencourt","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre Dias","family":"Munhoz","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Santa Cruz,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendell Marcelo de Souza","family":"Perinotto","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro,  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