{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T07:09:03Z","timestamp":1777360143447,"version":"3.51.4"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dental Press J. Orthod."],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p>OBJECTIVE: The purpose of this study was to evaluate the cephalometric alterations in patients with Angle Class II division 1 malocclusion, orthodontically treated with extraction of two maxillary premolars. METHODS: The sample comprised 68 initial and final lateral cephalograms of 34 patients of both gender (mean initial age of 14.03 years and mean final age of 17.25 years), treated with full fixed appliances and extraction of the first maxillary premolars. In order to evaluate the alterations due the treatment between initial and final phases, the dependent t test was applied to the studied cephalometric variables. RESULTS: The dentoskeletal alterations due to extraction of two maxillary premolars in the Class II division 1 malocclusion were: maxillary retrusion, improvement of the maxillomandibular relation, increase of lower anterior face height, retrusion of the maxillary incisors, buccal inclination, protrusion and extrusion of the mandibular incisors, besides the reduction of overjet and overbite. The tissue alterations showed decrease of the facial convexity and retrusion of the upper lip. CONCLUSIONS: The extraction of two maxillary premolars in Class II division 1 malocclusion promotes dentoskeletal and tissue alterations that contribute to an improvement of the relation between the bone bases and the soft tissue profile.<\/jats:p>","DOI":"10.1590\/s2176-94512013000400010","type":"journal-article","created":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T15:51:10Z","timestamp":1386172270000},"page":"61-69","source":"Crossref","is-referenced-by-count":9,"title":["Cephalometric changes in Class II division 1 patients treated with two maxillary premolars extraction"],"prefix":"10.1590","volume":"18","author":[{"given":"Marisana Piano","family":"Seben","sequence":"first","affiliation":[{"name":"Faculdade Ing\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabricio Pinelli","family":"Valarelli","sequence":"additional","affiliation":[{"name":"Faculdade Ing\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina Maria Salvatore de","family":"Freitas","sequence":"additional","affiliation":[{"name":"University of Toronto,  Brazi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Hermont","family":"Can\u00e7ado","sequence":"additional","affiliation":[{"name":"University of Toronto,  Brazi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aristeu Correa","family":"Bittencourt Neto","sequence":"additional","affiliation":[{"name":"Faculdade Ing\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"2","key":"ref1","first-page":"167","article-title":"The influence of extraction treatment on Holdaway soft-tissue measurements","volume":"74","author":"Basciftci FA","year":"2004","journal-title":"Angle Orthod","ISSN":"https:\/\/id.crossref.org\/issn\/0003-3219","issn-type":"print"},{"issue":"4","key":"ref2","first-page":"10","article-title":"The 6th key to facial beauty and TMJ health","volume":"4","author":"Bowbeer GR","year":"1987","journal-title":"Funct Orthod","ISSN":"https:\/\/id.crossref.org\/issn\/8756-3150","issn-type":"print"},{"issue":"8","key":"ref3","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.14219\/jada.archive.1999.0371","article-title":"More than lip service: facial esthetics in orthodontics","volume":"130","author":"Bowman SJ","year":"1999","journal-title":"J Am Dent Assoc","ISSN":"https:\/\/id.crossref.org\/issn\/0002-8177","issn-type":"print"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/ortho\/24.1.25","article-title":"Comparison of the changes in facial profile after orthodontic treatment, with and without extractions","volume":"24","author":"Bravo LA","year":"1997","journal-title":"Br J Orthod","ISSN":"https:\/\/id.crossref.org\/issn\/0301-228X","issn-type":"print"},{"issue":"4","key":"ref5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0889-5406(05)81334-4","article-title":"The effects of extraction versus nonextraction orthodontic treatment on the growth of the lower anterior face height","volume":"104","author":"Chua AL","year":"1993","journal-title":"Am J Orthod Dentofacial Orthop","ISSN":"https:\/\/id.crossref.org\/issn\/0889-5406","issn-type":"print"},{"issue":"4","key":"ref6","first-page":"21","article-title":"An orthodontic challenge","volume":"14","author":"Eirew HL","year":"1976","journal-title":"Int J Orthod","ISSN":"https:\/\/id.crossref.org\/issn\/0020-7500","issn-type":"print"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.ajodo.2005.08.045","article-title":"Profile changes of patients treated with and without premolar extractions","volume":"132","author":"Erdinc AE","year":"2007","journal-title":"Am J Orthod Dentofacial Orthop","ISSN":"https:\/\/id.crossref.org\/issn\/0889-5406","issn-type":"print"},{"issue":"1","key":"ref8","first-page":"8","article-title":"Estudo longitudinal das altera\u00e7\u00f5es do \u00e2ngulo naso-labial, em jovens com Classe II, 1\u00aa divis\u00e3o, que se submeteram ao tratamento ortod\u00f4ntico corretivo","volume":"32","author":"Freitas MR","year":"1999","journal-title":"Ortodontia","ISSN":"https:\/\/id.crossref.org\/issn\/0030-5944","issn-type":"print"},{"issue":"3","key":"ref9","first-page":"145","article-title":"1990 JCO study of orthodontic diagnosis and treatment procedures: 1. 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