{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T01:03:47Z","timestamp":1773882227383,"version":"3.50.1"},"reference-count":60,"publisher":"FapUNIFESP (SciELO)","issue":"suppl 3","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ci\u00eanc. sa\u00fade coletiva"],"abstract":"<jats:p>Abstract Rheumatoid arthritis (RA) is among the most prevalent chronic autoimmune and inflammatory diseases worldwide. The aim of this study was to establish a pooled estimate of the RA prevalence in South America by means of a meta-analysis of the available epidemiologic studies. Systematic searches in PubMed, Lilacs, SciELO, Scopus, and Web of Science databases (updated May 2019) were done followed by a systematic grey literature search to identify original research articles and reports, published after 2000, providing data of RA prevalence in any South American country. Proportion meta-analysis of weighted pooled was performed, with between-trial heterogeneity assessed by the inconsistency relative index. Sensitivity analyses and sub-group analyses were also done. A total of 25 articles, representing 27 population-based studies were included. Pooled prevalence of RA resulted in 0.48% with 591,981 cases in a population of 114,537,812 individuals (I2=99%). Brazil and Colombia presented the lowest rates of RA prevalence 0.22%, and 0.24%, respectively. RA prevalence in indigenous population was higher 1.45%, and studies using COPCORD method reported also the highest rates 1.07%.<\/jats:p>","DOI":"10.1590\/1413-812320212611.3.05152020","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T12:25:13Z","timestamp":1636979113000},"page":"5371-5382","source":"Crossref","is-referenced-by-count":15,"title":["Prevalence of rheumatoid arthritis in South America: a systematic review and meta-analysis"],"prefix":"10.1590","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4813-0675","authenticated-orcid":false,"given":"Jaqueline L.","family":"Germano","sequence":"first","affiliation":[{"name":"Secretaria de Estado da Sa\u00fade do Paran\u00e1,  Brasil; Universidade Federal do Paran\u00e1,  Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0314-8233","authenticated-orcid":false,"given":"Joana","family":"Reis-Pardal","sequence":"additional","affiliation":[{"name":"Santa Casa da Miseric\u00f3rdia de Lisboa,  Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4262-8608","authenticated-orcid":false,"given":"Fernanda S.","family":"Tonin","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1,  Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7049-4363","authenticated-orcid":false,"given":"Roberto","family":"Pontarolo","sequence":"additional","affiliation":[{"name":"UFPR,  Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8538-2903","authenticated-orcid":false,"given":"Ana C.","family":"Melchiors","sequence":"additional","affiliation":[{"name":"UFPR,  Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8529-9595","authenticated-orcid":false,"given":"Fernando","family":"Fernandez-Llimos","sequence":"additional","affiliation":[{"name":"Universidade do Porto,  Portugal"}]}],"member":"530","published-online":{"date-parts":[[2021,10]]},"reference":[{"issue":"9","key":"ref1","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1002\/art.27584","article-title":"2010 rheumatoid arthritis classification criteria an American College of Rheumatology\/European League Against Rheumatism collaborative initiative","volume":"62","author":"Aletaha D","year":"2010","journal-title":"Arthritis Rheum"},{"issue":"7","key":"ref2","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1136\/annrheumdis-2013-204627","article-title":"The global burden of rheumatoid arthritis estimates from the global burden of disease 2010 study","volume":"73","author":"Cross M","year":"2014","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jbspin.2012.02.005","article-title":"Mortality in rheumatoid arthritis over the last fifty years systematic review and 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