{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T02:08:02Z","timestamp":1772849282822,"version":"3.50.1"},"reference-count":10,"publisher":"FapUNIFESP (SciELO)","issue":"6 suppl 1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An. Bras. Dermatol."],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:p>Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.<\/jats:p>","DOI":"10.1590\/abd1806-4841.20132170","type":"journal-article","created":{"date-parts":[[2014,1,30]],"date-time":"2014-01-30T19:47:25Z","timestamp":1391111245000},"page":"166-169","source":"Crossref","is-referenced-by-count":12,"title":["Diffuse neurofibroma - an uncommon cause of alopecia"],"prefix":"10.1590","volume":"88","author":[{"given":"Vasco Coelho","family":"Macias","sequence":"first","affiliation":[{"name":"Hospital de Curry Cabral,  Portugal"}]},{"given":"Margarida","family":"Rafael","sequence":"additional","affiliation":[{"name":"Instituto Portugu\u00eas de Oncologia Francisco Gentil,  Portugal"}]},{"given":"C\u00e2ndida","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Hospital de Curry Cabral,  Portugal"}]},{"given":"Joaninha Costa","family":"Rosa","sequence":"additional","affiliation":[{"name":"Instituto Portugu\u00eas de Oncologia Francisco Gentil,  Portugal"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.2340\/00015555-0160","article-title":"Review of scalp alopecia due to a clinically unapparent or minimally apparent neoplasm (SACUMAN)","volume":"86","author":"Scheinfeld N","year":"2006","journal-title":"Acta Derm Venereol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1067\/mjd.2003.141","article-title":"Diffuse neurofibroma on the lower back","volume":"48","author":"van Zuuren EJ","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"46","DOI":"10.5021\/ad.2009.21.1.46","article-title":"A Case of Diffuse Neurofibroma of the Scalp","volume":"21","author":"Yoo KH","year":"2009","journal-title":"Ann Dermatol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1097\/00000372-199410000-00003","article-title":"Histopathological variants of neurofibroma: a study of 114 cases","volume":"16","author":"Megahed M","year":"1994","journal-title":"Am J Dermatopathol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0009-9260(98)80319-X","article-title":"Diffuse neurofibroma of the ankle","volume":"53","author":"Beggs I","year":"1998","journal-title":"Clin Radiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1017\/S0022215100133122","article-title":"Subcutaneous diffuse neurofibroma of the neck: a case report","volume":"110","author":"de Varebeke SJ","year":"1996","journal-title":"J Laryngol Otol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/00006534-200002000-00058","article-title":"Extracranial diffuse neurofibroma with intracranial extension","volume":"105","author":"Erg\u00fcn SS","year":"2000","journal-title":"Plast Reconstr Surg"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"582","DOI":"10.2214\/AJR.07.2589","article-title":"Imaging Appearance of Diffuse Neurofibroma","volume":"190","author":"Hassell DS","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4103\/0974-7753.66919","article-title":"Diffuse neurofibroma of the scalp presenting as circumscribed alopecic patch","volume":"2","author":"Kumar BS","year":"2012","journal-title":"Int J Trichology"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.2214\/ajr.184.5.01841711","article-title":"On the AJR view-box. Diffuse neurofibroma of the arm: MR characteristics.","volume":"184","author":"Huang GS","year":"2005","journal-title":"AJR Am J Roentgenol"}],"container-title":["Anais Brasileiros de Dermatologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abd\/v88n6s1\/0365-0596-abd-88-06-s1-0166.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T15:00:41Z","timestamp":1747666841000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0365-05962013000800166&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":10,"journal-issue":{"issue":"6 suppl 1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0365-05962013000800166"],"URL":"https:\/\/doi.org\/10.1590\/abd1806-4841.20132170","relation":{},"ISSN":["0365-0596"],"issn-type":[{"value":"0365-0596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}