{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:37:25Z","timestamp":1760549845950},"reference-count":39,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eng. Sanit. Ambient."],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>Processos de tratamentos t\u00eam sido alvo de estudos com a finalidade de promover a remo\u00e7\u00e3o dos f\u00e1rmacos na urina humana de forma a garantir a seguran\u00e7a ambiental da utiliza\u00e7\u00e3o dessa como fertilizante na agricultura. Neste artigo foi desenvolvido e validado um m\u00e9todo de CLAE-DF para a determina\u00e7\u00e3o simult\u00e2nea de ofloxacina, norfloxacina e ciprofloxacina na urina humana. O m\u00e9todo proposto descreve uma alternativa eficaz para a determina\u00e7\u00e3o de res\u00edduos de fluoroquinolonas, eliminando o passo de limpeza. Al\u00e9m disso, o m\u00e9todo proposto demonstrou ser seletivo, com boa linearidade (r&gt;0,99), sensibilidade, precis\u00e3o (80% a 107%) e repetitividade. Este m\u00e9todo mostra ser adequado para an\u00e1lises de rotina (de baixo custo, simples, e utilizando pequeno volume de solventes) para abordagens ecol\u00f3gicas.<\/jats:p>","DOI":"10.1590\/s1413-41522015020000114433","type":"journal-article","created":{"date-parts":[[2015,9,12]],"date-time":"2015-09-12T21:43:26Z","timestamp":1442094206000},"page":"307-314","source":"Crossref","is-referenced-by-count":4,"title":["Desenvolvimento e valida\u00e7\u00e3o de m\u00e9todo para quantifica\u00e7\u00e3o simult\u00e2nea de ofloxacina, norfloxacina e ciprofloxacina em urina humana"],"prefix":"10.1590","volume":"20","author":[{"given":"Priscilla Garozi","family":"Zanchetta","sequence":"first","affiliation":[{"name":"Universidade Federal do Esp\u00edrito Santo,  Brazil"}]},{"given":"Angelina","family":"Pena","sequence":"additional","affiliation":[{"name":"Universidade de Coimbra,  Portugal"}]},{"given":"Ricardo Franci","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"UFES,  Brazil"}]}],"member":"530","reference":[{"issue":"9","key":"ref1","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1590\/S0100-40422010000900025","article-title":"Valida\u00e7\u00e3o e estimativa da incerteza de m\u00e9todo para an\u00e1lise de licopeno e \u03b2-caroteno em polpa de tomate por cromatogra\ufb01a l\u00edquida de alta e\ufb01ci\u00eancia","volume":"33","author":"ALVES A.B.","year":"2010","journal-title":"Qu\u00edmica Nova"},{"key":"ref2","article-title":"Resolu\u00e7\u00e3o n\u00ba 899, de 29 de maio de 2003. 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