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Outcomes included percentage of patients continuing therapy for 6 months, medication possession ratios, and time to discontinuation of therapy. The proportion of patients continuing therapy for 6 months was statistically superior for tolterodine (32%) compared with IR oxybutynin (22%, p&lt;0.001). Medication possession ratios were also superior for patients in the tolterodine group (medians 0.83 and 0.64, ranges 0.11\u20131.15 and 0.07\u20131.13, respectively, p&lt;0.001). Oxybutynin was discontinued significantly earlier (mean 45 days) than tolterodine (mean 59 days, p&lt;0.001) and was switched to another therapy more commonly than tolterodine (19% and 14%, respectively). Tolterodine was favored over oxybutynin for several measurements of patient adherence. However, less than one\u2010third of patients continued therapy with either agent for 6 months. The clinical relevance of these differences is unknown.<\/jats:p>","DOI":"10.1592\/phco.20.5.470.35064","type":"journal-article","created":{"date-parts":[[2004,6,18]],"date-time":"2004-06-18T09:41:16Z","timestamp":1087551676000},"page":"470-475","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Immediate\u2010Release Oxybutynin versus Tolterodine in Detrusor Overactivity: A Population Analysis"],"prefix":"10.1002","volume":"20","author":[{"given":"Margareta","family":"Lawrence","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R. 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