{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T07:06:12Z","timestamp":1778310372874,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T00:00:00Z","timestamp":1326672000000},"content-version":"vor","delay-in-days":3302,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacotherapy"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:p>A 52\u2010year\u2010old woman with stage IIIC ovarian cancer and stage IA uterine cancer experienced recurring alopecia areata of her eyebrows, eyelashes, arms, legs, and pubic area beginning 5 months after completing chemotherapy with paclitaxel and carboplatin. The condition recurred in a cyclic fashion over the ensuing months. Alopecia is a well\u2010recognized adverse event associated with chemotherapy; however, to our knowledge, this cyclic pattern of alopecia has not been reported in a patient with cancer. Our report of a cancer survivor who experienced cyclic alopecia areata indicates that this condition may be related to autoimmune changes instigated by chemotherapy. Oncology health care practitioners should evaluate unusual clinical cases of alopecia for underlying pathology.<\/jats:p>","DOI":"10.1592\/phco.23.1.104.31918","type":"journal-article","created":{"date-parts":[[2004,5,10]],"date-time":"2004-05-10T08:05:57Z","timestamp":1084176357000},"page":"104-108","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Recurring Chemotherapy\u2010Associated Alopecia Areata: Case Report and Literature Review"],"prefix":"10.1002","volume":"23","author":[{"given":"Susannah E.","family":"Motl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Fausel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,16]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"739","volume-title":"Clinical dermatology: a color guide to diagnosis and therapy","author":"Habif T.A.","year":"1996"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1982.tb03143.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(00)00124-3"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1973.tb06668.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1967.03130080077025"},{"key":"e_1_2_1_7_2","volume-title":"Taxol (paclitaxel) package insert","author":"Bristol\u2010Myers Squibb Company.","year":"1999"},{"key":"e_1_2_1_8_2","first-page":"107","volume-title":"Cancer chemotherapy handbook","author":"Dorr R.T.","year":"1980"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1970.03170340057013"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1994.tb00693.x"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1983.tb02181.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199410040-00005"},{"key":"e_1_2_1_13_2","volume-title":"Paraplatin (carboplatin) package insert","author":"Bristol\u2010Myers Squibb Company.","year":"1999"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.1995.36.1.97"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1987.01660250050016"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jidsp.5640212"},{"issue":"6","key":"e_1_2_1_17_2","first-page":"541","article-title":"Is alopecia areata an autoimmune\u2010response against melanogenesis\u2010related proteins, exposed by an abnormal MHC class I expression in the anagen hair bulb?","volume":"66","author":"Paus R.","year":"1994","journal-title":"Yale J Biol Med"},{"issue":"5","key":"e_1_2_1_18_2","first-page":"405","article-title":"Treatment of alopecia areata in C3H\/HeJ mice with the topical immuno\u2010suppressant FK506 (tacrolimus)","volume":"11","author":"Freyschmidt\u2010Paul P.","year":"2001","journal-title":"Eur J Dermatol"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1999.tb02049.x"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202x.2001.01583.x"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64659-7"},{"key":"e_1_2_1_22_2","first-page":"5002","article-title":"p53 is essential for chemotherapy\u2010induced hair loss","volume":"60","author":"Botchkarev V.A.","year":"2000","journal-title":"Cancer Res"}],"container-title":["Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1592%2Fphco.23.1.104.31918","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1592\/phco.23.1.104.31918","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T16:21:37Z","timestamp":1761063697000},"score":1,"resource":{"primary":{"URL":"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/10.1592\/phco.23.1.104.31918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["10.1592\/phco.23.1.104.31918"],"URL":"https:\/\/doi.org\/10.1592\/phco.23.1.104.31918","archive":["Portico"],"relation":{},"ISSN":["0277-0008","1875-9114"],"issn-type":[{"value":"0277-0008","type":"print"},{"value":"1875-9114","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1]]},"assertion":[{"value":"2012-01-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}