{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:52:22Z","timestamp":1761511942538,"version":"build-2065373602"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T00:00:00Z","timestamp":1326672000000},"content-version":"vor","delay-in-days":3302,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacotherapy"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:p><jats:bold>Study Objective.<\/jats:bold> To evaluate and improve adherence to American Diabetes Association guidelines for prophylactic aspirin therapy in ambulatory patients with diabetes using a pharmacy\u2010directed intervention.<\/jats:p><jats:p><jats:bold>Design.<\/jats:bold> Unblinded, single intervention.<\/jats:p><jats:p><jats:bold>Setting.<\/jats:bold> Rural, primary care clinic.<\/jats:p><jats:p><jats:bold>Subjects.<\/jats:bold> Eighty\u2010five patients with a diagnosis of diabetes mellitus.<\/jats:p><jats:p><jats:bold>Intervention.<\/jats:bold> Patients with diabetes were identified from database searches and routine clinic visits. Medical records were screened for aspirin use, allergies, adverse events, and contraindications. During routine clinic visits or structured telephone interviews, patients with indications for aspirin therapy were advised to begin enteric\u2010coated aspirin 81 mg\/day. A follow\u2010up survey assessed adherence.<\/jats:p><jats:p><jats:bold>Measurements and Main Results.<\/jats:bold> At baseline, 28 (33%) of 85 patients were receiving aspirin therapy. An additional 8 patients had contraindications to aspirin, and 2 patients had no indications for aspirin therapy. Aspirin was recommended to 27 patients during clinic interventions and to 15 patients during telephone interventions. Two patients declined the recommendation. At the completion of this intervention, 70 (82%) of 85 patients were receiving daily aspirin or had accepted the recommendation to begin therapy.<\/jats:p><jats:p><jats:bold>Conclusions.<\/jats:bold> A pharmacy\u2010directed intervention increased prophylactic aspirin therapy in patients with diabetes from 33% of patients at baseline to 82% at the end of the study. The intervention, which has a simple, patient\u2010focused design, serves as a template for improving aspirin prophylaxis among patients with diabetes in other ambulatory settings.<\/jats:p>","DOI":"10.1592\/phco.23.1.73.31923","type":"journal-article","created":{"date-parts":[[2004,5,10]],"date-time":"2004-05-10T08:05:57Z","timestamp":1084176357000},"page":"73-79","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Improving Aspirin Prophylaxis in a Primary Care Diabetic Population"],"prefix":"10.1002","volume":"23","author":[{"given":"John J.","family":"Faragon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy M.","family":"Waite","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric H.","family":"Hobson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Seoldo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenny A.","family":"VanAmburgh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hedy","family":"Migden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,16]]},"reference":[{"volume-title":"Diabetes in America","year":"1995","author":"National Institutes of Health.","key":"e_1_2_1_2_2"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.16.2.434"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.16.1873"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198907203210301"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1001\/jama.1992.03490100090033","article-title":"Aspirin effects on mortality and morbidity in patients with diabetes mellitus","volume":"268","author":"Early Treatment Diabetic Retinopathy Study Investigators.","year":"1992","journal-title":"JAMA"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)04311-6"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1136\/bmj.308.6921.81","article-title":"Collaborative overview of randomized trials of antiplatelet therapy: prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients","volume":"308","author":"Antiplatelet Trialists' Collaboration.","year":"1994","journal-title":"BMJ"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.20.11.1767"},{"issue":"1","key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"78","DOI":"10.2337\/diacare.25.2007.S78","article-title":"Clinical practice recommendations. 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