{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:46:07Z","timestamp":1761093967016,"version":"build-2065373602"},"reference-count":4,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T00:00:00Z","timestamp":1326672000000},"content-version":"vor","delay-in-days":2877,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacotherapy"],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:p><jats:bold>Study Objective.<\/jats:bold> To determine whether appropriate thyroid function measurements were being conducted in patients receiving care at a multidisciplinary heart failure clinic.<\/jats:p><jats:p><jats:bold>Design.<\/jats:bold> Retrospective chart review.<\/jats:p><jats:p><jats:bold>Setting.<\/jats:bold> University\u2010affiliated outpatient clinic.<\/jats:p><jats:p><jats:bold>Patients.<\/jats:bold> One hundred ninety\u2010three patients with heart failure.<\/jats:p><jats:p><jats:bold>Intervention.<\/jats:bold> Patients enrolled in the heart failure clinic at the Medical University of South Carolina from January 2000\u2010April 2003 were identified. Their medical records were reviewed for demographics, New York Heart Association (NYHA) functional classification, laboratory data, and date of most recent heart failure clinic appointment.<\/jats:p><jats:p><jats:bold>Measurements and Main Results.<\/jats:bold> The records of 193 patients (43% women) were reviewed. Overall and subgroup analyses were performed based on patient characteristics such as presence of thyroid\u2010stimulating hormone (TSH) level, interval since last heart failure clinic appointment, presence of thyroid replacement therapy, amiodarone use, NYHA functional class, and attending physician. Of the 193 patients, 77 (40%) had appropriate TSH monitoring, whereas 10 (32%) of 31 patients receiving amiodarone had appropriate monitoring. Forty\u2010four (27%) patients not receiving amiodarone had no record of a TSH level. In 22 patients (11%), hypothyroidism was diagnosed and treated, whereas 16 patients (8%) had an abnormal TSH level but received no therapy.<\/jats:p><jats:p><jats:bold>Conclusion.<\/jats:bold> Forty percent of the 193 patients at this outpatient heart failure clinic received appropriate TSH monitoring. An opportunity exists for protocol implementation and education of pharmacists, nurse practitioners, and physicians concerning appropriate thyroid function monitoring in the heart failure population.<\/jats:p>","DOI":"10.1592\/phco.24.4.358.33171","type":"journal-article","created":{"date-parts":[[2004,5,21]],"date-time":"2004-05-21T08:33:58Z","timestamp":1085128438000},"page":"358-361","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of Hypothyroidism in Patients with Chronic Heart Failure"],"prefix":"10.1002","volume":"24","author":[{"given":"Sarah C.","family":"Middleton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne P.","family":"Spencer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,16]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200102153440707"},{"key":"e_1_2_1_3_2","unstructured":"HuntSA BakerDW ChinMH et al.ACC\/AHA guidelines for the evaluation and management of chronic heart failure in the adult: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure) 2001. Available fromhttp:www.acc.orgclinicalguidelinesfailurehf_index.htm. Accessed February 2003."},{"key":"e_1_2_1_4_2","first-page":"458","article-title":"AACE medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism","volume":"8","author":"American Association of Clinical Endocrinologists (AACE) Thyroid Task Force.","year":"2002","journal-title":"Endocr Pract"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.12.1741"}],"container-title":["Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1592%2Fphco.24.4.358.33171","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1592\/phco.24.4.358.33171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:29:05Z","timestamp":1761053345000},"score":1,"resource":{"primary":{"URL":"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/10.1592\/phco.24.4.358.33171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":4,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["10.1592\/phco.24.4.358.33171"],"URL":"https:\/\/doi.org\/10.1592\/phco.24.4.358.33171","archive":["Portico"],"relation":{},"ISSN":["0277-0008","1875-9114"],"issn-type":[{"type":"print","value":"0277-0008"},{"type":"electronic","value":"1875-9114"}],"subject":[],"published":{"date-parts":[[2004,3]]},"assertion":[{"value":"2012-01-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}