{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:39:26Z","timestamp":1770511166312,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,1,6]],"date-time":"2012-01-06T00:00:00Z","timestamp":1325808000000},"content-version":"vor","delay-in-days":219,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacotherapy"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:p><jats:bold>Study Objective.<\/jats:bold> To determine the rate of invasive fungal infection among the lung transplant population at a center that does not provide routine systemic antifungal prophylaxis, and to compare that rate with rates currently reported in the literature.<\/jats:p><jats:p><jats:bold>Design.<\/jats:bold> Retrospective medical record review.<\/jats:p><jats:p><jats:bold>Setting.<\/jats:bold> University\u2010affiliated lung transplant center.<\/jats:p><jats:p><jats:bold>Patients.<\/jats:bold> Two hundred forty\u2010two adults without cystic fibrosis who underwent lung transplantation between March 1, 1994, and June 30, 2006.<\/jats:p><jats:p><jats:bold>Measurements and Main Results.<\/jats:bold> Patients were followed by the adult lung transplant service. Twenty\u2010three cases of invasive fungal infections were identified in 22 patients, resulting in a 9.1% overall invasive fungal infection rate in our study population. <jats:italic>Aspergillus<\/jats:italic> infections were the most common type of fungal infection identified, occurring in 11 (47.8%) of the 23 cases, with an overall rate of 4.5% (11\/242 patients). Invasive fungal infections in lung transplant recipients have been reported in the literature at a rate 15\u201335%, with rates of <jats:italic>Aspergillus<\/jats:italic> infections reported as 3\u201315%.<\/jats:p><jats:p><jats:bold>Conclusion.<\/jats:bold> Despite the absence of routine systemic antifungal prophylaxis, the overall invasive fungal infection rate and the <jats:italic>Aspergillus<\/jats:italic> infection rate in these lung transplant recipients do not appear to be higher than the rates reported in the literature.<\/jats:p>","DOI":"10.1592\/phco.31.6.537","type":"journal-article","created":{"date-parts":[[2011,5,27]],"date-time":"2011-05-27T10:50:49Z","timestamp":1306493449000},"page":"537-545","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Invasive Fungal Infections in Lung Transplant Recipients Not Receiving Routine Systemic Antifungal Prophylaxis: 12\u2010Year Experience at a University Lung Transplant Center"],"prefix":"10.1002","volume":"31","author":[{"given":"Marlena F.","family":"Pinney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy F.","family":"Rosenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Hampp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise","family":"Schain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olufemi","family":"Akindipe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maher","family":"Baz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,6]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2005.01128.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.1.44-69.2005"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.119.1.169"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(02)00477-1"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3062.2001.003003161.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/430602"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00390.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3062.2002.t01-2-02002.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.115.5.1301"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2005.05.003"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.13a33.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01548.x"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02734.x"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2003.09.028"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_2_1_17_2","unstructured":"Janssen Pharmaceutica.Sporonox (itraconazole) package insert. Toronto Ontario Canada;2001."},{"key":"e_1_2_1_18_2","unstructured":"U.S. Food and Drug Administration Center for Drug Evaluation and Research.Public health advisory May 9 2001. Available fromhttp:www.fda.govcderdrugadvisorySporanox\u2010lamisiladvisory.htm. AccessedNovember 14 2007."},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12281-009-0004-z"}],"container-title":["Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1592%2Fphco.31.6.537","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1592\/phco.31.6.537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T16:06:06Z","timestamp":1761062766000},"score":1,"resource":{"primary":{"URL":"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/10.1592\/phco.31.6.537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.1592\/phco.31.6.537"],"URL":"https:\/\/doi.org\/10.1592\/phco.31.6.537","archive":["Portico"],"relation":{},"ISSN":["0277-0008","1875-9114"],"issn-type":[{"value":"0277-0008","type":"print"},{"value":"1875-9114","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6]]},"assertion":[{"value":"2012-01-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}