{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T13:07:20Z","timestamp":1778764040070,"version":"3.51.4"},"reference-count":16,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T00:00:00Z","timestamp":1399248000000},"content-version":"vor","delay-in-days":124,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neoplasia"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1593\/neo.131900","type":"journal-article","created":{"date-parts":[[2015,5,20]],"date-time":"2015-05-20T14:50:36Z","timestamp":1432133436000},"page":"97-W29","source":"Crossref","is-referenced-by-count":54,"title":["Personalized Ovarian Cancer Disease Surveillance and Detection of Candidate Therapeutic Drug Target in Circulating Tumor DNA"],"prefix":"10.1016","volume":"16","author":[{"given":"John A.","family":"Martignetti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Camacho-Vanegas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nolan","family":"Priedigkeit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalina","family":"Camacho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leopold","family":"Garnar-Wortzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dagny","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bojan","family":"Losic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hardik","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pratik","family":"Lahiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Chee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Schadt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Dottino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1593\/neo.131900_bib1","doi-asserted-by":"crossref","first-page":"207ps14","DOI":"10.1126\/scitranslmed.3006305","article-title":"Going with the flow: from circulating tumor cells to DNA","volume":"5","author":"Bidard","year":"2013","journal-title":"Sci Transl Med"},{"key":"10.1593\/neo.131900_bib2","first-page":"241","article-title":"Les acides nucl\u00e9iques du plasma sanguin chez l'homme","volume":"142","author":"Mandel","year":"1948","journal-title":"C R Acad Sci Paris"},{"key":"10.1593\/neo.131900_bib3","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1172\/JCI107165","article-title":"The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythematosus and other diseases","volume":"52","author":"Koffler","year":"1973","journal-title":"J Clin Invest"},{"key":"10.1593\/neo.131900_bib4","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/nm.1789","article-title":"Circulating mutant DNA to assess tumor dynamics","volume":"14","author":"Diehl","year":"2008","journal-title":"Nat Med"},{"key":"10.1593\/neo.131900_bib5","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1056\/NEJMoa1213261","article-title":"Analysis of circulating tumor DNA to monitor metastatic breast cancer","volume":"368","author":"Dawson","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1593\/neo.131900_bib6","doi-asserted-by":"crossref","first-page":"136ra68","DOI":"10.1126\/scitranslmed.3003726","article-title":"Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA","volume":"4","author":"Forshew","year":"2012","journal-title":"Sci Transl Med"},{"key":"10.1593\/neo.131900_bib7","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nature12065","article-title":"Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA","volume":"497","author":"Murtaza","year":"2013","journal-title":"Nature"},{"key":"10.1593\/neo.131900_bib8","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1002\/gcc.20815","article-title":"Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors","volume":"49","author":"McBride","year":"2010","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1593\/neo.131900_bib9","doi-asserted-by":"crossref","first-page":"20ra14","DOI":"10.1126\/scitranslmed.3000702","article-title":"Development of personalized tumor biomarkers using massively parallel sequencing","volume":"2","author":"Leary","year":"2010","journal-title":"Sci Transl Med"},{"key":"10.1593\/neo.131900_bib10","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1093\/bioinformatics\/btr265","article-title":"FusionHunter: identifying fusion transcripts in cancer using paired-end RNA-seq","volume":"27","author":"Li","year":"2011","journal-title":"Bioinformatics"},{"issue":"8","key":"10.1593\/neo.131900_bib11","doi-asserted-by":"crossref","first-page":"R72","DOI":"10.1186\/gb-2011-12-8-r72","article-title":"TopHat-Fusion: an algorithm for discovery of novel fusion transcripts","volume":"12","author":"Kim","year":"2011","journal-title":"Genome Biol"},{"key":"10.1593\/neo.131900_bib12","doi-asserted-by":"crossref","first-page":"e1001138","DOI":"10.1371\/journal.pcbi.1001138","article-title":"deFuse: an algorithm for gene fusion discovery in tumor RNA-Seq data","volume":"7","author":"McPherson","year":"2011","journal-title":"PLoS Comput Biol"},{"key":"10.1593\/neo.131900_bib13","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1158\/2159-8290.CD-13-0050","article-title":"Identification of targetable FGFR gene fusions in diverse cancers","volume":"3","author":"Wu","year":"2013","journal-title":"Cancer Discov"},{"key":"10.1593\/neo.131900_bib14","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1196\/annals.1368.031","article-title":"Quantification of total plasma cell-free DNA in ovarian cancer using realtime PCR","volume":"1075","author":"Kamat","year":"2006","journal-title":"Ann NY Acad Sci"},{"key":"10.1593\/neo.131900_bib15","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/nature10166","article-title":"Integrated genomic analyses of ovarian carcinoma","volume":"474","year":"2011","journal-title":"Nature"},{"key":"10.1593\/neo.131900_bib16","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.1002\/cncr.25203","article-title":"Commentary: CA 125 and the detection of recurrent ovarian cancer: a reasonably accurate biomarker for a difficult disease","volume":"116","author":"Bast","year":"2010","journal-title":"Cancer"}],"container-title":["Neoplasia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1476558614800092?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1476558614800092?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T09:25:53Z","timestamp":1537608353000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1476558614800092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S1476558614800092"],"URL":"https:\/\/doi.org\/10.1593\/neo.131900","relation":{},"ISSN":["1476-5586"],"issn-type":[{"value":"1476-5586","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}