{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:26:59Z","timestamp":1777523219433,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2006,11,1]],"date-time":"2006-11-01T00:00:00Z","timestamp":1162339200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:p>We report on a child with midline facial defects with hypertelorism (MFDH), median cleft lip, sphenoidal ventriculocele, partial agenesis of the corpus callosum, and low-grade astrocytoma in the cervicomedullary junction. This combination of findings has not been reported previously. Although this association might be casual, it demonstrates a relationship between disorders of frontonasal process and posterior fossae. It also suggests that individuals with MFDH might require a prospective follow-up with central nervous system magnetic resonance imaging.<\/jats:p>","DOI":"10.1597\/05-099","type":"journal-article","created":{"date-parts":[[2005,12,29]],"date-time":"2005-12-29T02:25:02Z","timestamp":1135823102000},"page":"748-751","source":"Crossref","is-referenced-by-count":3,"title":["Midline Facial Defects with Hypertelorism and Low-Grade Astrocytoma: A Previously Undescribed Association"],"prefix":"10.1177","volume":"43","author":[{"given":"Silvyo David Ara\u00fajo","family":"Giffoni","sequence":"first","affiliation":[{"name":"Departamento de Gen\u00e9tica M\u00e9dica, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Cendes","sequence":"additional","affiliation":[{"name":"Departamento de Neurologia, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade 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